Q18990 (Q18990_CAEEL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Protein PYR-1 EMBL CAA91059.2

Gene names

Name:	pyr-1 EMBL CAA91059.2 WormBase D2085.1
ORF Names:	CELE_D2085.1 EMBL CAA91059.2, D2085.1 WormBase D2085.1

Organism

Caenorhabditis elegans [Reference proteome] EMBL CAA91059.2

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	2198 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	'de novo' pyrimidine nucleobase biosynthetic process Inferred from electronic annotation. Source: InterPro carbamoyl phosphate biosynthetic process Inferred from electronic annotation. Source: InterPro glutamine catabolic process Inferred from electronic annotation. Source: InterPro pharynx development Inferred from mutant phenotype PubMed 16828468. Source: WormBase pyrimidine nucleobase biosynthetic process Inferred from mutant phenotype PubMed 16828468. Source: WormBase
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro amino acid binding Inferred from electronic annotation. Source: InterPro aspartate carbamoyltransferase activity Inferred from electronic annotation. Source: InterPro hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q18990 [UniParc]. Last modified February 5, 2008. Version 2. Checksum: 31CFC62E64D21B1E	FASTA	2,198	242,582
	10 20 30 40 50 60 MRATLHLEDG STFVGSIYGA TKSVVGEIVF QTGMVGYVES LTDPSYAKQL LTLTYPLIGN 70 80 90 100 110 120 YGVPSAEILD QFKLPAEFES DRIWPAALIV EKICVDGEHS HWQAVQSLSE WLRKADVPCL 130 140 150 160 170 180 SGIDVRQLVK KIRETGTMKA KLVIESDNAQ NFDYVDVNAE NLVDFVSRKE PVVYGSGDQT 190 200 210 220 230 240 ILAVDCGLKN NQIRCLAKRG FRVKVVPWNH PIDTESDYDG LFLSNGPGDP EICAPLVDRL 250 260 270 280 290 300 AKVIARGDKP IFGICLGHQI LSRAIGAKTY KLKYGNRGHN QPCTHYATGR CYITSQNHGY 310 320 330 340 350 360 AVDPDSLPAD WKALFTNEND KTNEGIVHSS KPFFSVQFHP EHTAGPTDCE FLFDVFADSV 370 380 390 400 410 420 RQAKSGTFMN VDQELTRLMT FTPIYHAKEQ RKVLVLGSGG LTIGQAGEFD YSGAQALKAL 430 440 450 460 470 480 REEGIRTVLI NPNIATVQTS KGFADFTYFL PITKEYVTDV IKKERPTGIL CTFGGQTALN 490 500 510 520 530 540 CAIDLYKDGI FEQYDVQVLG TQINTIMKTE DRDLFNQEIS AIGEKVAPSK AATTMEGAIE 550 560 570 580 590 600 AAEELGYPVL VRAAYALGGL GSGFADNREE LIAIAQQALA HSNQVLVDKS LKGWKEVEYE 610 620 630 640 650 660 VVRDAYDNCI TVCNMENVDP LGIHTGESVV VAPSQTLSDR EYNALRTCAI KVIRHLGIIG 670 680 690 700 710 720 ECNIQYALDP YSLTYYIIEV NARLSRSSAL ASKATGYPLA YVAAKLALGQ HLPVIRNSVT 730 740 750 760 770 780 GTTTACFEPS LDYCVVKIPR WDLGKFARVS TQIGSSMKSV GEVMGIGRCF EEALQKALRM 790 800 810 820 830 840 VSDHADGFSP YTFSRPTTAD DLSKPTDKRM FALARGMYYG DFDVEKAHEL TRIDRWFLFR 850 860 870 880 890 900 MQNIVDIYHR LEKTDVNTVS AELLLEAKQA GFSDRQIAKK IGSNEYTVRE ARFVKGITPC 910 920 930 940 950 960 VKQIDTVAGE WPAQTNYLYT TFNGIENDVS FNMKNAVMVL GSGVYRIGSS VEFDSSCVGC 970 980 990 1000 1010 1020 IRELKALGYS TITVNCNPET VSTDYDICDR LYFEEISFET VLDVYHLEKP KGVILAFGGQ 1030 1040 1050 1060 1070 1080 APNNIAMSLS RAQVKIFGTS PNDIDNAEDR FKFSRKLESL KISQPQWKKS ENMEDAKNFC 1090 1100 1110 1120 1130 1140 AQVGYPCLIR PSYVLSGAAM NVAHNAEDLE VFLKQAAVVA KEHPVVVSKF INEAKELDVD 1150 1160 1170 1180 1190 1200 AVALDGKLVV MAVSEHIENA GVHSGDATLV TPAQDMNKLT LDRIKDITFR IAEAFNVNGP 1210 1220 1230 1240 1250 1260 FNMQLIAKNN ELKVIECNLR VSRSFPFVSK TLDYDFVALA TRAMMASDSP AIRATIKPTA 1270 1280 1290 1300 1310 1320 TLLKGKGRVG VKVPQFSFSR LAGADVMLGV EMASTGEVAC FGTSRCDAYL KALLSTGFVV 1330 1340 1350 1360 1370 1380 PKQNIFISIG GYHAKAEMLK SVEALLKLGY ELYGSKGTAD YFQSNKINVK PVDWPFEEGS 1390 1400 1410 1420 1430 1440 SDEKTASGTR SVVEFLENKE FHLVINLPIR GSGAYRVSAF RTHGYKTRRM AIDNGIPLIT 1450 1460 1470 1480 1490 1500 DIKCAKTFIQ ALEMVGKRPT MNSLVDCVTS KSLKRLPGMV DIHVHVREPG ATHKEDWATC 1510 1520 1530 1540 1550 1560 SKAALAGGVT TILAMPNTSP VLVDTDSFYQ TEQLASAKSV VDYALYIGAT PNNSKFAAEF 1570 1580 1590 1600 1610 1620 ADKAAGLKMY LNETFSTLKM DNISDWAKHL SAFPANRPIV CHAEKQTLAA ILCMAQMANR 1630 1640 1650 1660 1670 1680 AVHIAHVATA DEINLVKEAK QRGWNVTCEV CPHHLFLIEE DLPDGIREVR PRLVKPEDRQ 1690 1700 1710 1720 1730 1740 ALWDNMEYID CFATDHAPHT WAEKTGKDGK IPPGFPGVEY MLPLLLTAVH DGKLTMKELT 1750 1760 1770 1780 1790 1800 DRMSTNPRRI FNLPPQDDTY IEVDLNEEWT IPENGGQSKA GWTPFAGRKV FGKVHNVIIR 1810 1820 1830 1840 1850 1860 GEEAVIDGRI VAIPGFGKNV RLYPHSGTAH RGDSDFDQIL EPIPQQMIES SSDEQSPLHT 1870 1880 1890 1900 1910 1920 PPRAHTPIAF PGELLAKNCI SVKHLDKGQI NRIFELADRY KHDVEKGHPL THILNGKVLV 1930 1940 1950 1960 1970 1980 NLFYEVSTRT SCSFSAAMQR LGGSVISVDS QSSSVQKGET LEDTVQVLGS YGDILVLRSN 1990 2000 2010 2020 2030 2040 ENGAADRAAR VCDQPVINGG DGTGEHPTQA LLDVYTIRQE MGTVNGLTIA LVGDLKNGRT 2050 2060 2070 2080 2090 2100 VHSLAKLLCL YKDITLHYVA PSTELEMPQE VLDYVSSKSN FVQKKFTSLA EGINHVDVVY 2110 2120 2130 2140 2150 2160 VTRIQKERFS SPDEYNKVKG SYVINAKLLN EAARDVEEPS SLLVPARSLP IVMHPLPRVD 2170 2180 2190 EIAVELDHDE RAAYFRQAKN GVFVRMSILS LLLGRGHL

