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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Peptoclostridium difficile (strain 630) (Clostridium difficile)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei38NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciPDIF272563:G12WB-1448-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:CD630_13140
OrganismiPeptoclostridium difficile (strain 630) (Clostridium difficile)
Taxonomic identifieri272563 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaeClostridioides
Proteomesi
  • UP000001978 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000845711 – 301tRNA pseudouridine synthase BAdd BLAST301

Interactioni

Protein-protein interaction databases

STRINGi272563.CD1314

Structurei

3D structure databases

ProteinModelPortaliQ18BH7
SMRiQ18BH7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T Bacteria
COG0130 LUCA
HOGENOMiHOG000231225
KOiK03177
OMAiVDCSKGT

Family and domain databases

HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR014780 tRNA_psdUridine_synth_TruB
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

Q18BH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKIISILKP TGMTSHDVVS RVRKILNIKK VGHTGTLDPD ASGVLPICIG
60 70 80 90 100
KATKVCEVIL NKDKSYICEL TLGISTDTYD ASGEILKKVD DFKFSNEDIE
110 120 130 140 150
RAFDTQRGEI NQLPPIYSAL KVNGKRMCDL VRSGRQSEIT LKTRRVNIKD
160 170 180 190 200
IKILSIKGNK VMFYVECSKG TYVRSICHDI GEYLGCGAHM SFLNRTSSGK
210 220 230 240 250
FDLDNSITLE ELELFYENKT LDKYLYDIDY VLDSFNYVVL NPNAIKYYSN
260 270 280 290 300
GGSIDDKRFL KNNFDKDDEF VRVYSTDNFL GLGKLSKHNN TISVKSDKMF

I
Length:301
Mass (Da):34,091
Last modified:July 25, 2006 - v1
Checksum:i7C66655C842CD599
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA Translation: CAJ68171.1
RefSeqiWP_003428232.1, NZ_CP010905.2
YP_001087809.1, NC_009089.1

Genome annotation databases

EnsemblBacteriaiCAJ68171; CAJ68171; CD630_13140
GeneIDi31352901
4914473
KEGGicdf:CD630_13140
pdc:CDIF630_01470
PATRICifig|272563.120.peg.1374

Entry informationi

Entry nameiTRUB_PEPD6
AccessioniPrimary (citable) accession number: Q18BH7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 25, 2006
Last modified: March 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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