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Protein
Submitted name:

SHaW family of potassium channels

Gene

shw-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Potassium channelSAAS annotation, Voltage-gated channelSAAS annotation
Biological processIon transport, Potassium transport, Transport
LigandPotassium

Enzyme and pathway databases

ReactomeiR-CEL-381676. Glucagon-like Peptide-1 (GLP1) regulates insulin secretion.

Names & Taxonomyi

Protein namesi
Submitted name:
SHaW family of potassium channelsImported
Gene namesi
Name:shw-1Imported
ORF Names:CELE_F14F11.1Imported, F14F11.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiF14F11.1a; CE32375; WBGene00008819; shw-1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei293 – 310HelicalSequence analysisAdd BLAST18
Transmembranei331 – 352HelicalSequence analysisAdd BLAST22
Transmembranei364 – 383HelicalSequence analysisAdd BLAST20
Transmembranei390 – 415HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiWBGene00008819.
ExpressionAtlasiQ19464. baseline.

Interactioni

Protein-protein interaction databases

IntActiQ19464. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliQ19464.
SMRiQ19464.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 105BTBInterPro annotationAdd BLAST101

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118846.
HOGENOMiHOG000231012.
OrthoDBiEOG091G0EJL.

Family and domain databases

InterProiView protein in InterPro
IPR000210. BTB/POZ_dom.
IPR005821. Ion_trans_dom.
IPR003968. K_chnl_volt-dep_Kv.
IPR003974. K_chnl_volt-dep_Kv3.
IPR011333. SKP1/BTB/POZ_sf.
IPR003131. T1-type_BTB.
IPR028325. VG_K_chnl.
PANTHERiPTHR11537. PTHR11537. 1 hit.
PfamiView protein in Pfam
PF02214. BTB_2. 1 hit.
PF00520. Ion_trans. 1 hit.
PRINTSiPR00169. KCHANNEL.
PR01491. KVCHANNEL.
PR01498. SHAWCHANNEL.
SMARTiView protein in SMART
SM00225. BTB. 1 hit.
SUPFAMiSSF54695. SSF54695. 1 hit.

Sequencei

Sequence statusi: Complete.

Q19464-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTEHRVILN VGGIRHETYS HVLKKIPATR LSRLTPNLAN YDPVLNEYFF
60 70 80 90 100
DRHPGVFSMI LNYYRTGKLH YPTNVCGPLF EEELEFWGLD ANQVEPCCWM
110 120 130 140 150
TYTQHRDTQD TLAVIESLDL DGDPPTQEEI AKKFGWEDDY YTGNMSQWQR
160 170 180 190 200
LKPRVWALFD EPWSSKYARV ISSLSVAFIL ASTCSFILKT DPSFQIPDID
210 220 230 240 250
VFYSLRVVDE GGFKNYHKTI GTDKPVTSPH PNFFYVDLIC NIWFTIELLI
260 270 280 290 300
RSLFCPSFHK FVRSPLTIID VISTGAFFFE SLLHAILIQT GSLVTLDFLS
310 320 330 340 350
MICVLRLFKL TQHFSGLKIL IQTFKASAQE LFLLVFFVIL AIVIFAALVY
360 370 380 390 400
YAERSQLNKD NQFTSIPLGL WWSLVTISTV GFGDMVPKTY LGMLVGSLCA
410 420 430 440 450
LMGVLTIALP VPVIVSNFSN LYSHSQARAK LPKKRRRVLQ AHEVKPALLG
460 470 480 490
VKQHHGKHRK KSSSATFNQP PANFKNANGG PSMHDNSASK LMA
Length:493
Mass (Da):55,981
Last modified:March 1, 2003 - v2
Checksum:iDE965A6686D55443
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CAA91092.2.
PIRiT20896.
RefSeqiNP_495752.2. NM_063351.4.
UniGeneiCel.21308.

Genome annotation databases

EnsemblMetazoaiF14F11.1a; F14F11.1a; WBGene00008819.
GeneIDi174331.
UCSCiF14F11.1h. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ19464_CAEEL
AccessioniPrimary (citable) accession number: Q19464
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: March 1, 2003
Last modified: November 22, 2017
This is version 145 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported