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Q189P4 (Q189P4_PEPD6) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phenylalanine--tRNA ligase alpha subunit HAMAP-Rule MF_00281

EC=6.1.1.20 HAMAP-Rule MF_00281
Alternative name(s):
Phenylalanyl-tRNA synthetase alpha subunit HAMAP-Rule MF_00281
Gene names
Name:pheS HAMAP-Rule MF_00281 EMBL CAJ67532.2
Ordered Locus Names:CD630_06990 EMBL CAJ67532.2
OrganismPeptoclostridium difficile (strain 630) (Clostridium difficile) [Complete proteome] [HAMAP] EMBL CAJ67532.2
Taxonomic identifier272563 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium

Protein attributes

Sequence length339 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe). HAMAP-Rule MF_00281 SAAS SAAS022911

Cofactor

Binds 2 magnesium ions per tetramer By similarity. HAMAP-Rule MF_00281 SAAS SAAS022911

Subunit structure

Tetramer of two alpha and two beta subunits By similarity. HAMAP-Rule MF_00281 SAAS SAAS022911

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00281 SAAS SAAS022911.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. HAMAP-Rule MF_00281

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2541Magnesium By similarity HAMAP-Rule MF_00281

Sequences

Sequence LengthMass (Da)Tools
Q189P4 [UniParc].

Last modified June 28, 2011. Version 2.
Checksum: 16B501BEA3EE3C32

FASTA33938,004
        10         20         30         40         50         60 
MQEKLLALRE AALAEIKEAQ SIESVESLRV KYLGKKGEIT AILKEMGKLS AEERPVVGKV 

        70         80         90        100        110        120 
ANEVRENIEL SINSKKEEIN AIEKERKLKE EVIDVTQPGK VLKVGKKHPI TQIIDEVTDI 

       130        140        150        160        170        180 
FIGMGFSIAE GPEVETVENN FDALNAPKDH PSRDMSDTFY INDGVLLRTQ TSPVQVRTMR 

       190        200        210        220        230        240 
SQELPIKVIA PGRCFRSDSP DATHSPMFHQ IEGLVVGKDV TMAEFKGTMD IFVEKLFGSD 

       250        260        270        280        290        300 
IKTKFRPHNF PFTEPSAEVD VTCFKCGGKG CPMCKYEGWI EILGSGMVHP NVLRNCGIDP 

       310        320        330 
EVYSGFAFGV GVERLAMLKY EIDDIRLLFE NDMRFLNQF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM180355 Genomic DNA. Translation: CAJ67532.2.
RefSeqYP_001087175.2. NC_009089.1.

3D structure databases

ProteinModelPortalQ189P4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272563.CD0699.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ67532; CAJ67532; CD630_06990.
GeneID4916807.
KEGGcdf:CD630_06990.
PATRIC19439681. VBICloDif38397_0734.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0016.
HOGENOMHOG000242675.
KOK01889.
OrthoDBEOG6WX4QN.

Family and domain databases

HAMAPMF_00281. Phe_tRNA_synth_alpha1.
InterProIPR006195. aa-tRNA-synth_II.
IPR004529. Phe-tRNA-synth_IIc_asu.
IPR004188. Phe-tRNA_ligase_II_N.
IPR022911. Phe_tRNA_ligase_alpha1_bac.
IPR002319. Phenylalanyl-tRNA_Synthase.
IPR010978. tRNA-bd_arm.
[Graphical view]
PfamPF02912. Phe_tRNA-synt_N. 1 hit.
PF01409. tRNA-synt_2d. 1 hit.
[Graphical view]
SUPFAMSSF46589. SSF46589. 1 hit.
TIGRFAMsTIGR00468. pheS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ189P4_PEPD6
AccessionPrimary (citable) accession number: Q189P4
Entry history
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: June 28, 2011
Last modified: June 11, 2014
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)