Unreviewed, UniProtKB/TrEMBL Q19482 (Q19482_CAEEL)

Names and origin

Protein names

Submitted name:
    Protein F15B9.7, confirmed by transcript evidence EMBL CAB01449.3
Submitted name:
    Flamingo-like protein FMI-1 EMBL AAQ84880.1

Gene names

Name:	cdh-6 WormBase WBGene00000398 WormPep F15B9.7
Synonyms:	fmi-1 EMBL CAB01449.3
ORF Names:	F15B9.7 EMBL CAB01449.3 WormPep F15B9.7

Organism

Caenorhabditis elegans [Complete proteome] EMBL CAB01449.3

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	2596 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 GPS domain.

Ontologies

Keywords
Cellular component	Membrane
Domain	EGF-like domain RuleBase RU003701V0 Spearmint SPM006209 Repeat Spearmint SPM006209 Transmembrane Spearmint SPM002126
Ligand	Calcium RuleBase RU000484V3
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	homophilic cell adhesion Inferred from electronic annotation. Source: InterPro neuropeptide signaling pathway Inferred from electronic annotation. Source: InterPro positive regulation of growth rate Inferred from mutant phenotype. Source: WormBase reproduction Inferred from mutant phenotype. Source: WormBase
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: InterPro
Molecular function	G-protein coupled receptor activity Inferred from electronic annotation. Source: InterPro calcium ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q19482-1 [UniParc]. Last modified April 29, 2008. Version 4. Checksum: 659A425FDD3C73BC	FASTA	2,596	288,351
	10 20 30 40 50 60 MMLDRIMFLL FFILSLVIGS FSEYLDDKYY STNSIDVVCK PCAVPSSNSV IWLPASRPPC 70 80 90 100 110 120 LHPGQPIIHW PDLSDNLACP VPGLPDSVHS SQISLLEGEG LLLTKERICF FDGPIDFHYD 130 140 150 160 170 180 YVCDGKLYRS KMRIGHSIAS KKKLETRRTK RWARRRNPDA NAVHFQQEKY VKELPEDTPI 190 200 210 220 230 240 ETIIASVKAS HASSQPLYYS MVAPQDSRSQ NLFTLDTMSG EIRLAKSMDR EVLDKHILKV 250 260 270 280 290 300 TAYERVDPTI SASTTVVVHV LDVQDNSPIF EKDSYFGEIR EDAPIGTTVL SVFARDLDSG 310 320 330 340 350 360 ENGEIEYSLG EGNGKNLLAI NAKSGVIQTA APLDRETLSL IRLDVIASDK GTPKRESTAM 370 380 390 400 410 420 VEITVVDVND NAPVFASDSY NVTILENITI PAVIATVKAT DEDFGTNGKV HYSMASSSGI 430 440 450 460 470 480 GGLTIDYSTG EVTLRERIDA KNSPITAVIR AKDGAQPALS STVPLTINVI DINDHAPTLI 490 500 510 520 530 540 AAQKMITLEE NVAIGEEVGR VYAIDEDSGP NGIIKYSMEG SEDFIIDEDS GLIKTTKLLD 550 560 570 580 590 600 RETTARYSLK VTARDMGTPS LNTSTTIAVV LKDINDNAPT FDKKEYNVTI SEEMPRGSQI 610 620 630 640 650 660 ITLKAVDNDE DQKITYRIEE ADREVFSILD IGDQGAILSV SGELKRQDHK VRVEISATDQ 670 680 690 700 710 720 GGLQGRCVVN VFIDDVNSAP YFNDHPFSVK IPEHSPIGYP VITLKAEDHD RGDNARIVYS 730 740 750 760 770 780 IDSSQFFRID PSSGDISVSS DLDREDRATF SVIVTASDHA SPPLNTSTQI EVILDDINDN 790 800 810 820 830 840 SPQFTSSSYA ATISEDIPVG TSFLQVSAID ADIGPNGIVD YFLNESSSSP SIQLFRLDRT 850 860 870 880 890 900 SGTLRVSSKL DREQFAVIVL PIFARDRGTP SLSAASEITL TLSDVNDNAP TFEQLSYDLY 910 920 930 940 950 960 IAENSPVGST VGTIVARDAD EGDNADISFR IFGGADAKLF DIEEDAEQNG VVRILTRAEF 970 980 990 1000 1010 1020 DYEAKANKFF FELQASSGQL SSTVPVRIHV SDVNDNKPAL KDFVILMNRF DNVQMARQIG 1030 1040 1050 1060 1070 1080 FIPAFDPDQN ATLEYFLEEN DLIEAEKYTG KILVKQEWKR NMDVSFKTCV SDGANTECST 1090 1100 1110 1120 1130 1140 CRFIHVLVEP EWLSESFTLS LARMTVDDFW DPLVFQRFRD AMSTLSNWKP SDIHVIGVKQ 1150 1160 1170 1180 1190 1200 HLDDVIYINI AITDHGRVVR GWRAIELVKE SIKKLEKMTL LQVEVIRDES CANEPCSHMA 1210 1220 1230 1240 1250 1260 KCRQTQKFVG EMKAHETDNF IARTLNTVNT FVCECPSGFT SSGAHGDCDT RIDECYRGRC 1270 1280 1290 1300 1310 1320 SNNSTCVAFE NTYQCECKPG WIGRHCEISV HALTCVPGYC MSDSLCELDG NQMKCRHCKY 1330 1340 1350 1360 1370 1380 HGEDTDERCR LRSVSFDGEG LLNVNLDLPR TQWTMKFRVS TIAHNGVLVF TGDKRSDFVE 1390 1400 1410 1420 1430 1440 VSVVDRVLKV QFSLGGEKID AKMENDVENR INDGEWHTVA LEYSNKQITM SLDDCETNPS 1450 1460 1470 1480 1490 1500 LLLNTSPNCA IRAKLNLEKK CEDPTVPCYR YLDISNGLFL GGRPGTSKQI EKAFSGCISD 1510 1520 1530 1540 1550 1560 LSVDKEDVDF STIKEMHKVG QVHEGCKHRK DFCSTSDGQC SATSKCVNRW GGRICSCPQS 1570 1580 1590 1600 1610 1620 VHSTGECVGA LGTQDLRGHS LFEEESFVLY QPSQVSVPFE VSFEFRTSRA DMQVFALEFT 1630 1640 1650 1660 1670 1680 QRSVHYNLEV DDGTLKYNIG DSEVELPAPE VTSKHWMNVV IKFEADSVAT SINGIYSAEA 1690 1700 1710 1720 1730 1740 KASISDMNLE SLYFGIAPGT GHPSRFEGCI RNVLVDGRSI SVKKKGKTRA GCVVPNRCSV 1750 1760 1770 1780 1790 1800 DSICPAESTC HRAWNKHKCK CHKSFVGDTC LPVCSVANVC SSGTCVSSNT TAGYECICPA 1810 1820 1830 1840 1850 1860 GKTGKNCQLE APKQMCPSGW WGTFPRCRRC SCAQTKDYEA QCDKKTGACQ CKKSHFSTIN 1870 1880 1890 1900 1910 1920 GCVKCECGFG ADSTECSADG HCKCNGDAVG RRCDRCSRFD HQLDSKTLKC RPVSGKCPSE 1930 1940 1950 1960 1970 1980 IEYSIQWPAS QKGSIVRQSC PVGESGLATR KCLETGRWSD VNAWNCTRPE YSIMVNKFEI 1990 2000 2010 2020 2030 2040 LEPSKLLTMV ANATNTESSI RGRNQQIAAE ALSRLVDYEQ SMPMKGRAHI KDMKFTEKLI 2050 2060 2070 2080 2090 2100 ESLGRVMSEQ PADEYSTLIS KLWNYAETVA EIHENVNFLS PFFVANDHIV FASDKLDFGN 2110 2120 2130 2140 2150 2160 ILPKFNNFVD LRPTGFPRVR AIVTGTTQVV YSIVPYPRCN RCENPMIAIV ANTSDPVIVE 2170 2180 2190 2200 2210 2220 FEIEEDDGWK YPECVRFDEK SGTWTARGAA LIGLNLTHAA CEYNRIGVFT MFVNDQSSSI 2230 2240 2250 2260 2270 2280 VRVAQMDNMT SPAIAGVALF LCFLSILLTL SRRSLKTHSV RIGFILFFAI NILNLFFVHK 2290 2300 2310 2320 2330 2340 TAINQAYCPV RNAMLSFTSS APFAWLFLYG LYIYRMLADG SSSPSLTTSL LVGIVFPCLI 2350 2360 2370 2380 2390 2400 SFTTFFVTDQ CSLSPHLWLF WCIILPIGLF LLLSFYAAAT SVLVSLHKKY DVFVAKYNVK 2410 2420 2430 2440 2450 2460 RAVFQHFILT IFTLGMTLTG LFANQLPLPM EIMEISQSII YLIAALVIFL WCVCDITTKA 2470 2480 2490 2500 2510 2520 SDSNPSMWLD NQKSVMAEST MADPQCASPL LSPRHQHHEV PMDSEWVPDV NPSNHYHTSI 2530 2540 2550 2560 2570 2580 NEPDTPRRLL LPQNRDVINI LSSPDQILNE GVGHVYRNNM GSLPRLRSAQ DEADDAYYTY 2590 TASRKYKNTT STFNRE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.
