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Protein

30S ribosomal protein S4

Gene

rpsD

Organism
Peptoclostridium difficile (strain 630) (Clostridium difficile)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.UniRule annotation
With S5 and S12 plays an important role in translational accuracy.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-156-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S4UniRule annotation
Gene namesi
Name:rpsDUniRule annotation
Ordered Locus Names:CD630_00970
OrganismiPeptoclostridium difficile (strain 630) (Clostridium difficile)
Taxonomic identifieri272563 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium
Proteomesi
  • UP000001978 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 20720730S ribosomal protein S4PRO_0000293260Add
BLAST

Proteomic databases

PRIDEiQ18CI6.

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.UniRule annotation

Protein-protein interaction databases

STRINGi272563.CD0097.

Structurei

3D structure databases

ProteinModelPortaliQ18CI6.
SMRiQ18CI6. Positions 2-207.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini98 – 16467S4 RNA-bindingUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ribosomal protein S4P family.UniRule annotation
Contains 1 S4 RNA-binding domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105G6W. Bacteria.
COG0522. LUCA.
HOGENOMiHOG000221003.
KOiK02986.
OMAiRTSDYGN.

Family and domain databases

Gene3Di1.10.1050.10. 1 hit.
3.10.290.10. 1 hit.
HAMAPiMF_01306_B. Ribosomal_S4_B. 1 hit.
InterProiIPR022801. Ribosomal_S4/S9.
IPR001912. Ribosomal_S4/S9_N.
IPR005709. Ribosomal_S4_bac-type.
IPR018079. Ribosomal_S4_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERiPTHR11831. PTHR11831. 1 hit.
PfamiPF00163. Ribosomal_S4. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTiSM01390. Ribosomal_S4. 1 hit.
SM00363. S4. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01017. rpsD_bact. 1 hit.
PROSITEiPS00632. RIBOSOMAL_S4. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q18CI6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARYTGASCR QCRREGMKLF LKGDRCYTDK CAIVKRNYAP GQHGQGRKKV
60 70 80 90 100
SNYGLQLREK QKVKRIYGVL ETQFRNLYER AENMPGKAGE NLLSLLERRL
110 120 130 140 150
DNVVYRMGLA SSRKEARQLV THGHFTLNGN KVDIPSLIVK VGDVIEVKEK
160 170 180 190 200
SRSSAKFKNL VEVNSRIAPK WLEANVEGMT AKVVGVPTRE DIDLEIAEHL

IIELYSK
Length:207
Mass (Da):23,566
Last modified:July 25, 2006 - v1
Checksum:iE24D5271B0C81468
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ66916.1.
RefSeqiWP_003421121.1. NZ_CP010905.1.
YP_001086565.1. NC_009089.1.

Genome annotation databases

EnsemblBacteriaiCAJ66916; CAJ66916; CD630_00970.
GeneIDi4913145.
KEGGicdf:CD630_00970.
pdc:CDIF630_00167.
PATRICi19438341. VBICloDif38397_0112.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ66916.1.
RefSeqiWP_003421121.1. NZ_CP010905.1.
YP_001086565.1. NC_009089.1.

3D structure databases

ProteinModelPortaliQ18CI6.
SMRiQ18CI6. Positions 2-207.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272563.CD0097.

Proteomic databases

PRIDEiQ18CI6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ66916; CAJ66916; CD630_00970.
GeneIDi4913145.
KEGGicdf:CD630_00970.
pdc:CDIF630_00167.
PATRICi19438341. VBICloDif38397_0112.

Phylogenomic databases

eggNOGiENOG4105G6W. Bacteria.
COG0522. LUCA.
HOGENOMiHOG000221003.
KOiK02986.
OMAiRTSDYGN.

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-156-MONOMER.

Family and domain databases

Gene3Di1.10.1050.10. 1 hit.
3.10.290.10. 1 hit.
HAMAPiMF_01306_B. Ribosomal_S4_B. 1 hit.
InterProiIPR022801. Ribosomal_S4/S9.
IPR001912. Ribosomal_S4/S9_N.
IPR005709. Ribosomal_S4_bac-type.
IPR018079. Ribosomal_S4_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERiPTHR11831. PTHR11831. 1 hit.
PfamiPF00163. Ribosomal_S4. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTiSM01390. Ribosomal_S4. 1 hit.
SM00363. S4. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01017. rpsD_bact. 1 hit.
PROSITEiPS00632. RIBOSOMAL_S4. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRS4_PEPD6
AccessioniPrimary (citable) accession number: Q18CI6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: July 25, 2006
Last modified: September 7, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.