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Protein
Submitted name:

Uncharacterized protein

Gene

unc-130

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi127 – 221Fork-headPROSITE-ProRule annotationAdd BLAST95

GO - Molecular functioni

  • DNA binding transcription factor activity Source: WormBase
  • RNA polymerase II regulatory region sequence-specific DNA binding Source: WormBase
  • RNA polymerase II transcription corepressor activity Source: WormBase
  • RNA polymerase II transcription factor activity, sequence-specific DNA binding Source: GO_Central

GO - Biological processi

  • axon extension involved in axon guidance Source: WormBase
  • embryo development ending in birth or egg hatching Source: WormBase
  • maintenance of protein location Source: WormBase
  • negative regulation of transcription by RNA polymerase II Source: WormBase
  • nematode male tail tip morphogenesis Source: WormBase
  • nervous system development Source: WormBase
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscriptionSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:unc-130Imported
ORF Names:C47G2.2Imported, CELE_C47G2.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiC47G2.2 ; CE02166 ; WBGene00006853 ; unc-130

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

EPDiQ18694
PaxDbiQ18694

Expressioni

Gene expression databases

BgeeiWBGene00006853

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

IntActiQ18694 24 interactors.
STRINGi6239.C47G2.2

Structurei

3D structure databases

ProteinModelPortaliQ18694
SMRiQ18694
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini127 – 221Fork-headInterPro annotationAdd BLAST95

Phylogenomic databases

eggNOGiKOG2294 Eukaryota
COG5025 LUCA
GeneTreeiENSGT00760000118904
HOGENOMiHOG000016824
InParanoidiQ18694
KOiK09397
OMAiMLFSMES
OrthoDBiEOG091G0HW9

Family and domain databases

CDDicd00059 FH, 1 hit
Gene3Di1.10.10.101 hit
InterProiView protein in InterPro
IPR001766 Fork_head_dom
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00250 Forkhead, 1 hit
PRINTSiPR00053 FORKHEAD
SMARTiView protein in SMART
SM00339 FH, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00658 FORK_HEAD_2, 1 hit
PS50039 FORK_HEAD_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q18694-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLFSMESILS STKPKLEPPP KLEPEVTINE QVVDLPRSNT RLSEPSTSAS
60 70 80 90 100
VLEHDLKFGE SRKRSRSLGD EPTEDEDGVP VRKANKRNHS TSSAADSSSD
110 120 130 140 150
DAKDDDDDDD STSRKSMSGH RKSSHAKPPY SYIALIAMSI LNSPEKKLTL
160 170 180 190 200
SEICEFIINK FEYYKEKFPA WQNSIRHNLS LNDCFVKVAR GPGNPGKGNY
210 220 230 240 250
WALDPNCEDM FDNGSFLRRR KRYKKNSDTY HEMMSHHPMP FPPFLPQGMP
260 270 280 290 300
FPPRMMHPMA NIPMLGHPMN PRAVPNMPAF FIPQNIDSQK LLSMMASRIM
310 320 330
PMDAPVSSGQ KRTSSSSSPN ENGSSAVSDK LSA
Length:333
Mass (Da):37,292
Last modified:November 1, 1996 - v1
Checksum:i79FEE50B4D665699
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA Translation: CAA88935.1
PIRiT20033
RefSeqiNP_496411.1, NM_064010.3
UniGeneiCel.22561

Genome annotation databases

EnsemblMetazoaiC47G2.2; C47G2.2; WBGene00006853
GeneIDi174721
KEGGicel:CELE_C47G2.2
UCSCiC47G2.2 c. elegans

Similar proteinsi

Entry informationi

Entry nameiQ18694_CAEEL
AccessioniPrimary (citable) accession number: Q18694
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 145 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported