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Protein

Glycogen synthase

Gene

glgA

Organism
Peptoclostridium difficile (strain 630) (Clostridium difficile)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

  1. starch synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-1023-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:CD630_08840
OrganismiPeptoclostridium difficile (strain 630) (Clostridium difficile)
Taxonomic identifieri272563 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium
ProteomesiUP000001978 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 480480Glycogen synthasePRO_1000014347Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272563.CD0884.

Structurei

3D structure databases

ProteinModelPortaliQ18A79.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q18A79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVFYVTAEC WPFAKTGGLG DVSYALPKEL KKEGVDVRVI MPKYSTIPSY
60 70 80 90 100
LKDQLKEIAV FSVRVGWRNQ YCGLLEMELD GVKFYFIDNE FYFRREDERK
110 120 130 140 150
SIYGYGDDAE RYTFFTDAVL EAISRIDFYP DVIHINDWHT GMLPLILKER
160 170 180 190 200
YATLEGYKNI KTMYTIHNLQ YQGVFDKHVL YDILDLPQKY FDNGDIEYYG
210 220 230 240 250
SINFMKAGIN FADKIITVSP TYANEIQTSF YGEQLDGLLR KESGKLKGIL
260 270 280 290 300
NGIDYDLNDP AKDKDIFVHY DVDSINKKVE NKLRLQDILG LKKDSSIPLI
310 320 330 340 350
GIVSRLVSQK GFDLIAYMMP ELMREDLQIV VLGTGEHQYQ SMFNYYDSNF
360 370 380 390 400
SDKVSARITF NASLAQQIYA ASDMFLMPSL FEPCGIGQML AMRYGSLPIV
410 420 430 440 450
RETGGLRDTV TPYNKFTGEG NGFSFKNYNA HEMFFCLKNA IKVFKDKEKW
460 470 480
IKLVENAMKT DNSWKKSAKE YIETYRDICD
Length:480
Mass (Da):55,524
Last modified:July 25, 2006 - v1
Checksum:i29980A176CDC0960
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ67717.1.
RefSeqiYP_001087358.1. NC_009089.1.

Genome annotation databases

EnsemblBacteriaiCAJ67717; CAJ67717; CD630_08840.
GeneIDi4913419.
KEGGicdf:CD630_08840.
PATRICi19440061. VBICloDif38397_0923.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ67717.1.
RefSeqiYP_001087358.1. NC_009089.1.

3D structure databases

ProteinModelPortaliQ18A79.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272563.CD0884.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ67717; CAJ67717; CD630_08840.
GeneIDi4913419.
KEGGicdf:CD630_08840.
PATRICi19440061. VBICloDif38397_0923.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciCDIF272563:GJFE-1023-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 630.

Entry informationi

Entry nameiGLGA_PEPD6
AccessioniPrimary (citable) accession number: Q18A79
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 25, 2006
Last modified: January 7, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.