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Q189A6 (GLSA_PEPD6) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:CD630_05580
OrganismPeptoclostridium difficile (strain 630) (Clostridium difficile) [Complete proteome] [HAMAP]
Taxonomic identifier272563 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium

Protein attributes

Sequence length309 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 309309Glutaminase HAMAP-Rule MF_00313
PRO_1000048333

Sites

Binding site651Substrate By similarity
Binding site1171Substrate By similarity
Binding site1621Substrate By similarity
Binding site1691Substrate By similarity
Binding site1931Substrate By similarity
Binding site2451Substrate By similarity
Binding site2631Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q189A6 [UniParc].

Last modified July 25, 2006. Version 1.
Checksum: 23BA33CA6B2B95EF

FASTA30933,948
        10         20         30         40         50         60 
MNTLDETLLK EIISSNKKYT NYGQVASYIP ELKNARRNDL GICIIDSENN LYSAGNCSTK 

        70         80         90        100        110        120 
FTIQSISKPI VLAMALMDND WEDVFSNVGM EPSGDPFNSI MKLEINDTKK PCNPMINAGA 

       130        140        150        160        170        180 
IVTTSLINGS CLEEKEERML SFFRKLAKND NIGINYDVYK SEKMTGDRNR AMAYLLKSDG 

       190        200        210        220        230        240 
FIRGNVEDVL DLYFKQCSIE IDSVDLARIG INLANYGVDI ENGEHLMSEM VSRIVKTFMM 

       250        260        270        280        290        300 
TCGMYDASGE FAIKVGIPAK SGVGGGIMAS VPGRMGIGVY GPALDKKGNS VAGVKVLEEL 


SNKLKLNIF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM180355 Genomic DNA. Translation: CAJ67391.1.
RefSeqYP_001087034.1. NC_009089.1.

3D structure databases

ProteinModelPortalQ189A6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272563.CD0558.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ67391; CAJ67391; CD630_05580.
GeneID4916196.
KEGGcdf:CD630_05580.
PATRIC19439383. VBICloDif38397_0585.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMAQRARRIN.
OrthoDBEOG6N94BK.

Enzyme and pathway databases

BioCycCDIF272563:GJFE-691-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_PEPD6
AccessionPrimary (citable) accession number: Q189A6
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 25, 2006
Last modified: June 11, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families