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Q18IL8 (Q18IL8_HALWD) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glyceraldehyde-3-phosphate dehydrogenase HAMAP-Rule MF_00559
Short name=GAPDH HAMAP-Rule MF_00559
EC=1.2.1.59 HAMAP-Rule MF_00559
Alternative name(s):
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase HAMAP-Rule MF_00559
Gene names
Name:gap3 EMBL CAJ52152.1
Synonyms:gap HAMAP-Rule MF_00559
Ordered Locus Names:HQ_2025A EMBL CAJ52152.1
OrganismHaloquadratum walsbyi (strain DSM 16790) [Complete proteome] [HAMAP] EMBL CAJ52152.1
Taxonomic identifier362976 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Haloquadratum ›

Protein attributes

Sequence length330 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H. HAMAP-Rule MF_00559 RuleBase RU003388 SAAS SAAS006436

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5. HAMAP-Rule MF_00559 RuleBase RU003388 SAAS SAAS006436

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00559 RuleBase RU003388 SAAS SAAS006436

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00559 RuleBase RU003388.

Sequence similarities

Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. HAMAP-Rule MF_00559 RuleBase RU000397

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding11 – 122NAD By similarity HAMAP-Rule MF_00559
Region138 – 1403Glyceraldehyde 3-phosphate binding By similarity HAMAP-Rule MF_00559
Region185 – 1862Glyceraldehyde 3-phosphate binding By similarity HAMAP-Rule MF_00559

Sites

Active site1391Nucleophile By similarity HAMAP-Rule MF_00559
Binding site1091NAD; via amide nitrogen By similarity HAMAP-Rule MF_00559

Sequences

Sequence LengthMass (Da)Tools
Q18IL8 [UniParc].

Last modified July 25, 2006. Version 1.
Checksum: AEE9C1D480BCB381

FASTA33036,247
        10         20         30         40         50         60 
MIHVGVNGYG TIGKRVADAV DMMPDMELTG VSKASPNHTA DAAADRGYDI YVPEERHDRW 

        70         80         90        100        110        120 
ADTEMTVTGD VHELIEISDI VADTTPPGMG AEYRPIYEEH DTPALFQGGE SADAVEASFT 

       130        140        150        160        170        180 
ARANYSEATN KDYVRIVSCN TTGLNRMFAP LHEEYGVERA SITLVRCRGE HAVTSADPMT 

       190        200        210        220        230        240 
IPSYHGPDAR EVIPDMGPIT TMGMKTPSVR HHFHGINVTL GAEPTAAEVR DLLASESRIH 

       250        260        270        280        290        300 
VIDDDLGIDS GWELQEFALD RGRDRMNLYE NQIFEDSITM DGTQLHLFQC IHRESDVVPE 

       310        320        330 
SIDAIRAMLA DADAVESIEL TNEVMGIGDI

« Hide

References

[1]"The genome of the square archaeon Haloquadratum walsbyi : life at the limits of water activity."
Bolhuis H.H., Palm P.P., Wende A.W., Falb M.M., Rampp M.M., Rodriguez-Valera F.F., Pfeiffer F.F., Oesterhelt D.D.
BMC Genomics 7:169-169(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 16790 EMBL CAJ52152.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM180088 Genomic DNA. Translation: CAJ52152.1.
RefSeqYP_657783.1. NC_008212.1.

3D structure databases

ProteinModelPortalQ18IL8.
ModBaseSearch...

Protein-protein interaction databases

STRING362976.HQ2025A.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ52152; CAJ52152; HQ_2025A.
GeneID4194011.
KEGGhwa:HQ2025A.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0057.
HOGENOMHOG000223361.
KOK00150.
ProtClustDBPRK04207.

Enzyme and pathway databases

BioCycHWAL362976:GJSR-1104-MONOMER.
UniPathwayUPA00109; UER00184.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
HAMAPMF_00559. G3P_dehdrog_arch.
InterProIPR020831. GlycerAld/Erythrose_P_DH.
IPR020830. GlycerAld_3-P_DH_AS.
IPR020829. GlycerAld_3-P_DH_cat.
IPR020828. GlycerAld_3-P_DH_NAD(P)-bd.
IPR006436. Glyceraldehyde-3-P_DH_2_arc.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF02800. Gp_dh_C. 1 hit.
PF00044. Gp_dh_N. 1 hit.
[Graphical view]
PIRSFPIRSF000149. GAP_DH. 1 hit.
SMARTSM00846. Gp_dh_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01546. GAPDH-II_archae. 1 hit.
PROSITEPS00071. GAPDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ18IL8_HALWD
AccessionPrimary (citable) accession number: Q18IL8
Entry history
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: May 1, 2013
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info