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Q18FC1 (SYR_HALWD) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:HQ_3239A
OrganismHaloquadratum walsbyi (strain DSM 16790 / HBSQ001) [Complete proteome] [HAMAP]
Taxonomic identifier362976 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloquadratum

Protein attributes

Sequence length596 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 596596Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000018039

Regions

Motif127 – 13711"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q18FC1 [UniParc].

Last modified July 25, 2006. Version 1.
Checksum: E71008C8B1183ED6

FASTA59666,431
        10         20         30         40         50         60 
MFRPFRSEVE HAVESALQTL ALPTDDLGVE TPPEDVPATL ASSVAFRLAR SAKDSPPRVA 

        70         80         90        100        110        120 
DDIAAAIDLE PDSQTYEYID HVDTRGPYIN FHVNDAYYMD TLTAAQDPGY GHLPNTGQSV 

       130        140        150        160        170        180 
VVEHTSANPT GPVHVGRGRN TIFGDAVARL LEYNGDTVDR HYYLNDAGRQ VGVFTWAYEK 

       190        200        210        220        230        240 
FDADSLPDPE RDRPDYDLVR YYRRGNEFLE NADADAVESA EDEIASIING LEAGNTETYE 

       250        260        270        280        290        300 
RVQTVVDQVI DGMQHSFDRL SAIFDEFIKE TRFIQNGDAD AVVERLKSAD CAVYEDDAWQ 

       310        320        330        340        350        360 
IDLSAYDIEK NLVFLRSDGT TLYTTRDLAH HEWKFDNYDA SVTILGEDHK LQAEQLDATL 

       370        380        390        400        410        420 
QILGNDTDQL RQPFYSWVNL PEGGMSTRKG TGVDLDDLLD EAIARAREEV HDRLGSRVRD 

       430        440        450        460        470        480 
DSLSSDDIDR IARQVGVGAV RYDIVSKQPT KGITFEWDRA LDFEAQSAPY IQYVHARCCG 

       490        500        510        520        530        540 
IETEVNSNTD LDIDALTSDS IPDITMLRTD AERALLQEIA RFPAVVESAA ADLEPHVIAT 

       550        560        570        580        590 
FARSFAEQFN TFYRECSVLN AESEIMTAAR VSLVRAARHT VANALDIVGV EAPQSM 

« Hide

References

[1]"The genome of the square archaeon Haloquadratum walsbyi: life at the limits of water activity."
Bolhuis H., Palm P., Wende A., Falb M., Rampp M., Rodriguez-Valera F., Pfeiffer F., Oesterhelt D.
BMC Genomics 7:169-169(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 16790 / HBSQ001.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM180088 Genomic DNA. Translation: CAJ53337.1.
RefSeqYP_658932.1. NC_008212.1.

3D structure databases

ProteinModelPortalQ18FC1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING362976.HQ3239A.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ53337; CAJ53337; HQ_3239A.
GeneID4193716.
KEGGhwa:HQ3239A.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247213.
KOK01887.
OMANPNGPLH.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycHWAL362976:GJSR-2357-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYR_HALWD
AccessionPrimary (citable) accession number: Q18FC1
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 25, 2006
Last modified: April 16, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries