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Protein

Translation initiation factor 6

Gene

eif6

Organism
Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.UniRule annotation

GO - Molecular functioni

  1. ribosome binding Source: InterPro
  2. translation initiation factor activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. mature ribosome assembly Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciHWAL362976:GJSR-2557-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor 6UniRule annotation
Short name:
aIF-6UniRule annotation
Gene namesi
Name:eif6UniRule annotation
Ordered Locus Names:HQ_3422A
OrganismiHaloquadratum walsbyi (strain DSM 16790 / HBSQ001)
Taxonomic identifieri362976 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloquadratum
ProteomesiUP000001975: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 226226Translation initiation factor 6PRO_0000259427Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi362976.HQ3422A.

Structurei

3D structure databases

ProteinModelPortaliQ18EU8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eIF-6 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1976.
HOGENOMiHOG000230604.
KOiK03264.
OMAiNDWCAFT.

Family and domain databases

HAMAPiMF_00032. eIF_6.
InterProiIPR002769. eIF6.
[Graphical view]
PANTHERiPTHR10784. PTHR10784. 1 hit.
PfamiPF01912. eIF-6. 1 hit.
[Graphical view]
PIRSFiPIRSF006413. IF-6. 1 hit.
SMARTiSM00654. eIF6. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00323. eIF-6. 1 hit.

Sequencei

Sequence statusi: Complete.

Q18EU8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRASFAGSP YVGVFARATD DVLLLRSDVD DDTADAMAAE LDIPAVATTI
60 70 80 90 100
GGSGTVGALA TGNENGILVT SNVTMREKEA IETTASVSVT ELPGRINAAG
110 120 130 140 150
NVILANDYGA YVHPDLSTEA VESIESALNV PVARGKLADV RTVGTAAVAT
160 170 180 190 200
NRGVLCHPKA REPELEAIED HLDVRADIGT VNYGAPLVGS GIVAGQTGYV
210 220
VGEDTTGPEL TRIEDTLGYL ESITSE
Length:226
Mass (Da):23,284
Last modified:July 25, 2006 - v1
Checksum:i8898BC95E5320E7B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180088 Genomic DNA. Translation: CAJ53519.1.
RefSeqiWP_011572616.1. NC_008212.1.
YP_659107.1. NC_008212.1.

Genome annotation databases

EnsemblBacteriaiCAJ53519; CAJ53519; HQ_3422A.
GeneIDi4194787.
KEGGihwa:HQ3422A.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180088 Genomic DNA. Translation: CAJ53519.1.
RefSeqiWP_011572616.1. NC_008212.1.
YP_659107.1. NC_008212.1.

3D structure databases

ProteinModelPortaliQ18EU8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi362976.HQ3422A.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ53519; CAJ53519; HQ_3422A.
GeneIDi4194787.
KEGGihwa:HQ3422A.

Phylogenomic databases

eggNOGiCOG1976.
HOGENOMiHOG000230604.
KOiK03264.
OMAiNDWCAFT.

Enzyme and pathway databases

BioCyciHWAL362976:GJSR-2557-MONOMER.

Family and domain databases

HAMAPiMF_00032. eIF_6.
InterProiIPR002769. eIF6.
[Graphical view]
PANTHERiPTHR10784. PTHR10784. 1 hit.
PfamiPF01912. eIF-6. 1 hit.
[Graphical view]
PIRSFiPIRSF006413. IF-6. 1 hit.
SMARTiSM00654. eIF6. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00323. eIF-6. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome of the square archaeon Haloquadratum walsbyi: life at the limits of water activity."
    Bolhuis H., Palm P., Wende A., Falb M., Rampp M., Rodriguez-Valera F., Pfeiffer F., Oesterhelt D.
    BMC Genomics 7:169-169(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 16790 / HBSQ001.

Entry informationi

Entry nameiIF6_HALWD
AccessioniPrimary (citable) accession number: Q18EU8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: July 25, 2006
Last modified: March 4, 2015
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.