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Protein
Submitted name:

Putative RNA methylase

Gene

CD630_17800

Organism
Peptoclostridium difficile (strain 630) (Clostridium difficile)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei261 – 2611GTPCombined sources

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi174 – 1763GTPCombined sources
Nucleotide bindingi199 – 2057GTPCombined sources
Nucleotide bindingi288 – 2903GTPCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseSAAS annotationImported, Transferase

Keywords - Ligandi

GTP-bindingCombined sources, Nucleotide-binding

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-1968-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative RNA methylaseImported
Gene namesi
Ordered Locus Names:CD630_17800Imported
OrganismiPeptoclostridium difficile (strain 630) (Clostridium difficile)Imported
Taxonomic identifieri272563 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium
Proteomesi
  • UP000001978 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi272563.CD1780.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3LDUX-ray1.70A1-382[»]
ProteinModelPortaliQ186Y7.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ186Y7.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini45 – 157113THUMPInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the methyltransferase superfamily.SAAS annotation
Contains THUMP domain.SAAS annotation

Phylogenomic databases

eggNOGiENOG4105C4H. Bacteria.
COG0116. LUCA.
HOGENOMiHOG000040914.
KOiK07444.
OMAiGFMYKAN.

Family and domain databases

Gene3Di3.40.50.150. 2 hits.
InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR000241. RNA_methylase_dom.
IPR029063. SAM-dependent_MTases.
IPR004114. THUMP_dom.
[Graphical view]
PfamiPF02926. THUMP. 1 hit.
PF01170. UPF0020. 1 hit.
[Graphical view]
SMARTiSM00981. THUMP. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 2 hits.
PROSITEiPS00092. N6_MTASE. 1 hit.
PS51165. THUMP. 1 hit.
PS01261. UPF0020. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q186Y7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNYTLISPC FFGMEKMLAR EITNLGYEII KTEDGRITYK TDEFGIAKSN
60 70 80 90 100
MWLRCAERVH LKIAEFEAKS FDELFENTKR INWSRYIPYG AQFPISKASS
110 120 130 140 150
IKSKLYSTPD VQAIVKKAIV ESLKKSYLED GLLKEDKEKY PIFVFIHKDK
160 170 180 190 200
VTISIDTTGD ALHKRGYREK ANKAPIRETL AAGLIYLTPW KAGRVLVDPM
210 220 230 240 250
CGSGTILIEA AMIGINMAPG LNREFISEKW RTLDKKIWWD VRKDAFNKID
260 270 280 290 300
NESKFKIYGY DIDEESIDIA RENAEIAGVD EYIEFNVGDA TQFKSEDEFG
310 320 330 340 350
FIITNPPYGE RLEDKDSVKQ LYKELGYAFR KLKNWSYYLI TSYEDFEYEF
360 370 380
GQKADKKRKL YNGMLKTNFF QYPGPKPPRN NK
Length:382
Mass (Da):44,398
Last modified:July 25, 2006 - v1
Checksum:i6F6CE94A3E6BB0A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ68650.1.
RefSeqiWP_003423769.1. NZ_CP010905.1.
YP_001088286.1. NC_009089.1.

Genome annotation databases

EnsemblBacteriaiCAJ68650; CAJ68650; CD630_17800.
GeneIDi4914978.
KEGGicdf:CD630_17800.
pdc:CDIF630_01978.
PATRICi19441963. VBICloDif38397_1868.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ68650.1.
RefSeqiWP_003423769.1. NZ_CP010905.1.
YP_001088286.1. NC_009089.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3LDUX-ray1.70A1-382[»]
ProteinModelPortaliQ186Y7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272563.CD1780.

Protocols and materials databases

DNASUi4914978.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ68650; CAJ68650; CD630_17800.
GeneIDi4914978.
KEGGicdf:CD630_17800.
pdc:CDIF630_01978.
PATRICi19441963. VBICloDif38397_1868.

Phylogenomic databases

eggNOGiENOG4105C4H. Bacteria.
COG0116. LUCA.
HOGENOMiHOG000040914.
KOiK07444.
OMAiGFMYKAN.

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-1968-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ186Y7.

Family and domain databases

Gene3Di3.40.50.150. 2 hits.
InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR000241. RNA_methylase_dom.
IPR029063. SAM-dependent_MTases.
IPR004114. THUMP_dom.
[Graphical view]
PfamiPF02926. THUMP. 1 hit.
PF01170. UPF0020. 1 hit.
[Graphical view]
SMARTiSM00981. THUMP. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 2 hits.
PROSITEiPS00092. N6_MTASE. 1 hit.
PS51165. THUMP. 1 hit.
PS01261. UPF0020. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ186Y7_PEPD6
AccessioniPrimary (citable) accession number: Q186Y7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: September 7, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.