Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable calcium-binding mitochondrial carrier F17E5.2

Gene

F17E5.2

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Calcium-dependent mitochondrial solute carrier.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Calcium bindingi83 – 94121PROSITE-ProRule annotationAdd
BLAST
Calcium bindingi149 – 160122PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Calcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable calcium-binding mitochondrial carrier F17E5.2
Gene namesi
ORF Names:F17E5.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiF17E5.2; CE37355; WBGene00008924.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei248 – 26518Helical; Name=1Sequence analysisAdd
BLAST
Transmembranei303 – 32220Helical; Name=2Sequence analysisAdd
BLAST
Transmembranei348 – 36114Helical; Name=3Sequence analysisAdd
BLAST
Transmembranei399 – 41820Helical; Name=4Sequence analysisAdd
BLAST
Transmembranei441 – 45818Helical; Name=5Sequence analysisAdd
BLAST
Transmembranei500 – 51718Helical; Name=6Sequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 531531Probable calcium-binding mitochondrial carrier F17E5.2PRO_0000090605Add
BLAST

Proteomic databases

EPDiQ19529.
PaxDbiQ19529.
PRIDEiQ19529.

Interactioni

Protein-protein interaction databases

STRINGi6239.F17E5.2.

Structurei

3D structure databases

ProteinModelPortaliQ19529.
SMRiQ19529. Positions 78-226, 246-507.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini70 – 10536EF-hand 1PROSITE-ProRule annotationAdd
BLAST
Domaini106 – 13530EF-hand 2PROSITE-ProRule annotationAdd
BLAST
Domaini136 – 17136EF-hand 3PROSITE-ProRule annotationAdd
BLAST
Domaini172 – 20736EF-hand 4PROSITE-ProRule annotationAdd
BLAST
Repeati242 – 32887Solcar 1Add
BLAST
Repeati338 – 42487Solcar 2Add
BLAST
Repeati435 – 52591Solcar 3Add
BLAST

Sequence similaritiesi

Contains 4 EF-hand domains.PROSITE-ProRule annotation
Contains 3 Solcar repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0036. Eukaryota.
ENOG410XQ4P. LUCA.
GeneTreeiENSGT00760000119245.
HOGENOMiHOG000165728.
InParanoidiQ19529.
KOiK14684.
OMAiLQCSNLD.
OrthoDBiEOG7V7661.
PhylomeDBiQ19529.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
1.50.40.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF13499. EF-hand_7. 1 hit.
PF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00926. MITOCARRIER.
SMARTiSM00054. EFh. 3 hits.
[Graphical view]
SUPFAMiSSF103506. SSF103506. 1 hit.
SSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 3 hits.
PS50920. SOLCAR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q19529-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVTAESPSL RGGSILENKQ ELIDLKNIGE HARTVQPFKT SKHQPLIQGS
60 70 80 90 100
VSKEAAIATH SALHFDLTPE KEKKIRDMYD RLDADNDGSI DIRDLTQALS
110 120 130 140 150
LQAHIPASVA PKLLERMKSE HSDRVTYADF TNYVIAHEAR LAEVFDKIDL
160 170 180 190 200
NSDGEVDMAE IKSYCKEMGV NLDDQKAMSI VKKMDQSGSS SVNLNEFQDF
210 220 230 240 250
MLLYPSTDMR DMVDFWRHNL IIDIGEDGQV PEDFTPQELL SGVWWRHLVA
260 270 280 290 300
GGVAGAMSRT CTAPFDRIKV YLQVNSTKTN KLGVVSCVHL LHAEGGIKSF
310 320 330 340 350
WRGNGINVIK IAPESAMKFM CYDQIKRWMQ EYKGGAELST IERLLAGSSA
360 370 380 390 400
GAISQTAIYP MEVMKTRLAL RRTGQLDKGM FHFAHKMYTK EGIKCFYKGY
410 420 430 440 450
LPNLLGIIPY AGIDLTVYES LKSMYTKYYT EHTEPGVLAL LACGTCSSTC
460 470 480 490 500
GQLASYPLAL VRTRLQARAI SPKNSTQPDT MVGQFKHILQ TEGFTGLYRG
510 520 530
ITPNFMKVIP AVSISYVVYE KVRKQLGATM T
Length:531
Mass (Da):59,275
Last modified:May 24, 2005 - v4
Checksum:iFE1CC396D6BCB345
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z50873 Genomic DNA. Translation: CAA90761.4.
PIRiG89667.
T21074.
RefSeqiNP_510081.3. NM_077680.5.
UniGeneiCel.19859.

Genome annotation databases

EnsemblMetazoaiF17E5.2; F17E5.2; WBGene00008924.
GeneIDi181399.
KEGGicel:CELE_F17E5.2.
UCSCiF17E5.2. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z50873 Genomic DNA. Translation: CAA90761.4.
PIRiG89667.
T21074.
RefSeqiNP_510081.3. NM_077680.5.
UniGeneiCel.19859.

3D structure databases

ProteinModelPortaliQ19529.
SMRiQ19529. Positions 78-226, 246-507.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F17E5.2.

Proteomic databases

EPDiQ19529.
PaxDbiQ19529.
PRIDEiQ19529.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF17E5.2; F17E5.2; WBGene00008924.
GeneIDi181399.
KEGGicel:CELE_F17E5.2.
UCSCiF17E5.2. c. elegans.

Organism-specific databases

CTDi181399.
WormBaseiF17E5.2; CE37355; WBGene00008924.

Phylogenomic databases

eggNOGiKOG0036. Eukaryota.
ENOG410XQ4P. LUCA.
GeneTreeiENSGT00760000119245.
HOGENOMiHOG000165728.
InParanoidiQ19529.
KOiK14684.
OMAiLQCSNLD.
OrthoDBiEOG7V7661.
PhylomeDBiQ19529.

Miscellaneous databases

PROiQ19529.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
1.50.40.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF13499. EF-hand_7. 1 hit.
PF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00926. MITOCARRIER.
SMARTiSM00054. EFh. 3 hits.
[Graphical view]
SUPFAMiSSF103506. SSF103506. 1 hit.
SSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 3 hits.
PS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiCMC3_CAEEL
AccessioniPrimary (citable) accession number: Q19529
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: May 24, 2005
Last modified: July 6, 2016
This is version 124 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.