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Protein
Submitted name:

Uncharacterized protein

Gene

unc-130

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • RNA polymerase II regulatory region sequence-specific DNA binding Source: WormBase
  • RNA polymerase II transcription corepressor activity Source: WormBase
  • RNA polymerase II transcription factor activity, sequence-specific DNA binding Source: GO_Central
  • transcription factor activity, sequence-specific DNA binding Source: WormBase

GO - Biological processi

  • axon extension involved in axon guidance Source: WormBase
  • embryo development ending in birth or egg hatching Source: WormBase
  • maintenance of protein location Source: WormBase
  • negative regulation of transcription from RNA polymerase II promoter Source: WormBase
  • nematode male tail tip morphogenesis Source: WormBase
  • nervous system development Source: WormBase
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

TranscriptionSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:unc-130Imported
ORF Names:C47G2.2Imported, CELE_C47G2.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiC47G2.2; CE02166; WBGene00006853; unc-130.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

  • nucleus Source: WormBase
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiQ18694.

Expressioni

Gene expression databases

BgeeiWBGene00006853.

Interactioni

Protein-protein interaction databases

IntActiQ18694. 24 interactors.
STRINGi6239.C47G2.2.

Structurei

3D structure databases

ProteinModelPortaliQ18694.
SMRiQ18694.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini127 – 221Fork-head DNA-bindingInterPro annotationAdd BLAST95

Phylogenomic databases

eggNOGiKOG2294. Eukaryota.
COG5025. LUCA.
GeneTreeiENSGT00760000118904.
HOGENOMiHOG000016824.
InParanoidiQ18694.
KOiK09397.
OMAiMLFSMES.
OrthoDBiEOG091G0HW9.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. Fork_head_dom.
IPR030456. TF_fork_head_CS_2.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00250. Forkhead. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q18694-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLFSMESILS STKPKLEPPP KLEPEVTINE QVVDLPRSNT RLSEPSTSAS
60 70 80 90 100
VLEHDLKFGE SRKRSRSLGD EPTEDEDGVP VRKANKRNHS TSSAADSSSD
110 120 130 140 150
DAKDDDDDDD STSRKSMSGH RKSSHAKPPY SYIALIAMSI LNSPEKKLTL
160 170 180 190 200
SEICEFIINK FEYYKEKFPA WQNSIRHNLS LNDCFVKVAR GPGNPGKGNY
210 220 230 240 250
WALDPNCEDM FDNGSFLRRR KRYKKNSDTY HEMMSHHPMP FPPFLPQGMP
260 270 280 290 300
FPPRMMHPMA NIPMLGHPMN PRAVPNMPAF FIPQNIDSQK LLSMMASRIM
310 320 330
PMDAPVSSGQ KRTSSSSSPN ENGSSAVSDK LSA
Length:333
Mass (Da):37,292
Last modified:November 1, 1996 - v1
Checksum:i79FEE50B4D665699
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CAA88935.1.
PIRiT20033.
RefSeqiNP_496411.1. NM_064010.3.
UniGeneiCel.22561.

Genome annotation databases

EnsemblMetazoaiC47G2.2; C47G2.2; WBGene00006853.
GeneIDi174721.
KEGGicel:CELE_C47G2.2.
UCSCiC47G2.2. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CAA88935.1.
PIRiT20033.
RefSeqiNP_496411.1. NM_064010.3.
UniGeneiCel.22561.

3D structure databases

ProteinModelPortaliQ18694.
SMRiQ18694.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ18694. 24 interactors.
STRINGi6239.C47G2.2.

Proteomic databases

PaxDbiQ18694.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC47G2.2; C47G2.2; WBGene00006853.
GeneIDi174721.
KEGGicel:CELE_C47G2.2.
UCSCiC47G2.2. c. elegans.

Organism-specific databases

CTDi174721.
WormBaseiC47G2.2; CE02166; WBGene00006853; unc-130.

Phylogenomic databases

eggNOGiKOG2294. Eukaryota.
COG5025. LUCA.
GeneTreeiENSGT00760000118904.
HOGENOMiHOG000016824.
InParanoidiQ18694.
KOiK09397.
OMAiMLFSMES.
OrthoDBiEOG091G0HW9.

Gene expression databases

BgeeiWBGene00006853.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. Fork_head_dom.
IPR030456. TF_fork_head_CS_2.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00250. Forkhead. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ18694_CAEEL
AccessioniPrimary (citable) accession number: Q18694
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 30, 2016
This is version 135 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.