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." Caenorhabditis elegans Sequencing Consortium Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2 EMBL CAA91059.2.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z54284 Genomic DNA. Translation: CAA91059.2.
RefSeq	NP_495838.2. NM_063437.4.
UniGene	Cel.33265.
3D structure databases
ProteinModelPortal	Q18990.
ModBase	Search...
Protein-protein interaction databases
STRING	6239.D2085.1.
Proteomic databases
PaxDb	Q18990.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	D2085.1; D2085.1; D2085.1.
GeneID	174385.
KEGG	cel:CELE_D2085.1.
UCSC	D2085.1. c. elegans.
Organism-specific databases
CTD	174385.
WormBase	D2085.1; CE41886; WBGene00004259; pyr-1.
Phylogenomic databases
eggNOG	COG0458.
GeneTree	ENSGT00390000015604.
HOGENOM	HOG000234584.
InParanoid	Q18990.
KO	K11540.
OMA	QRPVHIC.
Family and domain databases
Gene3D	1.10.1030.10. 1 hit. 3.30.1490.20. 1 hit. 3.30.470.20. 2 hits. 3.40.50.1370. 2 hits. 3.40.50.1380. 1 hit. 3.40.50.20. 2 hits. 3.50.30.20. 1 hit.
HAMAP	MF_00001. Asp_carb_tr. MF_01209. CPSase_S_chain.
InterPro	IPR006680. Amidohydro_1. IPR006132. Asp/Orn_carbamoyltranf_P-bd. IPR006130. Asp/Orn_carbamoylTrfase. IPR002082. Asp_carbamoyltransf. IPR006131. Asp_carbamoyltransf_Asp/Orn-bd. IPR011761. ATP-grasp. IPR013815. ATP_grasp_subdomain_1. IPR013816. ATP_grasp_subdomain_2. IPR006275. CarbamoylP_synth_lsu. IPR005481. CarbamoylP_synth_lsu_N. IPR005480. CarbamoylP_synth_lsu_oligo. IPR006274. CarbamoylP_synth_ssu. IPR002474. CarbamoylP_synth_ssu_N. IPR005479. CbamoylP_synth_lsu-like_ATP-bd. IPR005483. CbamoylP_synth_lsu_CPSase_dom. IPR002195. Dihydroorotase_CS. IPR017926. GATASE. IPR011059. Metal-dep_hydrolase_composite. IPR011607. MGS-like_dom. IPR016185. PreATP-grasp_dom. [Graphical view]
Pfam	PF01979. Amidohydro_1. 1 hit. PF00289. CPSase_L_chain. 2 hits. PF02786. CPSase_L_D2. 2 hits. PF02787. CPSase_L_D3. 1 hit. PF00988. CPSase_sm_chain. 1 hit. PF00117. GATase. 1 hit. PF02142. MGS. 1 hit. PF00185. OTCace. 1 hit. PF02729. OTCace_N. 1 hit. [Graphical view]
PRINTS	PR00100. AOTCASE. PR00101. ATCASE. PR00098. CPSASE.
SMART	SM01096. CPSase_L_D3. 1 hit. SM01097. CPSase_sm_chain. 1 hit. SM00851. MGS. 1 hit. [Graphical view]
SUPFAM	SSF53671. Asp/Orn_carbamoyltranf. 1 hit. SSF48108. CarbamoylP_synth_lsu_oligo. 1 hit. SSF52021. CP_synthsmall. 1 hit. SSF51338. Metalo_hydrolase. 1 hit. SSF52335. MGS-like_dom. 1 hit. SSF52440. PreATP-grasp-like. 2 hits.
TIGRFAMs	TIGR00670. asp_carb_tr. 1 hit. TIGR01369. CPSaseII_lrg. 1 hit. TIGR01368. CPSaseIIsmall. 1 hit.
PROSITE	PS50975. ATP_GRASP. 2 hits. PS00097. CARBAMOYLTRANSFERASE. 1 hit. PS00866. CPSASE_1. 2 hits. PS00867. CPSASE_2. 2 hits. PS00482. DIHYDROOROTASE_1. 1 hit. PS00483. DIHYDROOROTASE_2. 1 hit. PS51273. GATASE_TYPE_1. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	883806.

Entry information

Entry name

Q18990_CAEEL

Accession

Primary (citable) accession number: Q18990

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	February 5, 2008
Last modified:	May 29, 2013
This is version 107 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)