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Protein

DNA replication and repair protein RecF

Gene

recF

Organism
Peptoclostridium difficile (strain 630) (Clostridium difficile)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi30 – 37ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA damage, DNA repair, DNA replication, SOS response
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPDIF272563:G12WB-4-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA replication and repair protein RecFUniRule annotation
Gene namesi
Name:recFUniRule annotation
Ordered Locus Names:CD630_00040
OrganismiPeptoclostridium difficile (strain 630) (Clostridium difficile)
Taxonomic identifieri272563 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaeClostridioides
Proteomesi
  • UP000001978 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000485121 – 371DNA replication and repair protein RecFAdd BLAST371

Interactioni

Protein-protein interaction databases

STRINGi272563.CD0004

Structurei

3D structure databases

ProteinModelPortaliQ18C86
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecF family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C3X Bacteria
COG1195 LUCA
HOGENOMiHOG000269559
KOiK03629
OMAiGQQKSFL

Family and domain databases

HAMAPiMF_00365 RecF, 1 hit
InterProiView protein in InterPro
IPR001238 DNA-binding_RecF
IPR018078 DNA-binding_RecF_CS
IPR027417 P-loop_NTPase
IPR003395 RecF/RecN/SMC_N
PANTHERiPTHR32182:SF0 PTHR32182:SF0, 1 hit
PfamiView protein in Pfam
PF02463 SMC_N, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
TIGRFAMsiTIGR00611 recf, 1 hit
PROSITEiView protein in PROSITE
PS00617 RECF_1, 1 hit
PS00618 RECF_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q18C86-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLKSLQLVN FRNYKKLHLE FNGKVNLLVG KNGQGKTNIV ESIYMLSFGK
60 70 80 90 100
SFRTNKDKEM VRFNSENLYI GGSFSKYNKY SLIELIIGKD KKGIRINKVP
110 120 130 140 150
LQKIQELLGN LNVVIFSPED LRLVKEGPKE RRAFIDKEIS QIIPKYYKYL
160 170 180 190 200
TNYNKTLSQR SRVLKNIHVD EALLDVYDDT LAKYGSYIYI LRRDFIKKIA
210 220 230 240 250
NISENMHMNL TNGVERLSIR YKNQINITDE DTIDTVYNKF LAKLSSNRPN
260 270 280 290 300
DIESKTTRYG IHKDDLNIFI NDLDARLFGS QGQQRTASIS LKLSEIELIK
310 320 330 340 350
NEVEEYPVLI LDDVFSELDE ARQKLLVNNL SNVQMFITSA EVSHKKIFDE
360 370
KNVTIFNIEN GDVISIENGG N
Length:371
Mass (Da):42,916
Last modified:July 25, 2006 - v1
Checksum:i2AB3C01BB1E11790
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA Translation: CAJ66818.1
RefSeqiWP_003429303.1, NZ_CP010905.2
YP_001086467.1, NC_009089.1

Genome annotation databases

EnsemblBacteriaiCAJ66818; CAJ66818; CD630_00040
GeneIDi31351435
4916180
KEGGicdf:CD630_00040
pdc:CDIF630_00004
PATRICifig|272563.120.peg.4

Similar proteinsi

Entry informationi

Entry nameiRECF_PEPD6
AccessioniPrimary (citable) accession number: Q18C86
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 25, 2006
Last modified: May 23, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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