Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

SPONdin (Extracellular matrix glycoprotein) family

Gene

spon-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • axonal fasciculation Source: WormBase
  • cell adhesion mediated by integrin Source: WormBase
  • dorsal/ventral axon guidance Source: WormBase
  • motor neuron axon guidance Source: WormBase
  • muscle attachment Source: WormBase
Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-CEL-5173214. O-glycosylation of TSR domain-containing proteins.

Names & Taxonomyi

Protein namesi
Submitted name:
SPONdin (Extracellular matrix glycoprotein) familyImported
Gene namesi
Name:spon-1Imported
ORF Names:CELE_F10E7.4Imported, F10E7.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiF10E7.4; CE32368; WBGene00006893; spon-1.

Subcellular locationi

GO - Cellular componenti

  • basement membrane Source: WormBase
  • M band Source: WormBase
  • striated muscle dense body Source: WormBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500418711323 – 819Sequence analysisAdd BLAST797

Proteomic databases

EPDiQ19305.
PaxDbiQ19305.
PeptideAtlasiQ19305.

Expressioni

Gene expression databases

BgeeiWBGene00006893.

Interactioni

Protein-protein interaction databases

STRINGi6239.F10E7.4.

Structurei

3D structure databases

ProteinModelPortaliQ19305.
SMRiQ19305.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 187ReelinInterPro annotationAdd BLAST176
Domaini187 – 378SpondinInterPro annotationAdd BLAST192
Domaini622 – 672BPTI/Kunitz inhibitorInterPro annotationAdd BLAST51

Sequence similaritiesi

Contains 1 BPTI/Kunitz inhibitor domain.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3539. Eukaryota.
ENOG410XQHP. LUCA.
GeneTreeiENSGT00810000125397.
HOGENOMiHOG000230764.
InParanoidiQ19305.
OMAiFYSEHEK.
OrthoDBiEOG091G02MV.
PhylomeDBiQ19305.

Family and domain databases

CDDicd08544. Reeler. 1 hit.
Gene3Di4.10.410.10. 1 hit.
InterProiIPR002223. Kunitz_BPTI.
IPR020901. Prtase_inh_Kunz-CS.
IPR002861. Reeler_dom.
IPR009465. Spondin_N.
IPR000884. TSP1_rpt.
[Graphical view]
PfamiPF00014. Kunitz_BPTI. 1 hit.
PF02014. Reeler. 1 hit.
PF06468. Spond_N. 1 hit.
PF00090. TSP_1. 5 hits.
[Graphical view]
PRINTSiPR00759. BASICPTASE.
SMARTiSM00131. KU. 1 hit.
SM00209. TSP1. 5 hits.
[Graphical view]
SUPFAMiSSF57362. SSF57362. 1 hit.
SSF82895. SSF82895. 5 hits.
PROSITEiPS00280. BPTI_KUNITZ_1. 1 hit.
PS50279. BPTI_KUNITZ_2. 1 hit.
PS51019. REELIN. 1 hit.
PS51020. SPONDIN. 1 hit.
PS50092. TSP1. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q19305-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRFVAILQF ILLLLLIFSC NADEAKCTIK PYEAKGDKSP GSNGYVIEIN
60 70 80 90 100
GTTTKSMDIS KGFVPGEIYK VSIRGWRTQY TVKTFRGFVV SSLFEDNTSA
110 120 130 140 150
GSWQVVKGHG DARISPGCRQ SGVSHANLKS KTSVHMMWKA PEVSSGCVVF
160 170 180 190 200
RASVIETKYI WFTEAEGLTV KLCIQKGTQI LKPVDDPSAT CCACDIAQYD
210 220 230 240 250
LEFTGIWSKN THPKDYPTLE HLTHFTDMLG SSHSSNYSLW TIGGISTDGM
260 270 280 290 300
KEIAEWGNTY KAEAEAKAKA SEVRSLMKVK GLWFPDVQGT TKSQFVVNKY
310 320 330 340 350
HHFVSLATMF GPSPDWCVGL SSVNLCLPDC TWAEERTFEL QPFDAGTDSG
360 370 380 390 400
PTYMSPNEPT EPREPIHWIT TKLNPLSPFY NSKSDTIPTL AKVILRRKNV
410 420 430 440 450
TSSECKSDDI LKAEAHNITN TSEDEEYKDR RECMMTQWEP WSLCSATCGK
460 470 480 490 500
GIRIRSRVYV FPIKAQVFHC HRQTTEKQFC NAKINECENS EAFSSKCQVS
510 520 530 540 550
SWGSWGECSV QCGHGMRSRN RTFLNPATKS GDCSVDLERK DICVGENGDD
560 570 580 590 600
CNVTPDPLCK TTAWSDWSPC SASCDEGVRV RTRLFFYSEH EKRCMHVNLQ
610 620 630 640 650
EKDTCVMQSC RRFIEINSEE ICQEDKQAGQ CAGNFPRYWY NHEKTQCERF
660 670 680 690 700
IFTGCKGNRN QFETEEECKQ ICLPGYEKSK SLIPNNQLLE DFGNTEVDDG
710 720 730 740 750
GERVDCEVSK WTAWGSCSVS CGRGKKSRSR HVVKLARNGG HQCSEHLMQE
760 770 780 790 800
LQCRLRPCPV KLTCQVGPWS RWSPCSVSCG EGSQTRRRRV VRARNDDWEE
810
IECDDAETEV RQCTGRHQC
Length:819
Mass (Da):92,419
Last modified:March 1, 2003 - v2
Checksum:iCC9B18DB872A2C35
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CCD69166.1.
PIRiT34212.
RefSeqiNP_495473.2. NM_063072.7.
UniGeneiCel.34220.

Genome annotation databases

EnsemblMetazoaiF10E7.4; F10E7.4; WBGene00006893.
GeneIDi174169.
KEGGicel:CELE_F10E7.4.
UCSCiF10E7.4. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CCD69166.1.
PIRiT34212.
RefSeqiNP_495473.2. NM_063072.7.
UniGeneiCel.34220.

3D structure databases

ProteinModelPortaliQ19305.
SMRiQ19305.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F10E7.4.

Proteomic databases

EPDiQ19305.
PaxDbiQ19305.
PeptideAtlasiQ19305.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF10E7.4; F10E7.4; WBGene00006893.
GeneIDi174169.
KEGGicel:CELE_F10E7.4.
UCSCiF10E7.4. c. elegans.

Organism-specific databases

CTDi174169.
WormBaseiF10E7.4; CE32368; WBGene00006893; spon-1.

Phylogenomic databases

eggNOGiKOG3539. Eukaryota.
ENOG410XQHP. LUCA.
GeneTreeiENSGT00810000125397.
HOGENOMiHOG000230764.
InParanoidiQ19305.
OMAiFYSEHEK.
OrthoDBiEOG091G02MV.
PhylomeDBiQ19305.

Enzyme and pathway databases

ReactomeiR-CEL-5173214. O-glycosylation of TSR domain-containing proteins.

Miscellaneous databases

PROiQ19305.

Gene expression databases

BgeeiWBGene00006893.

Family and domain databases

CDDicd08544. Reeler. 1 hit.
Gene3Di4.10.410.10. 1 hit.
InterProiIPR002223. Kunitz_BPTI.
IPR020901. Prtase_inh_Kunz-CS.
IPR002861. Reeler_dom.
IPR009465. Spondin_N.
IPR000884. TSP1_rpt.
[Graphical view]
PfamiPF00014. Kunitz_BPTI. 1 hit.
PF02014. Reeler. 1 hit.
PF06468. Spond_N. 1 hit.
PF00090. TSP_1. 5 hits.
[Graphical view]
PRINTSiPR00759. BASICPTASE.
SMARTiSM00131. KU. 1 hit.
SM00209. TSP1. 5 hits.
[Graphical view]
SUPFAMiSSF57362. SSF57362. 1 hit.
SSF82895. SSF82895. 5 hits.
PROSITEiPS00280. BPTI_KUNITZ_1. 1 hit.
PS50279. BPTI_KUNITZ_2. 1 hit.
PS51019. REELIN. 1 hit.
PS51020. SPONDIN. 1 hit.
PS50092. TSP1. 4 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ19305_CAEEL
AccessioniPrimary (citable) accession number: Q19305
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: March 1, 2003
Last modified: November 2, 2016
This is version 124 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.