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Protein

Probable calcium-binding mitochondrial carrier F17E5.2

Gene

F17E5.2

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Calcium-dependent mitochondrial solute carrier.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi83 – 941PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi149 – 1602PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport
LigandCalcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable calcium-binding mitochondrial carrier F17E5.2
Gene namesi
ORF Names:F17E5.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiF17E5.2 ; CE37355 ; WBGene00008924

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei248 – 265Helical; Name=1Sequence analysisAdd BLAST18
Transmembranei303 – 322Helical; Name=2Sequence analysisAdd BLAST20
Transmembranei348 – 361Helical; Name=3Sequence analysisAdd BLAST14
Transmembranei399 – 418Helical; Name=4Sequence analysisAdd BLAST20
Transmembranei441 – 458Helical; Name=5Sequence analysisAdd BLAST18
Transmembranei500 – 517Helical; Name=6Sequence analysisAdd BLAST18

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000906051 – 531Probable calcium-binding mitochondrial carrier F17E5.2Add BLAST531

Proteomic databases

EPDiQ19529
PaxDbiQ19529
PeptideAtlasiQ19529
PRIDEiQ19529

Expressioni

Gene expression databases

BgeeiWBGene00008924

Interactioni

Protein-protein interaction databases

STRINGi6239.F17E5.2

Structurei

3D structure databases

ProteinModelPortaliQ19529
SMRiQ19529
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini70 – 105EF-hand 1PROSITE-ProRule annotationAdd BLAST36
Domaini106 – 135EF-hand 2PROSITE-ProRule annotationAdd BLAST30
Domaini136 – 171EF-hand 3PROSITE-ProRule annotationAdd BLAST36
Domaini172 – 207EF-hand 4PROSITE-ProRule annotationAdd BLAST36
Repeati242 – 328Solcar 1Add BLAST87
Repeati338 – 424Solcar 2Add BLAST87
Repeati435 – 525Solcar 3Add BLAST91

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0036 Eukaryota
ENOG410XQ4P LUCA
GeneTreeiENSGT00880000137904
HOGENOMiHOG000165728
InParanoidiQ19529
KOiK14684
OMAiMQVQTNR
OrthoDBiEOG091G0C8S
PhylomeDBiQ19529

Family and domain databases

CDDicd00051 EFh, 1 hit
Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR002067 Mit_carrier
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF13499 EF-hand_7, 1 hit
PF00153 Mito_carr, 3 hits
PRINTSiPR00926 MITOCARRIER
SMARTiView protein in SMART
SM00054 EFh, 3 hits
SUPFAMiSSF103506 SSF103506, 1 hit
SSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 2 hits
PS50222 EF_HAND_2, 3 hits
PS50920 SOLCAR, 3 hits

Sequencei

Sequence statusi: Complete.

Q19529-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVTAESPSL RGGSILENKQ ELIDLKNIGE HARTVQPFKT SKHQPLIQGS
60 70 80 90 100
VSKEAAIATH SALHFDLTPE KEKKIRDMYD RLDADNDGSI DIRDLTQALS
110 120 130 140 150
LQAHIPASVA PKLLERMKSE HSDRVTYADF TNYVIAHEAR LAEVFDKIDL
160 170 180 190 200
NSDGEVDMAE IKSYCKEMGV NLDDQKAMSI VKKMDQSGSS SVNLNEFQDF
210 220 230 240 250
MLLYPSTDMR DMVDFWRHNL IIDIGEDGQV PEDFTPQELL SGVWWRHLVA
260 270 280 290 300
GGVAGAMSRT CTAPFDRIKV YLQVNSTKTN KLGVVSCVHL LHAEGGIKSF
310 320 330 340 350
WRGNGINVIK IAPESAMKFM CYDQIKRWMQ EYKGGAELST IERLLAGSSA
360 370 380 390 400
GAISQTAIYP MEVMKTRLAL RRTGQLDKGM FHFAHKMYTK EGIKCFYKGY
410 420 430 440 450
LPNLLGIIPY AGIDLTVYES LKSMYTKYYT EHTEPGVLAL LACGTCSSTC
460 470 480 490 500
GQLASYPLAL VRTRLQARAI SPKNSTQPDT MVGQFKHILQ TEGFTGLYRG
510 520 530
ITPNFMKVIP AVSISYVVYE KVRKQLGATM T
Length:531
Mass (Da):59,275
Last modified:May 24, 2005 - v4
Checksum:iFE1CC396D6BCB345
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z50873 Genomic DNA Translation: CAA90761.4
PIRiG89667
T21074
RefSeqiNP_510081.3, NM_077680.5
UniGeneiCel.19859

Genome annotation databases

EnsemblMetazoaiF17E5.2; F17E5.2; WBGene00008924
GeneIDi181399
KEGGicel:CELE_F17E5.2
UCSCiF17E5.2 c. elegans

Similar proteinsi

Entry informationi

Entry nameiCMC3_CAEEL
AccessioniPrimary (citable) accession number: Q19529
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: May 24, 2005
Last modified: March 28, 2018
This is version 135 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

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