[2]	"Molecular and Evolutionary Characterization of family B G-protein coupled receptors in Caenorhabditis elegans." Mastwal S.S., Yu D., Hedgecock E.M. Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY314773 mRNA. Translation: AAQ84880.1. Z78013, Z78018 Genomic DNA. Translation: CAB01427.3. Z78018, Z78013 Genomic DNA. Translation: CAB01449.3.
RefSeq	NP_506256.3.
UniGene	Cel.4076
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q19482.
Genome annotation databases
Ensembl	F15B9.7; F15B9.7; F15B9.7; Caenorhabditis elegans. [Genome view]
GeneID	179788.
KEGG	cel:F15B9.7.
NMPDR	fig|6239.3.peg.20182.
UCSC	F15B9.7. c. elegans.
Organism-specific databases
CTD	179788.
WormBase	WBGene00000398. cdh-6.
WormPep	F15B9.7. CE42459. [WorfDB]
Phylogenomic databases
eggNOG	meNOG04518.
HOGENOM	HBG385872.
InParanoid	Q19482.
Gene expression databases
ArrayExpress	Q19482.
Family and domain databases
InterPro	IPR002126. Cadherin. IPR015919. Cadherin-like. IPR020894. Cadherin_CS. IPR008985. ConA-like_lec_gl. IPR013320. ConA-like_subgrp. IPR006210. EGF-like. IPR013032. EGF-like_reg_CS. IPR000742. EGF_3. IPR001881. EGF_Ca_bd. IPR001879. GPCR_2_extracellular_dom. IPR000203. GPS_dom. IPR001791. Laminin_G. IPR012680. Laminin_G_2. [Graphical view]
Gene3D	G3DSA:2.60.40.60. Cadherin. 8 hits. G3DSA:2.60.120.200. ConA_like_subgrp. 2 hits.
Pfam	PF00028. Cadherin. 8 hits. PF02210. Laminin_G_2. 2 hits. [Graphical view]
PRINTS	PR00205. CADHERIN.
SMART	SM00112. CA. 8 hits. SM00181. EGF. 3 hits. SM00179. EGF_CA. 1 hit. SM00303. GPS. 1 hit. SM00008. HormR. 1 hit. SM00282. LamG. 2 hits. [Graphical view]
PROSITE	PS00232. CADHERIN_1. 6 hits. PS50268. CADHERIN_2. 8 hits. PS00022. EGF_1. 4 hits. PS01186. EGF_2. 2 hits. PS50026. EGF_3. 4 hits. PS50227. G_PROTEIN_RECEP_F2_3. 1 hit. PS50221. GPS. 1 hit. PS50025. LAM_G_DOMAIN. 2 hits. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	906860.

Entry information

Entry name

Q19482_CAEEL

Accession

Primary (citable) accession number: Q19482
Secondary accession number(s): Q23218, Q6W3C6

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	April 29, 2008
Last modified:	February 9, 2010
This is version 86 of the entry and version 4 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)