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Protein
Submitted name:

SKI (Yeast SuperKIller) Helicase homolog

Gene

skih-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-CEL-429958. mRNA decay by 3' to 5' exoribonuclease.

Names & Taxonomyi

Protein namesi
Submitted name:
SKI (Yeast SuperKIller) Helicase homologImported
Gene namesi
Name:skih-2Imported
ORF Names:CELE_F01G4.3Imported, F01G4.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiF01G4.3; CE40452; WBGene00008502; skih-2.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

EPDiQ19103.
PaxDbiQ19103.
PeptideAtlasiQ19103.

Expressioni

Gene expression databases

BgeeiWBGene00008502.

Interactioni

Protein-protein interaction databases

STRINGi6239.F01G4.3.

Structurei

3D structure databases

ProteinModelPortaliQ19103.
SMRiQ19103.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini301 – 457Helicase ATP-bindingInterPro annotationAdd BLAST157
Domaini586 – 752Helicase C-terminalInterPro annotationAdd BLAST167

Phylogenomic databases

eggNOGiKOG0948. Eukaryota.
COG4581. LUCA.
GeneTreeiENSGT00890000139612.
HOGENOMiHOG000163048.
InParanoidiQ19103.
KOiK12599.
OMAiTQYPFWP.
OrthoDBiEOG091G0184.
PhylomeDBiQ19103.

Family and domain databases

InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR025696. rRNA_proc-arch_dom.
IPR016438. Ski2.
IPR012961. Ski2_C.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF08148. DSHCT. 1 hit.
PF00271. Helicase_C. 1 hit.
PF13234. rRNA_proc-arch. 1 hit.
PIRSFiPIRSF005198. Antiviral_helicase_SKI2. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM01142. DSHCT. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiView protein in PROSITE
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q19103-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLEEEAERLF RLECLETLNW PPCAPIPFHI TKQNPSAEFY NVADNLDSLL
60 70 80 90 100
QPIDAPANII AQVDSNGKII GFVENERIIV GSANTSMSIN RAPYKQRSLH
110 120 130 140 150
TTAGNSIKGS PGNVPFLPGF LEELDDLLAG ETTAKSTSGE ESKFLSFKDD
160 170 180 190 200
ATLLNTIPTI GQIVLPNHSS VKKPAETPKS INIEEMDMFD LLDMVTSNEY
210 220 230 240 250
IIHTVAAPVK KSESIESEET PEDDKKVSEN EIDEIEIPII PGNTEKVIEI
260 270 280 290 300
FGAATEPTKE KFEFAQRLVL SADEEDEYKR LVPTMARKYP FSLDPFQQSS
310 320 330 340 350
VLCMERGESL FVAAHTSAGK TVVAEYAIAL CQAHKTRAVY TSPIKALSNQ
360 370 380 390 400
KFRDFKQIFG DVGLVTGDIQ LHPEAACLIM TTEILRSMLY NGSEVIRDLE
410 420 430 440 450
WVVFDEVHYI NNEERGHVWE EVLIMLPAHV KIVMLSATVP NCVEFADWVG
460 470 480 490 500
RIKNRKINVI STDRRPVPLE HFLYTGQDGK TQKDLFKIID RSGQFILKGY
510 520 530 540 550
NDAKDSKAKI YEKEKAGGAG GRGTQRGGGR GGGGNGGGRN WPGKNDKNIY
560 570 580 590 600
LNLINYMKCS DQLPMVVFVF SRKRCDENAQ MLASMNLTTE VEKQHVRLFF
610 620 630 640 650
SQCVQRLKGS DKELPQVLTM RDLCLRGFAV HHSGILPILK EVVELLFQKG
660 670 680 690 700
YVKILFATET FAMGVNMPAR CVVFDSIMKH DGTERRMLNP GEYTQMAGRA
710 720 730 740 750
GRRGLDLTGT VIIICKDSTV PQPDVLKNLI SGQALRLESK FRVTYSMILN
760 770 780 790 800
LLRVEQLKIE DMLQRSYVES DSLRESKEKR KSLVDTKNAI QTMSTIECST
810 820 830 840 850
CSPNSQLRDY HDALAVFLRK SEHIWPKLND ENVINKLLCS GRFLIVNSAQ
860 870 880 890 900
QQLQNECVLL IKELNNKTLQ ILVASADADE TTNKNAAAIG FSKLPKSELS
910 920 930 940 950
WLTEENSLLS TSKFGTRGAA HCSTNIRSFR LCEIPLSGIV AVMKKCAKGV
960 970 980 990 1000
QSGEILQEYN MTQIPRFRDR ELSENVKKLL QQITTAVPGL KSGEIETYTW
1010 1020 1030 1040 1050
KELGSFCQNL DTSFDTDLLE KLEYNLNLPQ SFPARHCTRF DEHFSVLRDR
1060 1070 1080 1090 1100
IRIERKIESL EYELSSDALL LSEEYHNRLK VLEALNFVEQ KMVSLKGRIG
1110 1120 1130 1140 1150
CEIHHQELLI TELILDYKFH QRSPAELAAL LSTLTCQYNS GREMQFGGDT
1160 1170 1180 1190 1200
VFGEISESVK SVLTRLESVA SKHKSQISDL GCEIRFDLME VVYEWANGTP
1210 1220 1230 1240 1250
FYQIMEMTDC QEGLIVKCIQ RLDEVCKDVR NAGRIVGDPA LVEKMEEVSA
1260
SIRRDIVFAA SLYTTV
Length:1,266
Mass (Da):142,371
Last modified:October 31, 2006 - v3
Checksum:iD1002223D623FBF2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA92767.2.
PIRiT20487.
RefSeqiNP_502084.2. NM_069683.4.
UniGeneiCel.13189.

Genome annotation databases

EnsemblMetazoaiF01G4.3; F01G4.3; WBGene00008502.
GeneIDi178017.
KEGGicel:CELE_F01G4.3.
UCSCiF01G4.3. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ19103_CAEEL
AccessioniPrimary (citable) accession number: Q19103
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: October 31, 2006
Last modified: August 30, 2017
This is version 144 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported