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Protein
Submitted name:

Uncharacterized protein

Gene

unc-130

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi127 – 221Fork-headPROSITE-ProRule annotationAdd BLAST95

GO - Molecular functioni

  • RNA polymerase II regulatory region sequence-specific DNA binding Source: WormBase
  • RNA polymerase II transcription corepressor activity Source: WormBase
  • RNA polymerase II transcription factor activity, sequence-specific DNA binding Source: GO_Central
  • transcription factor activity, sequence-specific DNA binding Source: WormBase

GO - Biological processi

  • axon extension involved in axon guidance Source: WormBase
  • embryo development ending in birth or egg hatching Source: WormBase
  • maintenance of protein location Source: WormBase
  • negative regulation of transcription from RNA polymerase II promoter Source: WormBase
  • nematode male tail tip morphogenesis Source: WormBase
  • nervous system development Source: WormBase
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscriptionSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:unc-130Imported
ORF Names:C47G2.2Imported, CELE_C47G2.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiC47G2.2; CE02166; WBGene00006853; unc-130.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

  • nucleus Source: WormBase

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

EPDiQ18694.
PaxDbiQ18694.

Expressioni

Gene expression databases

BgeeiWBGene00006853.

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

IntActiQ18694. 24 interactors.
STRINGi6239.C47G2.2.

Structurei

3D structure databases

ProteinModelPortaliQ18694.
SMRiQ18694.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini127 – 221Fork-head DNA-bindingInterPro annotationAdd BLAST95

Phylogenomic databases

eggNOGiKOG2294. Eukaryota.
COG5025. LUCA.
GeneTreeiENSGT00760000118904.
HOGENOMiHOG000016824.
InParanoidiQ18694.
KOiK09397.
OMAiMLFSMES.
OrthoDBiEOG091G0HW9.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR001766. Fork_head_dom.
IPR030456. TF_fork_head_CS_2.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00250. Forkhead. 1 hit.
PRINTSiPR00053. FORKHEAD.
SMARTiView protein in SMART
SM00339. FH. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q18694-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLFSMESILS STKPKLEPPP KLEPEVTINE QVVDLPRSNT RLSEPSTSAS
60 70 80 90 100
VLEHDLKFGE SRKRSRSLGD EPTEDEDGVP VRKANKRNHS TSSAADSSSD
110 120 130 140 150
DAKDDDDDDD STSRKSMSGH RKSSHAKPPY SYIALIAMSI LNSPEKKLTL
160 170 180 190 200
SEICEFIINK FEYYKEKFPA WQNSIRHNLS LNDCFVKVAR GPGNPGKGNY
210 220 230 240 250
WALDPNCEDM FDNGSFLRRR KRYKKNSDTY HEMMSHHPMP FPPFLPQGMP
260 270 280 290 300
FPPRMMHPMA NIPMLGHPMN PRAVPNMPAF FIPQNIDSQK LLSMMASRIM
310 320 330
PMDAPVSSGQ KRTSSSSSPN ENGSSAVSDK LSA
Length:333
Mass (Da):37,292
Last modified:November 1, 1996 - v1
Checksum:i79FEE50B4D665699
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CAA88935.1.
PIRiT20033.
RefSeqiNP_496411.1. NM_064010.3.
UniGeneiCel.22561.

Genome annotation databases

EnsemblMetazoaiC47G2.2; C47G2.2; WBGene00006853.
GeneIDi174721.
KEGGicel:CELE_C47G2.2.
UCSCiC47G2.2. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ18694_CAEEL
AccessioniPrimary (citable) accession number: Q18694
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: August 30, 2017
This is version 141 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported