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Protein

alpha-1,2-Mannosidase

Gene

C47E12.3

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Enzyme and pathway databases

ReactomeiR-CEL-901032. ER Quality Control Compartment (ERQC).

Protein family/group databases

CAZyiGH47. Glycoside Hydrolase Family 47.

Names & Taxonomyi

Protein namesi
Recommended name:
alpha-1,2-MannosidaseUniRule annotation (EC:3.2.1.-UniRule annotation)
Gene namesi
ORF Names:C47E12.3Imported, CELE_C47E12.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiC47E12.3a; CE33766; WBGene00008148.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 568549alpha-1,2-MannosidaseSequence analysisPRO_5004186866Add
BLAST

Proteomic databases

PaxDbiQ18679.

Expressioni

Gene expression databases

ExpressionAtlasiQ18679. baseline.

Interactioni

Protein-protein interaction databases

STRINGi6239.C47E12.3.2.

Structurei

3D structure databases

ProteinModelPortaliQ18679.
SMRiQ18679. Positions 44-504.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 47 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2429. Eukaryota.
ENOG410XS6F. LUCA.
GeneTreeiENSGT00530000063069.
HOGENOMiHOG000004833.
InParanoidiQ18679.
KOiK10084.
OMAiELLYMAH.
PhylomeDBiQ18679.

Family and domain databases

Gene3Di1.50.10.50. 1 hit.
InterProiIPR001382. Glyco_hydro_47.
[Graphical view]
PfamiPF01532. Glyco_hydro_47. 1 hit.
[Graphical view]
PRINTSiPR00747. GLYHDRLASE47.
SUPFAMiSSF48225. SSF48225. 1 hit.

Sequencei

Sequence statusi: Complete.

Q18679-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFVKNVLIF IALFSTTCSL KTTKNPFLLT KEEIKYASIS DVDLQYGLAK
60 70 80 90 100
TREMFQFGWD NYMEHAFPAD ELDPIHCRGR GHDHDNPDNI NVNDVLGDYS
110 120 130 140 150
LGLIDTLDSL VVFGDADEFK RAVNLVIKTV SFEKNTTVQV FESTIRVMGG
160 170 180 190 200
LLAAHMIAAD KTNRFGPFYM SDYGGELLTL AHDLAGRLLP AFDGTATGIP
210 220 230 240 250
YTRINLQKGI LPGTTNSTCT SGAGSLLLEF GVLSKLLGDD TYERLARRVN
260 270 280 290 300
EKLWNLRNEV TGLHGNLIDI QTGEWLGHLA GLGAGIDSFY EYMLKSYILF
310 320 330 340 350
GNQRDLDMYN ESFARITTYM RRGRSRCSSL EGDIPIYVNV DSRDGSTSNT
360 370 380 390 400
WIDSLQASFA GVLVLAGEVD EAVCHHALYY AIWKKYGVLP ERFNWQLQAP
410 420 430 440 450
DVSFYPLRPE FVESTYLLYT ATKNPFYQHV GLEILDSLET ITRVKCGFAT
460 470 480 490 500
VHDVIDGSLE DRMESFFLSE TLKYLYLLFD VDHPINKEQQ ESVLFSTEGH
510 520 530 540 550
IFPISPLFNL PPTPPSQYDP PLKPLPRTNS SFCETATDFT FGTPPLRHSQ
560
MRELFKVIGV DSVLHDWL
Length:568
Mass (Da):64,000
Last modified:June 1, 2003 - v2
Checksum:i451B660818BD23DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA93106.2.
PIRiT20009.
RefSeqiNP_501802.2. NM_069401.4.
UniGeneiCel.23425.

Genome annotation databases

EnsemblMetazoaiC47E12.3a; C47E12.3a; WBGene00008148.
GeneIDi177857.
KEGGicel:CELE_C47E12.3.
UCSCiC47E12.3. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA93106.2.
PIRiT20009.
RefSeqiNP_501802.2. NM_069401.4.
UniGeneiCel.23425.

3D structure databases

ProteinModelPortaliQ18679.
SMRiQ18679. Positions 44-504.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.C47E12.3.2.

Protein family/group databases

CAZyiGH47. Glycoside Hydrolase Family 47.

Proteomic databases

PaxDbiQ18679.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC47E12.3a; C47E12.3a; WBGene00008148.
GeneIDi177857.
KEGGicel:CELE_C47E12.3.
UCSCiC47E12.3. c. elegans.

Organism-specific databases

CTDi177857.
WormBaseiC47E12.3a; CE33766; WBGene00008148.

Phylogenomic databases

eggNOGiKOG2429. Eukaryota.
ENOG410XS6F. LUCA.
GeneTreeiENSGT00530000063069.
HOGENOMiHOG000004833.
InParanoidiQ18679.
KOiK10084.
OMAiELLYMAH.
PhylomeDBiQ18679.

Enzyme and pathway databases

ReactomeiR-CEL-901032. ER Quality Control Compartment (ERQC).

Gene expression databases

ExpressionAtlasiQ18679. baseline.

Family and domain databases

Gene3Di1.50.10.50. 1 hit.
InterProiIPR001382. Glyco_hydro_47.
[Graphical view]
PfamiPF01532. Glyco_hydro_47. 1 hit.
[Graphical view]
PRINTSiPR00747. GLYHDRLASE47.
SUPFAMiSSF48225. SSF48225. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ18679_CAEEL
AccessioniPrimary (citable) accession number: Q18679
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: June 1, 2003
Last modified: July 6, 2016
This is version 114 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.