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Protein
Submitted name:

Uncharacterized protein

Gene

C47E12.2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransportUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-CEL-422356. Regulation of insulin secretion.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
ORF Names:C47E12.2Imported, CELE_C47E12.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiC47E12.2; CE05446; WBGene00008147.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei184 – 203HelicalSequence analysisAdd BLAST20
Transmembranei223 – 242HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiQ18683.
PaxDbiQ18683.
PeptideAtlasiQ18683.

Expressioni

Gene expression databases

BgeeiWBGene00008147.

Interactioni

Protein-protein interaction databases

IntActiQ18683. 1 interactor.
STRINGi6239.C47E12.2.2.

Structurei

3D structure databases

ProteinModelPortaliQ18683.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati19 – 111SolcarPROSITE-ProRule annotationAdd BLAST93
Repeati124 – 213SolcarPROSITE-ProRule annotationAdd BLAST90
Repeati221 – 305SolcarPROSITE-ProRule annotationAdd BLAST85

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0749. Eukaryota.
ENOG410XNW0. LUCA.
GeneTreeiENSGT00390000011543.
HOGENOMiHOG000165727.
InParanoidiQ18683.
KOiK05863.
OMAiADINHHT.
OrthoDBiEOG091G0ULB.
PhylomeDBiQ18683.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR002113. Aden_trnslctor.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
PRINTSiPR00927. ADPTRNSLCASE.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

Q18683-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTSASLSPA ALQKRSDAQK FAIDLLIGGV SASVSKTVVA PIERVKILLQ
60 70 80 90 100
VQYSHKDIPA DKRYNGIIDA FVRVPKEQGF VSFWRGNMTN VIRYFPTQAF
110 120 130 140 150
NFAFNDLYKS ILLKNMKREN NVLSYSVRTL VSGGLAGCSS LCIVYPLDFI
160 170 180 190 200
RTRLSADINH HTKREYKGLV DCTMKTVKNE GFSALYRGFA ISLQTYFIYR
210 220 230 240 250
SVYFGLYDAI RNTINTDKKK LPFYASFAIA QGVTVLSSYL TYPWDTVRRR
260 270 280 290 300
MMVKGQLSTS KAFSAARKIV HEEGVRGLYK GALANIFRSA GGALVMALYE

EIHKHM
Length:306
Mass (Da):34,418
Last modified:November 1, 1996 - v1
Checksum:i05B8E5AD83361A42
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA93110.1.
PIRiT20012.
RefSeqiNP_501803.1. NM_069402.5.
UniGeneiCel.38816.

Genome annotation databases

EnsemblMetazoaiC47E12.2.1; C47E12.2.1; WBGene00008147.
C47E12.2.2; C47E12.2.2; WBGene00008147.
GeneIDi177858.
KEGGicel:CELE_C47E12.2.
UCSCiC47E12.2.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA93110.1.
PIRiT20012.
RefSeqiNP_501803.1. NM_069402.5.
UniGeneiCel.38816.

3D structure databases

ProteinModelPortaliQ18683.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ18683. 1 interactor.
STRINGi6239.C47E12.2.2.

Proteomic databases

EPDiQ18683.
PaxDbiQ18683.
PeptideAtlasiQ18683.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC47E12.2.1; C47E12.2.1; WBGene00008147.
C47E12.2.2; C47E12.2.2; WBGene00008147.
GeneIDi177858.
KEGGicel:CELE_C47E12.2.
UCSCiC47E12.2.1. c. elegans.

Organism-specific databases

CTDi177858.
WormBaseiC47E12.2; CE05446; WBGene00008147.

Phylogenomic databases

eggNOGiKOG0749. Eukaryota.
ENOG410XNW0. LUCA.
GeneTreeiENSGT00390000011543.
HOGENOMiHOG000165727.
InParanoidiQ18683.
KOiK05863.
OMAiADINHHT.
OrthoDBiEOG091G0ULB.
PhylomeDBiQ18683.

Enzyme and pathway databases

ReactomeiR-CEL-422356. Regulation of insulin secretion.

Gene expression databases

BgeeiWBGene00008147.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR002113. Aden_trnslctor.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
PRINTSiPR00927. ADPTRNSLCASE.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ18683_CAEEL
AccessioniPrimary (citable) accession number: Q18683
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: February 15, 2017
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.