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Protein

Cell division protein FtsZ

Gene

ftsZ2

Organism
Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei159GTPUniRule annotation1
Binding sitei162GTPUniRule annotation1
Binding sitei205GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi41 – 45GTPUniRule annotation5
Nucleotide bindingi128 – 130GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZ2Imported
Synonyms:ftsZUniRule annotation
Ordered Locus Names:HQ_1415AImported
OrganismiHaloquadratum walsbyi (strain DSM 16790 / HBSQ001)Imported
Taxonomic identifieri362976 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHaloferacalesHaloferacaceaeHaloquadratum
Proteomesi

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.UniRule annotation

Protein-protein interaction databases

STRINGi362976.HQ1415A

Structurei

3D structure databases

ProteinModelPortaliQ18KA8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 223TubulinInterPro annotationAdd BLAST191
Domaini225 – 342Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG02201 Archaea
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiIMNQGGV
OrthoDBiPOG093Z0942

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q18KA8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQDIVEEAMQ RDEEERDVAA EAGDDPEGFG SPRIVIVGAG GAGNNTVNRL
60 70 80 90 100
YNIGVDGADT VAINTDKQHL KMIEANTKIL VGKSLTQGLG AGGDPSMGER
110 120 130 140 150
ATEMAQGTIK DVLGEADLVF VTAGMGGGTG TGAAPVISKI AKEQGAIVVG
160 170 180 190 200
MVSTPFNVER ARTVKAEEGL EKLRNEADSI IVLDNNRLLD YVPNLPIGKA
210 220 230 240 250
FSVMDQIIAE TVKGISETIT QPSLINLDYA DMSTIMDQGG VAVMLVGETQ
260 270 280 290 300
DKNKTQEVVN DAMNHPLLDV DYRGASGGLV HITGGPDLTL KEAEGIADSI
310 320 330 340 350
TERLEASANV IWGARIQEEY KGKVRVMAIM TGVQSAQVLG PSTQKQADAS
360 370 380 390 400
RRSLEGSASE FNSTQGNTAN GSTSGSESTG WQSDGGRAPR EKQHGLDVIR
Length:400
Mass (Da):42,053
Last modified:July 25, 2006 - v1
Checksum:i20A5F79DC3758237
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180088 Genomic DNA Translation: CAJ51543.1
RefSeqiWP_011570698.1, NC_008212.1

Genome annotation databases

EnsemblBacteriaiCAJ51543; CAJ51543; HQ_1415A
GeneIDi4193999
KEGGihwa:HQ_1415A

Entry informationi

Entry nameiQ18KA8_HALWD
AccessioniPrimary (citable) accession number: Q18KA8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: March 28, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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