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Q19440

- Q19440_CAEEL

UniProt

Q19440 - Q19440_CAEEL

Protein
Submitted name:

Protein F14B4.2, isoform a

Gene

CELE_F14B4.2

Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 107 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. fructokinase activity Source: RefGenome
    3. glucokinase activity Source: RefGenome
    4. mannokinase activity Source: RefGenome
    5. protein binding Source: IntAct

    GO - Biological processi

    1. carbohydrate phosphorylation Source: GOC
    2. cellular glucose homeostasis Source: RefGenome
    3. glucose 6-phosphate metabolic process Source: GOC
    4. glycolytic process Source: RefGenome

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotation, Transferase

    Keywords - Biological processi

    GlycolysisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein F14B4.2, isoform aImported
    Gene namesi
    ORF Names:CELE_F14B4.2Imported, F14B4.2Imported
    OrganismiCaenorhabditis elegansImported
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome I

    Organism-specific databases

    WormBaseiF14B4.2a; CE05628; WBGene00008780.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: RefGenome

    PTM / Processingi

    Proteomic databases

    PaxDbiQ19440.
    PRIDEiQ19440.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    CELE_ZK829.7Q236243EBI-319585,EBI-315971

    Protein-protein interaction databases

    DIPiDIP-26887N.
    IntActiQ19440. 1 interaction.
    MINTiMINT-1129380.
    STRINGi6239.F14B4.2a.2.

    Structurei

    3D structure databases

    ProteinModelPortaliQ19440.
    SMRiQ19440. Positions 37-490.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the hexokinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG5026.
    GeneTreeiENSGT00390000017159.
    HOGENOMiHOG000162670.
    InParanoidiQ19440.
    KOiK00844.
    OMAiPVIINME.
    PhylomeDBiQ19440.

    Family and domain databases

    InterProiIPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR019807. Hexokinase_CS.
    IPR022672. Hexokinase_N.
    [Graphical view]
    PANTHERiPTHR19443. PTHR19443. 1 hit.
    PfamiPF00349. Hexokinase_1. 1 hit.
    PF03727. Hexokinase_2. 1 hit.
    [Graphical view]
    PRINTSiPR00475. HEXOKINASE.
    PROSITEiPS00378. HEXOKINASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q19440-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSIVCHPIL DSQNGIATDA VIKKQRPPPL VLSRPKDLIQ EACQRLVLSD    50
    QQLRRIMQSM EKSMEQGLAT STKKVAVKML PTYVDSVPNG TESGDFLALD 100
    LGGTNFRVLH IKLQGKETKM TGKIFRVPES IMRGTGEALF DHIAGCMAKF 150
    MGENDLKDAQ KLPLGFTFSF PCEQEGLTKG KLVTWTKGFK ASGVEGVDVV 200
    TLLHEACHRR KDIDIDVVAL LNDTVGTLMA CAFQENSCQI GVIVGTGTNA 250
    CYMERLDRIP KLAGYVDEHG VTPEEMIINT EWGAFGDDGA LDFLRTEWDE 300
    VVDRESINPG QHLYEKMISG MYMGECARVV LEDLAKQGLL FGGNSDAISV 350
    PHCFPTKFVS EIDSDLLEDD DRTFQKTYQI LEDIGVEMIT ANDCANVAYV 400
    CSLISTRAAH LTAAGIAMLL NRMNKKHVTV GVDGSVYRFH PTYPTLLDAK 450
    IGELIVGDIE YKLMLSEDGS GRGAALVAAV ATRLKEEKLA ASLSSSSSNQ 500
    Length:500
    Mass (Da):54,670
    Last modified:November 1, 1996 - v1
    Checksum:i446EF1799DFAFEC2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z75535 Genomic DNA. Translation: CAA99826.1.
    PIRiT20869.
    RefSeqiNP_001021106.1. NM_001025935.2.
    UniGeneiCel.7424.

    Genome annotation databases

    EnsemblMetazoaiF14B4.2a; F14B4.2a; WBGene00008780.
    GeneIDi172751.
    KEGGicel:CELE_F14B4.2.
    UCSCiF14B4.2b. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z75535 Genomic DNA. Translation: CAA99826.1 .
    PIRi T20869.
    RefSeqi NP_001021106.1. NM_001025935.2.
    UniGenei Cel.7424.

    3D structure databases

    ProteinModelPortali Q19440.
    SMRi Q19440. Positions 37-490.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-26887N.
    IntActi Q19440. 1 interaction.
    MINTi MINT-1129380.
    STRINGi 6239.F14B4.2a.2.

    Proteomic databases

    PaxDbi Q19440.
    PRIDEi Q19440.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai F14B4.2a ; F14B4.2a ; WBGene00008780 .
    GeneIDi 172751.
    KEGGi cel:CELE_F14B4.2.
    UCSCi F14B4.2b. c. elegans.

    Organism-specific databases

    CTDi 172751.
    WormBasei F14B4.2a ; CE05628 ; WBGene00008780 .

    Phylogenomic databases

    eggNOGi COG5026.
    GeneTreei ENSGT00390000017159.
    HOGENOMi HOG000162670.
    InParanoidi Q19440.
    KOi K00844.
    OMAi PVIINME.
    PhylomeDBi Q19440.

    Miscellaneous databases

    NextBioi 876865.

    Family and domain databases

    InterProi IPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR019807. Hexokinase_CS.
    IPR022672. Hexokinase_N.
    [Graphical view ]
    PANTHERi PTHR19443. PTHR19443. 1 hit.
    Pfami PF00349. Hexokinase_1. 1 hit.
    PF03727. Hexokinase_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00475. HEXOKINASE.
    PROSITEi PS00378. HEXOKINASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2Imported.

    Entry informationi

    Entry nameiQ19440_CAEEL
    AccessioniPrimary (citable) accession number: Q19440
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1996
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 107 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3