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Protein
Submitted name:

Proteasome Regulatory Particle, Non-ATPase-like

Gene

rpn-5

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CEL-1234176. Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha.
R-CEL-1236978. Cross-presentation of soluble exogenous antigens (endosomes).
R-CEL-195253. Degradation of beta-catenin by the destruction complex.
R-CEL-382556. ABC-family proteins mediated transport.
R-CEL-4608870. Asymmetric localization of PCP proteins.
R-CEL-4641258. Degradation of DVL.
R-CEL-5632684. Hedgehog 'on' state.
R-CEL-5689603. UCH proteinases.
R-CEL-5689880. Ub-specific processing proteases.
R-CEL-6798695. Neutrophil degranulation.
R-CEL-68949. Orc1 removal from chromatin.
R-CEL-69229. Ubiquitin-dependent degradation of Cyclin D1.
R-CEL-69601. Ubiquitin Mediated Degradation of Phosphorylated Cdc25A.
R-CEL-8941858. Regulation of RUNX3 expression and activity.
R-CEL-983168. Antigen processing: Ubiquitination & Proteasome degradation.

Names & Taxonomyi

Protein namesi
Submitted name:
Proteasome Regulatory Particle, Non-ATPase-likeImported
Gene namesi
Name:rpn-5Imported
ORF Names:CELE_F10G7.8Imported, F10G7.8Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiF10G7.8; CE02632; WBGene00004461; rpn-5.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

ProteasomeImported

PTM / Processingi

Proteomic databases

EPDiQ19324.
PaxDbiQ19324.
PeptideAtlasiQ19324.

Expressioni

Gene expression databases

BgeeiWBGene00004461.

Interactioni

Protein-protein interaction databases

STRINGi6239.F10G7.8.3.

Structurei

3D structure databases

ProteinModelPortaliQ19324.
SMRiQ19324.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini375 – 462PCIInterPro annotationAdd BLAST88

Phylogenomic databases

eggNOGiKOG1498. Eukaryota.
COG5071. LUCA.
GeneTreeiENSGT00730000111110.
HOGENOMiHOG000194265.
InParanoidiQ19324.
KOiK03035.
OMAiKQAITKM.
OrthoDBiEOG091G06CB.
PhylomeDBiQ19324.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR000717. PCI_dom.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF01399. PCI. 1 hit.
SMARTiView protein in SMART
SM00088. PINT. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.

Sequencei

Sequence statusi: Complete.

Q19324-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADRREPIPV DPVDVGELSE LDNLAHLAAH GGDGRLFKME QDYSKQVDEA
60 70 80 90 100
LLKARDIAQK DAVAAVESLN NIEKLTRLGA DMKSNTRVVQ YMTKLCFEGQ
110 120 130 140 150
KWDLLMETIM TLSKKRLLIK MAIAKMVRDA VAMIDKMPTE DLKMKLIETL
160 170 180 190 200
RTVTAGKIYV EVERARLTSM VVKKLEREGK LDEAATMLLE LQVETYGSME
210 220 230 240 250
MREKVQYLLE QMRYSLVRND FVRATIISKK INIKFFNKSD EDEVQNLKLK
260 270 280 290 300
YYDSMIRIGL HDGNYLDVCR HHREIYETKK IKADSAKATS HLRSAIVYCL
310 320 330 340 350
LAPHTNEQWD LLNRIAIQRE LETVPDYKII LDLFINQELI SFKGTIVAKY
360 370 380 390 400
EKLLRRGTTS SPDTGIFDKS TEGEKRWSDL HLRVGEHNMR MIAKYYTQIT
410 420 430 440 450
FERLAELLDF PVDEMESFVC NLIVTGQITG AKLHRPSRIV NLRLKKANVE
460 470 480 490
QLDVWASNVH KLTDTLNKVS HLILKEQMVH KNLDLAAPRA
Length:490
Mass (Da):56,457
Last modified:November 1, 1996 - v1
Checksum:i93F456ACEE888949
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CCD69211.1.
PIRiF88130.
RefSeqiNP_494835.1. NM_062434.3.
UniGeneiCel.6606.

Genome annotation databases

EnsemblMetazoaiF10G7.8.1; F10G7.8.1; WBGene00004461.
F10G7.8.2; F10G7.8.2; WBGene00004461.
GeneIDi173807.
KEGGicel:CELE_F10G7.8.
UCSCiF10G7.8.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CCD69211.1.
PIRiF88130.
RefSeqiNP_494835.1. NM_062434.3.
UniGeneiCel.6606.

3D structure databases

ProteinModelPortaliQ19324.
SMRiQ19324.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F10G7.8.3.

Proteomic databases

EPDiQ19324.
PaxDbiQ19324.
PeptideAtlasiQ19324.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF10G7.8.1; F10G7.8.1; WBGene00004461.
F10G7.8.2; F10G7.8.2; WBGene00004461.
GeneIDi173807.
KEGGicel:CELE_F10G7.8.
UCSCiF10G7.8.1. c. elegans.

Organism-specific databases

CTDi173807.
WormBaseiF10G7.8; CE02632; WBGene00004461; rpn-5.

Phylogenomic databases

eggNOGiKOG1498. Eukaryota.
COG5071. LUCA.
GeneTreeiENSGT00730000111110.
HOGENOMiHOG000194265.
InParanoidiQ19324.
KOiK03035.
OMAiKQAITKM.
OrthoDBiEOG091G06CB.
PhylomeDBiQ19324.

Enzyme and pathway databases

ReactomeiR-CEL-1234176. Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha.
R-CEL-1236978. Cross-presentation of soluble exogenous antigens (endosomes).
R-CEL-195253. Degradation of beta-catenin by the destruction complex.
R-CEL-382556. ABC-family proteins mediated transport.
R-CEL-4608870. Asymmetric localization of PCP proteins.
R-CEL-4641258. Degradation of DVL.
R-CEL-5632684. Hedgehog 'on' state.
R-CEL-5689603. UCH proteinases.
R-CEL-5689880. Ub-specific processing proteases.
R-CEL-6798695. Neutrophil degranulation.
R-CEL-68949. Orc1 removal from chromatin.
R-CEL-69229. Ubiquitin-dependent degradation of Cyclin D1.
R-CEL-69601. Ubiquitin Mediated Degradation of Phosphorylated Cdc25A.
R-CEL-8941858. Regulation of RUNX3 expression and activity.
R-CEL-983168. Antigen processing: Ubiquitination & Proteasome degradation.

Gene expression databases

BgeeiWBGene00004461.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR000717. PCI_dom.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF01399. PCI. 1 hit.
SMARTiView protein in SMART
SM00088. PINT. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ19324_CAEEL
AccessioniPrimary (citable) accession number: Q19324
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 7, 2017
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.