Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Translational regulator CsrA

Gene

csrA

Organism
Peptoclostridium difficile (strain 630) (Clostridium difficile)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRepressor, RNA-binding
Biological processBacterial flagellum biogenesis, Translation regulation

Enzyme and pathway databases

BioCyciPDIF272563:G12WB-337-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Translational regulator CsrAUniRule annotation
Gene namesi
Name:csrAUniRule annotation
Ordered Locus Names:CD630_02340
OrganismiPeptoclostridium difficile (strain 630) (Clostridium difficile)
Taxonomic identifieri272563 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaeClostridioides
Proteomesi
  • UP000001978 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000233721 – 70Translational regulator CsrAAdd BLAST70

Proteomic databases

PRIDEiQ18CX3

Interactioni

Subunit structurei

Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.UniRule annotation

Protein-protein interaction databases

STRINGi272563.CD0234

Structurei

3D structure databases

ProteinModelPortaliQ18CX3
SMRiQ18CX3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CsrA/RsmA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105VM8 Bacteria
COG1551 LUCA
HOGENOMiHOG000020767
KOiK03563
OMAiIHRKEVY

Family and domain databases

Gene3Di3.30.70.1680, 1 hit
HAMAPiMF_00167 CsrA, 1 hit
InterProiView protein in InterPro
IPR003751 CsrA
IPR036107 CsrA_sf
PANTHERiPTHR34984 PTHR34984, 1 hit
PfamiView protein in Pfam
PF02599 CsrA, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD009007 CsrA, 1 hit
SUPFAMiSSF117130 SSF117130, 1 hit
TIGRFAMsiTIGR00202 csrA, 1 hit

Sequencei

Sequence statusi: Complete.

Q18CX3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVISRKKDE AVLIGDNIEV KVVGVDGNNI KLAISAPNNI SILRKEIYEK
60 70
VKNENIKATN KNIKILKSLK
Length:70
Mass (Da):7,800
Last modified:July 25, 2006 - v1
Checksum:i1D004D5736384260
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA Translation: CAJ67055.1
RefSeqiWP_003425267.1, NZ_CP010905.2
YP_001086702.1, NC_009089.1

Genome annotation databases

EnsemblBacteriaiCAJ67055; CAJ67055; CD630_02340
GeneIDi31351775
4916752
KEGGicdf:CD630_02340
pdc:CDIF630_00356
PATRICifig|272563.120.peg.250

Similar proteinsi

Entry informationi

Entry nameiCSRA_PEPD6
AccessioniPrimary (citable) accession number: Q18CX3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 25, 2006
Last modified: May 23, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health