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Protein
Submitted name:

SHaW family of potassium channels

Gene

shw-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Potassium channelSAAS annotation, Voltage-gated channelSAAS annotation

Keywords - Biological processi

Ion transport, Potassium transport, Transport

Keywords - Ligandi

Potassium

Enzyme and pathway databases

ReactomeiR-CEL-381676. Glucagon-like Peptide-1 (GLP1) regulates insulin secretion.

Names & Taxonomyi

Protein namesi
Submitted name:
SHaW family of potassium channelsImported
Gene namesi
Name:shw-1Imported
ORF Names:CELE_F14F11.1Imported, F14F11.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiF14F11.1a; CE32375; WBGene00008819; shw-1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei293 – 31018HelicalSequence analysisAdd
BLAST
Transmembranei331 – 35222HelicalSequence analysisAdd
BLAST
Transmembranei364 – 38320HelicalSequence analysisAdd
BLAST
Transmembranei390 – 41526HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiWBGene00008819.
ExpressionAtlasiQ19464. baseline.

Interactioni

Protein-protein interaction databases

IntActiQ19464. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ19464.
SMRiQ19464. Positions 4-422.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 105101BTB (POZ)InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118846.
HOGENOMiHOG000231012.
OrthoDBiEOG091G0EJL.

Family and domain databases

Gene3Di1.20.120.350. 1 hit.
InterProiIPR000210. BTB/POZ_dom.
IPR027359. Channel_four-helix_dom.
IPR005821. Ion_trans_dom.
IPR003968. K_chnl_volt-dep_Kv.
IPR003974. K_chnl_volt-dep_Kv3.
IPR011333. SKP1/BTB/POZ.
IPR003131. T1-type_BTB.
IPR028325. VG_K_chnl.
[Graphical view]
PANTHERiPTHR11537. PTHR11537. 1 hit.
PfamiPF02214. BTB_2. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR00169. KCHANNEL.
PR01491. KVCHANNEL.
PR01498. SHAWCHANNEL.
SMARTiSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.

Sequencei

Sequence statusi: Complete.

Q19464-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTEHRVILN VGGIRHETYS HVLKKIPATR LSRLTPNLAN YDPVLNEYFF
60 70 80 90 100
DRHPGVFSMI LNYYRTGKLH YPTNVCGPLF EEELEFWGLD ANQVEPCCWM
110 120 130 140 150
TYTQHRDTQD TLAVIESLDL DGDPPTQEEI AKKFGWEDDY YTGNMSQWQR
160 170 180 190 200
LKPRVWALFD EPWSSKYARV ISSLSVAFIL ASTCSFILKT DPSFQIPDID
210 220 230 240 250
VFYSLRVVDE GGFKNYHKTI GTDKPVTSPH PNFFYVDLIC NIWFTIELLI
260 270 280 290 300
RSLFCPSFHK FVRSPLTIID VISTGAFFFE SLLHAILIQT GSLVTLDFLS
310 320 330 340 350
MICVLRLFKL TQHFSGLKIL IQTFKASAQE LFLLVFFVIL AIVIFAALVY
360 370 380 390 400
YAERSQLNKD NQFTSIPLGL WWSLVTISTV GFGDMVPKTY LGMLVGSLCA
410 420 430 440 450
LMGVLTIALP VPVIVSNFSN LYSHSQARAK LPKKRRRVLQ AHEVKPALLG
460 470 480 490
VKQHHGKHRK KSSSATFNQP PANFKNANGG PSMHDNSASK LMA
Length:493
Mass (Da):55,981
Last modified:March 1, 2003 - v2
Checksum:iDE965A6686D55443
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CAA91092.2.
PIRiT20896.
RefSeqiNP_495752.2. NM_063351.4.
UniGeneiCel.21308.

Genome annotation databases

EnsemblMetazoaiF14F11.1a; F14F11.1a; WBGene00008819.
GeneIDi174331.
UCSCiF14F11.1h. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CAA91092.2.
PIRiT20896.
RefSeqiNP_495752.2. NM_063351.4.
UniGeneiCel.21308.

3D structure databases

ProteinModelPortaliQ19464.
SMRiQ19464. Positions 4-422.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ19464. 1 interaction.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF14F11.1a; F14F11.1a; WBGene00008819.
GeneIDi174331.
UCSCiF14F11.1h. c. elegans.

Organism-specific databases

CTDi174331.
WormBaseiF14F11.1a; CE32375; WBGene00008819; shw-1.

Phylogenomic databases

GeneTreeiENSGT00760000118846.
HOGENOMiHOG000231012.
OrthoDBiEOG091G0EJL.

Enzyme and pathway databases

ReactomeiR-CEL-381676. Glucagon-like Peptide-1 (GLP1) regulates insulin secretion.

Gene expression databases

BgeeiWBGene00008819.
ExpressionAtlasiQ19464. baseline.

Family and domain databases

Gene3Di1.20.120.350. 1 hit.
InterProiIPR000210. BTB/POZ_dom.
IPR027359. Channel_four-helix_dom.
IPR005821. Ion_trans_dom.
IPR003968. K_chnl_volt-dep_Kv.
IPR003974. K_chnl_volt-dep_Kv3.
IPR011333. SKP1/BTB/POZ.
IPR003131. T1-type_BTB.
IPR028325. VG_K_chnl.
[Graphical view]
PANTHERiPTHR11537. PTHR11537. 1 hit.
PfamiPF02214. BTB_2. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR00169. KCHANNEL.
PR01491. KVCHANNEL.
PR01498. SHAWCHANNEL.
SMARTiSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ19464_CAEEL
AccessioniPrimary (citable) accession number: Q19464
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: March 1, 2003
Last modified: September 7, 2016
This is version 133 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.