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Q19440

- Q19440_CAEEL

UniProt

Q19440 - Q19440_CAEEL

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Protein
Submitted name:

Protein F14B4.2, isoform a

Gene

CELE_F14B4.2

Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. fructokinase activity Source: RefGenome
  3. glucokinase activity Source: RefGenome
  4. mannokinase activity Source: RefGenome

GO - Biological processi

  1. carbohydrate phosphorylation Source: GOC
  2. cellular glucose homeostasis Source: RefGenome
  3. glucose 6-phosphate metabolic process Source: GOC
  4. glycolytic process Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Protein F14B4.2, isoform aImported
Gene namesi
ORF Names:CELE_F14B4.2Imported, F14B4.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome I

Organism-specific databases

WormBaseiF14B4.2a; CE05628; WBGene00008780.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: RefGenome
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ19440.
PRIDEiQ19440.

Expressioni

Gene expression databases

ExpressionAtlasiQ19440. baseline.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CELE_ZK829.7Q236243EBI-319585,EBI-315971

Protein-protein interaction databases

DIPiDIP-26887N.
IntActiQ19440. 1 interaction.
MINTiMINT-1129380.
STRINGi6239.F14B4.2a.2.

Structurei

3D structure databases

ProteinModelPortaliQ19440.
SMRiQ19440. Positions 37-490.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG5026.
GeneTreeiENSGT00390000017159.
HOGENOMiHOG000162670.
InParanoidiQ19440.
KOiK00844.
OMAiPVIINME.
PhylomeDBiQ19440.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q19440-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSSIVCHPIL DSQNGIATDA VIKKQRPPPL VLSRPKDLIQ EACQRLVLSD
60 70 80 90 100
QQLRRIMQSM EKSMEQGLAT STKKVAVKML PTYVDSVPNG TESGDFLALD
110 120 130 140 150
LGGTNFRVLH IKLQGKETKM TGKIFRVPES IMRGTGEALF DHIAGCMAKF
160 170 180 190 200
MGENDLKDAQ KLPLGFTFSF PCEQEGLTKG KLVTWTKGFK ASGVEGVDVV
210 220 230 240 250
TLLHEACHRR KDIDIDVVAL LNDTVGTLMA CAFQENSCQI GVIVGTGTNA
260 270 280 290 300
CYMERLDRIP KLAGYVDEHG VTPEEMIINT EWGAFGDDGA LDFLRTEWDE
310 320 330 340 350
VVDRESINPG QHLYEKMISG MYMGECARVV LEDLAKQGLL FGGNSDAISV
360 370 380 390 400
PHCFPTKFVS EIDSDLLEDD DRTFQKTYQI LEDIGVEMIT ANDCANVAYV
410 420 430 440 450
CSLISTRAAH LTAAGIAMLL NRMNKKHVTV GVDGSVYRFH PTYPTLLDAK
460 470 480 490 500
IGELIVGDIE YKLMLSEDGS GRGAALVAAV ATRLKEEKLA ASLSSSSSNQ
Length:500
Mass (Da):54,670
Last modified:November 1, 1996 - v1
Checksum:i446EF1799DFAFEC2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z75535 Genomic DNA. Translation: CAA99826.1.
PIRiT20869.
RefSeqiNP_001021106.1. NM_001025935.2.
UniGeneiCel.7424.

Genome annotation databases

EnsemblMetazoaiF14B4.2a; F14B4.2a; WBGene00008780.
GeneIDi172751.
KEGGicel:CELE_F14B4.2.
UCSCiF14B4.2b. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z75535 Genomic DNA. Translation: CAA99826.1 .
PIRi T20869.
RefSeqi NP_001021106.1. NM_001025935.2.
UniGenei Cel.7424.

3D structure databases

ProteinModelPortali Q19440.
SMRi Q19440. Positions 37-490.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-26887N.
IntActi Q19440. 1 interaction.
MINTi MINT-1129380.
STRINGi 6239.F14B4.2a.2.

Proteomic databases

PaxDbi Q19440.
PRIDEi Q19440.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai F14B4.2a ; F14B4.2a ; WBGene00008780 .
GeneIDi 172751.
KEGGi cel:CELE_F14B4.2.
UCSCi F14B4.2b. c. elegans.

Organism-specific databases

CTDi 172751.
WormBasei F14B4.2a ; CE05628 ; WBGene00008780 .

Phylogenomic databases

eggNOGi COG5026.
GeneTreei ENSGT00390000017159.
HOGENOMi HOG000162670.
InParanoidi Q19440.
KOi K00844.
OMAi PVIINME.
PhylomeDBi Q19440.

Miscellaneous databases

NextBioi 876865.

Gene expression databases

ExpressionAtlasi Q19440. baseline.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
PROSITEi PS00378. HEXOKINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ19440_CAEEL
AccessioniPrimary (citable) accession number: Q19440
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3