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Q18FQ4 (G6PI_HALWD) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:HQ_3101A
OrganismHaloquadratum walsbyi (strain DSM 16790 / HBSQ001) [Complete proteome] [HAMAP]
Taxonomic identifier362976 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloquadratum

Protein attributes

Sequence length430 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 430430Probable glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000252605

Sites

Active site2711Proton donor By similarity
Active site2921 By similarity
Active site4031 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q18FQ4 [UniParc].

Last modified July 25, 2006. Version 1.
Checksum: 34AFADF81FE92D59

FASTA43045,583
        10         20         30         40         50         60 
MQVDLGTVFD ATPGVTQDGL ERLDERVATA HERIERGRRN NEPGYAALNL PETVDTTTIH 

        70         80         90        100        110        120 
DAVASFEDPT AILIVGIGGS ALGAATLVDA LGDDTAPSVY VLDNVDPASI SRILESIPLS 

       130        140        150        160        170        180 
ETVLNVVSRS GTTAETLSNF LVVREAMTKA GVDWTDRTIV TTGTDGNLRQ LAKSESLPAL 

       190        200        210        220        230        240 
SVPEGVPGRF SVLSTVGLVV AALKGIQISE LITGAADAAA ELSGSLFETP AYAYGATTYA 

       250        260        270        280        290        300 
LATRGARTNV MMPYAENLET FAEWFAQLWA ESLGKDNRGQ TPIRALGATD QHSQLQLYRA 

       310        320        330        340        350        360 
GPHNKVITLI RPRNRPSCTI PSTDLDGLSY LGGSDLGSLL DAEFEATEAS LVDADIPTIR 

       370        380        390        400        410        420 
VEINAIDAQS LGALLYEFEV ACICYGELAS VPTFTQPAVE WGKRAARGLL GDDKFMEAAA 

       430 
VADKPTLRVE 

« Hide

References

[1]"The genome of the square archaeon Haloquadratum walsbyi: life at the limits of water activity."
Bolhuis H., Palm P., Wende A., Falb M., Rampp M., Rodriguez-Valera F., Pfeiffer F., Oesterhelt D.
BMC Genomics 7:169-169(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 16790 / HBSQ001.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM180088 Genomic DNA. Translation: CAJ53201.1.
RefSeqYP_658798.1. NC_008212.1.

3D structure databases

ProteinModelPortalQ18FQ4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING362976.HQ3101A.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ53201; CAJ53201; HQ_3101A.
GeneID4194427.
KEGGhwa:HQ3101A.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000100402.
KOK01810.
OMARANDEHG.

Enzyme and pathway databases

BioCycHWAL362976:GJSR-2212-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_HALWD
AccessionPrimary (citable) accession number: Q18FQ4
Entry history
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: July 25, 2006
Last modified: June 11, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways