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Protein
Submitted name:

Class III stress response-related ATPase, AAA+ superfamily

Gene

clpC

Organism
Peptoclostridium difficile (strain 630) (Clostridium difficile)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ChaperoneUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-79-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Class III stress response-related ATPase, AAA+ superfamilyImported
Gene namesi
Name:clpCImported
Ordered Locus Names:CD630_00260Imported
OrganismiPeptoclostridium difficile (strain 630) (Clostridium difficile)Imported
Taxonomic identifieri272563 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium
Proteomesi
  • UP000001978 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi272563.CD0026.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3FESX-ray1.82A/B/C/D2-143[»]
ProteinModelPortaliQ18CA9.
SMRiQ18CA9. Positions 166-349.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ18CA9.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini423 – 45836UVRInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ClpA/ClpB family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C2Z. Bacteria.
COG0542. LUCA.
HOGENOMiHOG000218210.
KOiK03696.
OMAiNYINTEH.
OrthoDBiEOG65F8SM.

Family and domain databases

Gene3Di1.10.1780.10. 1 hit.
3.40.50.300. 3 hits.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR019489. Clp_ATPase_C.
IPR004176. Clp_N.
IPR001270. ClpA/B.
IPR018368. ClpA/B_CS1.
IPR028299. ClpA/B_CS2.
IPR027417. P-loop_NTPase.
IPR001943. UVR_dom.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
PF07724. AAA_2. 1 hit.
PF02861. Clp_N. 2 hits.
PF10431. ClpB_D2-small. 1 hit.
PF02151. UVR. 1 hit.
[Graphical view]
PRINTSiPR00300. CLPPROTEASEA.
SMARTiSM00382. AAA. 2 hits.
SM01086. ClpB_D2-small. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF81923. SSF81923. 1 hit.
PROSITEiPS00870. CLPAB_1. 1 hit.
PS00871. CLPAB_2. 1 hit.
PS50151. UVR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q18CA9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNFNRFTQRA KKAIDLAFES AKSLGHNIVG SEHILLGLLR EEEGIAAKVL
60 70 80 90 100
SKVGFTEAYL EGKIVDMEGK GEEISEDIVL SPRSKQILEL SGMFANKLKT
110 120 130 140 150
NYIGTEHILL AIIQEGEGIA NKILNYAGVN DRTLAQLTID MMGISDKNQY
160 170 180 190 200
KAENSYTGNQ NQAESKVLDK YGRNLTLYAK QNKIDPVIGR EKEIQRVIQI
210 220 230 240 250
LSRRTKNNPV LIGDPGVGKT AIAEGLATNI ALGNVPETLK NKTLYSLEMG
260 270 280 290 300
SLLAGAKYRG EFEERIKEVV DEVVKNGNII LFIDEMHTII GAGSTGEGSI
310 320 330 340 350
DASNILKPAL ARGEIQVIGA TTIDEYRKHV EKDSALERRF QPVMVDEPTK
360 370 380 390 400
EDSIKILEGL RDKYEAHHKV KITDDAIKAA VELSTRYISD RYLPDKAIDL
410 420 430 440 450
IDEAASKVRL KENTPPSEIK KLELEIENID KEKEEAVRCQ DFEKAAKIRD
460 470 480 490 500
EQGLLKKQLE DVRERWNKSS KHSDLVDGEV IAEVVGLWTG IPVNKILEEE
510 520 530 540 550
ADRLLRLEEI LHNRVIGQEQ AVKSISKAIR RSRAGLKDPN RPIGSFLFLG
560 570 580 590 600
PTGVGKTELS KALAEVQFGD ENQIIRIDMS EYMEKHAVSR MIGSPPGYVG
610 620 630 640 650
HDEGGQLTEK VRRNPYSVIL FDEIEKAHPD VFNILLQILD DGRLTDSKGR
660 670 680 690 700
TVDFKNTIVI MTSNVGASTI GRQKTLGFSI AKGDEEEKSQ YEKMKENIMG
710 720 730 740 750
ELKQRFRPEF LNRIDDIIVF HSLNENHISK IVLLMAAKLQ ERLKEMDIKL
760 770 780 790 800
EMSDEAVKLI SKSGFDLEYG ARPLKRALQK ELEDELSEAI LKGNVKKGSN
810
VVAKVKDEKI VFETK
Length:815
Mass (Da):91,292
Last modified:July 25, 2006 - v1
Checksum:i2714CC51E80BB6FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ66840.1.
RefSeqiWP_003425582.1. NZ_CP010905.1.
YP_001086489.1. NC_009089.1.

Genome annotation databases

EnsemblBacteriaiCAJ66840; CAJ66840; CD630_00260.
GeneIDi4916495.
KEGGicdf:CD630_00260.
pdc:CDIF630_00088.
PATRICi19438187. VBICloDif38397_0035.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ66840.1.
RefSeqiWP_003425582.1. NZ_CP010905.1.
YP_001086489.1. NC_009089.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3FESX-ray1.82A/B/C/D2-143[»]
ProteinModelPortaliQ18CA9.
SMRiQ18CA9. Positions 166-349.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272563.CD0026.

Protocols and materials databases

DNASUi4916495.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ66840; CAJ66840; CD630_00260.
GeneIDi4916495.
KEGGicdf:CD630_00260.
pdc:CDIF630_00088.
PATRICi19438187. VBICloDif38397_0035.

Phylogenomic databases

eggNOGiENOG4105C2Z. Bacteria.
COG0542. LUCA.
HOGENOMiHOG000218210.
KOiK03696.
OMAiNYINTEH.
OrthoDBiEOG65F8SM.

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-79-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ18CA9.

Family and domain databases

Gene3Di1.10.1780.10. 1 hit.
3.40.50.300. 3 hits.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR019489. Clp_ATPase_C.
IPR004176. Clp_N.
IPR001270. ClpA/B.
IPR018368. ClpA/B_CS1.
IPR028299. ClpA/B_CS2.
IPR027417. P-loop_NTPase.
IPR001943. UVR_dom.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
PF07724. AAA_2. 1 hit.
PF02861. Clp_N. 2 hits.
PF10431. ClpB_D2-small. 1 hit.
PF02151. UVR. 1 hit.
[Graphical view]
PRINTSiPR00300. CLPPROTEASEA.
SMARTiSM00382. AAA. 2 hits.
SM01086. ClpB_D2-small. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF81923. SSF81923. 1 hit.
PROSITEiPS00870. CLPAB_1. 1 hit.
PS00871. CLPAB_2. 1 hit.
PS50151. UVR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 630Imported.
  2. "Crystal Structure of the ATP-dependent Clp Protease ClpC from Clostridium difficile."
    Kim Y., Tesar C., Li H., Cobb G., Joachimiak A.
    Submitted (DEC-2008) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.82 ANGSTROMS) OF 2-143.

Entry informationi

Entry nameiQ18CA9_PEPD6
AccessioniPrimary (citable) accession number: Q18CA9
Entry historyi
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: May 11, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.