Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

SHaW family of potassium channels

Gene

shw-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Potassium channelSAAS annotation, Voltage-gated channelSAAS annotation
Biological processIon transport, Potassium transport, Transport
LigandPotassium

Enzyme and pathway databases

ReactomeiR-CEL-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion

Names & Taxonomyi

Protein namesi
Submitted name:
SHaW family of potassium channelsImported
Gene namesi
Name:shw-1Imported
ORF Names:CELE_F14F11.1Imported, F14F11.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiF14F11.1a ; CE32375 ; WBGene00008819 ; shw-1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei293 – 310HelicalSequence analysisAdd BLAST18
Transmembranei331 – 352HelicalSequence analysisAdd BLAST22
Transmembranei364 – 383HelicalSequence analysisAdd BLAST20
Transmembranei390 – 415HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiWBGene00008819
ExpressionAtlasiQ19464 baseline

Interactioni

Protein-protein interaction databases

IntActiQ19464 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliQ19464
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 105BTBInterPro annotationAdd BLAST101

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118846
HOGENOMiHOG000231012
OrthoDBiEOG091G0EJL

Family and domain databases

Gene3Di1.20.120.3501 hit
InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR005821 Ion_trans_dom
IPR003968 K_chnl_volt-dep_Kv
IPR003974 K_chnl_volt-dep_Kv3
IPR011333 SKP1/BTB/POZ_sf
IPR003131 T1-type_BTB
IPR028325 VG_K_chnl
IPR027359 Volt_channel_dom_sf
PANTHERiPTHR11537 PTHR11537, 1 hit
PfamiView protein in Pfam
PF02214 BTB_2, 1 hit
PF00520 Ion_trans, 1 hit
PRINTSiPR00169 KCHANNEL
PR01491 KVCHANNEL
PR01498 SHAWCHANNEL
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SUPFAMiSSF54695 SSF54695, 1 hit

Sequencei

Sequence statusi: Complete.

Q19464-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTEHRVILN VGGIRHETYS HVLKKIPATR LSRLTPNLAN YDPVLNEYFF
60 70 80 90 100
DRHPGVFSMI LNYYRTGKLH YPTNVCGPLF EEELEFWGLD ANQVEPCCWM
110 120 130 140 150
TYTQHRDTQD TLAVIESLDL DGDPPTQEEI AKKFGWEDDY YTGNMSQWQR
160 170 180 190 200
LKPRVWALFD EPWSSKYARV ISSLSVAFIL ASTCSFILKT DPSFQIPDID
210 220 230 240 250
VFYSLRVVDE GGFKNYHKTI GTDKPVTSPH PNFFYVDLIC NIWFTIELLI
260 270 280 290 300
RSLFCPSFHK FVRSPLTIID VISTGAFFFE SLLHAILIQT GSLVTLDFLS
310 320 330 340 350
MICVLRLFKL TQHFSGLKIL IQTFKASAQE LFLLVFFVIL AIVIFAALVY
360 370 380 390 400
YAERSQLNKD NQFTSIPLGL WWSLVTISTV GFGDMVPKTY LGMLVGSLCA
410 420 430 440 450
LMGVLTIALP VPVIVSNFSN LYSHSQARAK LPKKRRRVLQ AHEVKPALLG
460 470 480 490
VKQHHGKHRK KSSSATFNQP PANFKNANGG PSMHDNSASK LMA
Length:493
Mass (Da):55,981
Last modified:March 1, 2003 - v2
Checksum:iDE965A6686D55443
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA Translation: CAA91092.2
PIRiT20896
RefSeqiNP_495752.2, NM_063351.4
UniGeneiCel.21308

Genome annotation databases

EnsemblMetazoaiF14F11.1a.1; F14F11.1a.1; WBGene00008819
F14F11.1a.2; F14F11.1a.2; WBGene00008819
GeneIDi174331
UCSCiF14F11.1h c. elegans

Similar proteinsi

Entry informationi

Entry nameiQ19464_CAEEL
AccessioniPrimary (citable) accession number: Q19464
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: March 1, 2003
Last modified: April 25, 2018
This is version 148 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported