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Protein
Submitted name:

Fatty Acid CoA Synthetase family

Gene

acs-17

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-CEL-75876. Synthesis of very long-chain fatty acyl-CoAs.

Names & Taxonomyi

Protein namesi
Submitted name:
Fatty Acid CoA Synthetase familyImported
Gene namesi
Name:acs-17Imported
ORF Names:C46F4.2Imported, CELE_C46F4.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiC46F4.2; CE30907; WBGene00016716; acs-17.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 42HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiQ18660.
PaxDbiQ18660.
PeptideAtlasiQ18660.

Expressioni

Gene expression databases

BgeeiWBGene00016716.

Interactioni

Protein-protein interaction databases

STRINGi6239.C46F4.2.2.

Structurei

3D structure databases

ProteinModelPortaliQ18660.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini130 – 586AMP-bindingInterPro annotationAdd BLAST457
Domaini596 – 681AMP-binding_CInterPro annotationAdd BLAST86

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1256. Eukaryota.
COG1022. LUCA.
GeneTreeiENSGT00690000101725.
HOGENOMiHOG000159459.
InParanoidiQ18660.
KOiK01897.
OMAiMAMSHAC.
OrthoDBiEOG091G02F4.
PhylomeDBiQ18660.

Family and domain databases

InterProiIPR025110. AMP-bd_C.
IPR020459. AMP-binding.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
PRINTSiPR00154. AMPBINDING.
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q18660-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDESDVKSA LNGHDRPFTI TLAIVLLKIV FFIYDVVTFI PFKIFADPAE
60 70 80 90 100
KLEKSERVKA EPDNGDPTTP WKNVSAKDGL MNSSFEGIHD LGTQWEECVR
110 120 130 140 150
RYGNQPCMGT REVLKVHKEK QSNGKIFEKW QMGDYHWRSY AQVDKRVNMI
160 170 180 190 200
ASGLTSLGQQ EKEPIILFAE TREEWMTTAL ACMKMNFPIA TMYATLGDEA
210 220 230 240 250
VQFAINEVGA KTIFTSEALI SKVKKAMSNG ATSIENIIFF DSVDPASRGE
260 270 280 290 300
SVDVDLPFTL LSFDQLLSRG EPYPVPTRSK KDDLAFIMYT SGTTGNPKGV
310 320 330 340 350
MISHQNIVAV TAGQAFNIVL GPDDRYIGYL PLAHILEVCA EMVVFTKGVR
360 370 380 390 400
IGYSSAQTLF DRAPKIMKGE HGDCWVLQPT LMACVPAVMD RIFKAVIDEV
410 420 430 440 450
NANSELFKQL FKTCYERKRS RYEEGYTSFI LNKLVFNRIG KLLGGKVRQI
460 470 480 490 500
LSGGAPLSPE TQRFMNICFC CPVVQGYGLT ETCGGGTIAD IHDLSTGTVG
510 520 530 540 550
PPLTCCEILL QEWAEAGYSP KNDPPQGEIL ISGPNVALGY FKNDEKTKEE
560 570 580 590 600
FVKVNGKTFF ATGDIGEFRE DGSLKIIDRK KDLLKLAHGE YISLGKVETN
610 620 630 640 650
LLTNPNVDNV CVYGDSNKSF LVALVVPNQK NLTQLASKAG ASNDNFEKLC
660 670 680 690 700
EDKKVVEALQ KELAQYGASK LQRVEIPQKI FICHEPWTPA SGLLTEALKL
710
KRKNIEKAFR KELDELYK
Length:718
Mass (Da):79,945
Last modified:October 1, 2002 - v2
Checksum:iA8F7E0FB3A8B6510
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CCD67503.1.
PIRiT15810.
RefSeqiNP_508993.2. NM_076592.6.
UniGeneiCel.17735.

Genome annotation databases

EnsemblMetazoaiC46F4.2.1; C46F4.2.1; WBGene00016716.
C46F4.2.2; C46F4.2.2; WBGene00016716.
GeneIDi180859.
KEGGicel:CELE_C46F4.2.
UCSCiC46F4.2.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CCD67503.1.
PIRiT15810.
RefSeqiNP_508993.2. NM_076592.6.
UniGeneiCel.17735.

3D structure databases

ProteinModelPortaliQ18660.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.C46F4.2.2.

Proteomic databases

EPDiQ18660.
PaxDbiQ18660.
PeptideAtlasiQ18660.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC46F4.2.1; C46F4.2.1; WBGene00016716.
C46F4.2.2; C46F4.2.2; WBGene00016716.
GeneIDi180859.
KEGGicel:CELE_C46F4.2.
UCSCiC46F4.2.1. c. elegans.

Organism-specific databases

CTDi180859.
WormBaseiC46F4.2; CE30907; WBGene00016716; acs-17.

Phylogenomic databases

eggNOGiKOG1256. Eukaryota.
COG1022. LUCA.
GeneTreeiENSGT00690000101725.
HOGENOMiHOG000159459.
InParanoidiQ18660.
KOiK01897.
OMAiMAMSHAC.
OrthoDBiEOG091G02F4.
PhylomeDBiQ18660.

Enzyme and pathway databases

ReactomeiR-CEL-75876. Synthesis of very long-chain fatty acyl-CoAs.

Gene expression databases

BgeeiWBGene00016716.

Family and domain databases

InterProiIPR025110. AMP-bd_C.
IPR020459. AMP-binding.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
PRINTSiPR00154. AMPBINDING.
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ18660_CAEEL
AccessioniPrimary (citable) accession number: Q18660
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: October 1, 2002
Last modified: November 30, 2016
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.