Q18GW9 (Q18GW9_HALWD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase RuleBase RU004370
EC=6.3.3.1 RuleBase RU004370

Gene names

Name:	purM EMBL CAJ52776.1
Ordered Locus Names:	HQ2665A

Organism

Haloquadratum walsbyi (strain DSM 16790) [Complete proteome] [HAMAP]

Taxonomic identifier

362976 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Haloquadratum

Protein attributes

Sequence length	342 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. RuleBase RU004370
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. RuleBase RU004371
Sequence similarities	Belongs to the AIR synthase family. RuleBase RU004370

Ontologies

Keywords
Molecular function	Ligase RuleBase RU004370 EMBL CAJ52776.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	phosphoribosylformylglycinamidine cyclo-ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q18GW9 [UniParc]. Last modified July 25, 2006. Version 1. Checksum: 6EDC312BC65480AF	FASTA	342	35,829
	10 20 30 40 50 60 MSNPPDDTAE RNTDIKTNAS EEDSDELTYA AAGVDIEASE AATAALIDAV GESAGDYAGL 70 80 90 100 110 120 IDIGDRYLAL ATDGVGTKLL VAAAMNEYST IGIDCIAMNV NDLVAAGVRP VAFVDYLAID 130 140 150 160 170 180 DPDENLTEQI GVGLDTGADI ADITLIGGET AVLPEVVDGF DLAGTCAGLT PKDGVFTETA 190 200 210 220 230 240 NPGDALVGFA SSGIHSNGLT LARTAITREY EYTAPCPFDE YETLGAALLE PTRIYTDLLD 250 260 270 280 290 300 PMHAHDVRTA AHITGGGLRN LERLGSHRYV IDDPFETPPI FEFVQSAGNV SDSEMYQTFN 310 320 330 340 MGTGFVCAMS PKNAEMLAEA TEGKIIGQVD TGEGVSIRGL EL

References

[1]

"The genome of the square archaeon Haloquadratum walsbyi: life at the limits of water activity." Bolhuis H., Palm P., Wende A., Falb M., Rampp M., Rodriguez-Valera F., Pfeiffer F., Oesterhelt D. BMC Genomics 7:169-169(2006) [PubMed: 16820047] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 16790.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM180088 Genomic DNA. Translation: CAJ52776.1.
RefSeq	YP_658382.1. NC_008212.1.
3D structure databases
ProteinModelPortal	Q18GW9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q18GW9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4194537.
GenomeReviews	Gene locus HQ2665A in contig AM180088_GR.
KEGG	hwa:HQ2665A.
NMPDR	fig|362976.6.peg.1670.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG04189.
HOGENOM	HBG531222.
OMA	GIDMIAM.
PhylomeDB	Q18GW9.
ProtClustDB	PRK05385.
Family and domain databases
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004733. PurM_cligase. IPR016188. PurM_N-like. [Graphical view]
KO	K01933.
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00878. PurM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q18GW9_HALWD

Accession

Primary (citable) accession number: Q18GW9

Entry history

Integrated into UniProtKB/TrEMBL:	July 25, 2006
Last sequence update:	July 25, 2006
Last modified:	January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)