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Protein
Submitted name:

Pyrimidine-nucleoside phosphorylase

Gene

pdp

Organism
Peptoclostridium difficile (strain 630) (Clostridium difficile)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. phosphorylase activity Source: InterPro
  2. pyrimidine-nucleoside phosphorylase activity Source: UniProtKB-EC

GO - Biological processi

  1. pyrimidine nucleobase metabolic process Source: InterPro
  2. pyrimidine nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseSAAS annotationImported, Transferase

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-1390-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Pyrimidine-nucleoside phosphorylaseImported (EC:2.4.2.2Imported)
Gene namesi
Name:pdpImported
Ordered Locus Names:CD630_12250Imported
OrganismiPeptoclostridium difficile (strain 630) (Clostridium difficile)Imported
Taxonomic identifieri272563 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium
ProteomesiUP000001978 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi272563.CD1225.

Structurei

3D structure databases

ProteinModelPortaliQ18B84.
SMRiQ18B84. Positions 6-438.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000047312.
KOiK00756.
OMAiDWVVDAY.
OrthoDBiEOG61ZTGG.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR018090. Pyrmidine_PPas_bac/euk.
IPR017872. Pyrmidine_PPase_CS.
IPR000053. Thymidine/pyrmidine_PPase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000478. TP_PyNP. 1 hit.
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02644. Y_phosphoryl. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q18B84-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEISIMRMYD IIKKKRDNLE LSKKEINYFI ENYSKGDIPD YQASALLMSI
60 70 80 90 100
YLNKMNKQET VHLTEAMMNS GDMINLSEID GIKVDKHSTG GVGDKTTIAL
110 120 130 140 150
IPLVASCGAP VAKMSGRGLG HTGGTIDKLE SIPGFSTEME ISKFIDSVNK
160 170 180 190 200
SKIAVCGQSA KVAIADKKIY ALRDVTATVD NISLISSSVM SKKLASGADA
210 220 230 240 250
IVLDVKTGDG AFMKTLEESF ELAKSMVDIG TGMNRDTIGI VTDMDEPLGF
260 270 280 290 300
AVGNSLEVIE AIETLKGNGP KDLVELCEVL GAYMLVLSKV AHDFEDGVEK
310 320 330 340 350
IRESIKSGTA IQKLKEFIEN QGGNKDVVDD YSLFKKSKYK YPVKSTKSGY
360 370 380 390 400
ISKIKAEDVG VSAMILGAGR ETKDDILDLS AGIILEKKVG DYVNEGEVLA
410 420 430 440
YMYYNDEQKL SLAKGRFIDS YSIVDSKIEK NKLIYGIVTK EEIKKF
Length:446
Mass (Da):48,738
Last modified:July 25, 2006 - v1
Checksum:i286324FA5E6E1A2B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ68079.1.
RefSeqiYP_001087718.1. NC_009089.1.

Genome annotation databases

EnsemblBacteriaiCAJ68079; CAJ68079; CD630_12250.
GeneIDi4914867.
KEGGicdf:CD630_12250.
PATRICi19440793. VBICloDif38397_1284.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ68079.1.
RefSeqiYP_001087718.1. NC_009089.1.

3D structure databases

ProteinModelPortaliQ18B84.
SMRiQ18B84. Positions 6-438.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272563.CD1225.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ68079; CAJ68079; CD630_12250.
GeneIDi4914867.
KEGGicdf:CD630_12250.
PATRICi19440793. VBICloDif38397_1284.

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000047312.
KOiK00756.
OMAiDWVVDAY.
OrthoDBiEOG61ZTGG.

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-1390-MONOMER.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR018090. Pyrmidine_PPas_bac/euk.
IPR017872. Pyrmidine_PPase_CS.
IPR000053. Thymidine/pyrmidine_PPase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000478. TP_PyNP. 1 hit.
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02644. Y_phosphoryl. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 630Imported.

Entry informationi

Entry nameiQ18B84_PEPD6
AccessioniPrimary (citable) accession number: Q18B84
Entry historyi
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: April 1, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.