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Protein

Phosphotransferase

Gene

hxk-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotation, Transferase
Biological processGlycolysisUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-CEL-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein
R-CEL-6798695 Neutrophil degranulation
R-CEL-70171 Glycolysis

Names & Taxonomyi

Protein namesi
Recommended name:
PhosphotransferaseUniRule annotation (EC:2.7.1.-UniRule annotation)
Gene namesi
Name:hxk-1Imported
ORF Names:CELE_F14B4.2Imported, F14B4.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiF14B4.2a ; CE05628 ; WBGene00008780 ; hxk-1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

EPDiQ19440
PaxDbiQ19440
PeptideAtlasiQ19440

Expressioni

Gene expression databases

BgeeiWBGene00008780
ExpressionAtlasiQ19440 baseline and differential

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CELE_ZK829.7Q236243EBI-319585,EBI-315971

Protein-protein interaction databases

DIPiDIP-26887N
IntActiQ19440, 1 interactor
STRINGi6239.F14B4.2a.2

Structurei

3D structure databases

ProteinModelPortaliQ19440
SMRiQ19440
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 233Hexokinase_1InterPro annotationAdd BLAST195
Domaini239 – 480Hexokinase_2InterPro annotationAdd BLAST242

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1369 Eukaryota
COG5026 LUCA
GeneTreeiENSGT00390000017159
HOGENOMiHOG000162670
InParanoidiQ19440
OMAiMIPTFVT
OrthoDBiEOG091G08MD
PhylomeDBiQ19440

Family and domain databases

InterProiView protein in InterPro
IPR001312 Hexokinase
IPR019807 Hexokinase_BS
IPR022673 Hexokinase_C
IPR022672 Hexokinase_N
PANTHERiPTHR19443 PTHR19443, 1 hit
PfamiView protein in Pfam
PF00349 Hexokinase_1, 1 hit
PF03727 Hexokinase_2, 1 hit
PROSITEiView protein in PROSITE
PS00378 HEXOKINASE_1, 1 hit
PS51748 HEXOKINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q19440-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSIVCHPIL DSQNGIATDA VIKKQRPPPL VLSRPKDLIQ EACQRLVLSD
60 70 80 90 100
QQLRRIMQSM EKSMEQGLAT STKKVAVKML PTYVDSVPNG TESGDFLALD
110 120 130 140 150
LGGTNFRVLH IKLQGKETKM TGKIFRVPES IMRGTGEALF DHIAGCMAKF
160 170 180 190 200
MGENDLKDAQ KLPLGFTFSF PCEQEGLTKG KLVTWTKGFK ASGVEGVDVV
210 220 230 240 250
TLLHEACHRR KDIDIDVVAL LNDTVGTLMA CAFQENSCQI GVIVGTGTNA
260 270 280 290 300
CYMERLDRIP KLAGYVDEHG VTPEEMIINT EWGAFGDDGA LDFLRTEWDE
310 320 330 340 350
VVDRESINPG QHLYEKMISG MYMGECARVV LEDLAKQGLL FGGNSDAISV
360 370 380 390 400
PHCFPTKFVS EIDSDLLEDD DRTFQKTYQI LEDIGVEMIT ANDCANVAYV
410 420 430 440 450
CSLISTRAAH LTAAGIAMLL NRMNKKHVTV GVDGSVYRFH PTYPTLLDAK
460 470 480 490 500
IGELIVGDIE YKLMLSEDGS GRGAALVAAV ATRLKEEKLA ASLSSSSSNQ
Length:500
Mass (Da):54,670
Last modified:November 1, 1996 - v1
Checksum:i446EF1799DFAFEC2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CAA99826.1
PIRiT20869
RefSeqiNP_001021106.1, NM_001025935.2
UniGeneiCel.7424

Genome annotation databases

EnsemblMetazoaiF14B4.2a.1; F14B4.2a.1; WBGene00008780
F14B4.2a.2; F14B4.2a.2; WBGene00008780
GeneIDi172751
UCSCiF14B4.2b c. elegans

Similar proteinsi

Entry informationi

Entry nameiQ19440_CAEEL
AccessioniPrimary (citable) accession number: Q19440
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: February 28, 2018
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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