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Protein

Elongation factor Ts

Gene

tsf

Organism
Peptoclostridium difficile (strain 630) (Clostridium difficile)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis

Enzyme and pathway databases

BioCyciPDIF272563:G12WB-2296-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TsUniRule annotation
Short name:
EF-TsUniRule annotation
Gene namesi
Name:tsfUniRule annotation
Ordered Locus Names:CD630_21390
OrganismiPeptoclostridium difficile (strain 630) (Clostridium difficile)
Taxonomic identifieri272563 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaeClostridioides
Proteomesi
  • UP000001978 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000060791 – 303Elongation factor TsAdd BLAST303

Proteomic databases

PRIDEiQ185S9

Interactioni

Protein-protein interaction databases

STRINGi272563.CD2139

Structurei

3D structure databases

ProteinModelPortaliQ185S9
SMRiQ185S9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni82 – 85Involved in Mg(2+) ion dislocation from EF-TuUniRule annotation4

Sequence similaritiesi

Belongs to the EF-Ts family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CU7 Bacteria
COG0264 LUCA
HOGENOMiHOG000220986
KOiK02357
OMAiDAGMMDC

Family and domain databases

Gene3Di3.30.479.20, 3 hits
HAMAPiMF_00050 EF_Ts, 1 hit
InterProiView protein in InterPro
IPR036402 EF-Ts_dimer_sf
IPR001816 Transl_elong_EFTs/EF1B
IPR014039 Transl_elong_EFTs/EF1B_dimer
IPR018101 Transl_elong_Ts_CS
IPR009060 UBA-like_sf
PANTHERiPTHR11741 PTHR11741, 1 hit
PfamiView protein in Pfam
PF00889 EF_TS, 1 hit
SUPFAMiSSF46934 SSF46934, 1 hit
SSF54713 SSF54713, 2 hits
TIGRFAMsiTIGR00116 tsf, 1 hit
PROSITEiView protein in PROSITE
PS01126 EF_TS_1, 1 hit
PS01127 EF_TS_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q185S9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANITAQMVK ELRESTGAGM MDCKKALQEA EGNMEKAVDL LREKGLSKAA
60 70 80 90 100
KKAGRVAAEG LVAIEMNDDN TVASMVEVNS ETDFVAKNED FKVFVKDAAC
110 120 130 140 150
MALATDKEDI ASLLGETHKE GITLQEVLNN RVAKIGEKLD FRRFAKVVTN
160 170 180 190 200
GQVAGYIHGG GKIGVLVEME TEARDAKVLE LGKDVAMQVA AMNPKYVSRD
210 220 230 240 250
EVDAEYIAHE TEVLTQQALN EGKPANIVEK MVKGRLEKEL KEVCLLEQTF
260 270 280 290 300
VKNPDITVKQ LVADVAKAVG SDIKVVKVVR FEVGEGIQKR EENFAEEVAK

QLK
Length:303
Mass (Da):33,140
Last modified:July 25, 2006 - v1
Checksum:iA957376BAF89E8D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA Translation: CAJ69024.1
RefSeqiWP_003424535.1, NZ_CP010905.2
YP_001088653.1, NC_009089.1

Genome annotation databases

EnsemblBacteriaiCAJ69024; CAJ69024; CD630_21390
GeneIDi31353733
4913119
KEGGicdf:CD630_21390
pdc:CDIF630_02370
PATRICifig|272563.120.peg.2259

Similar proteinsi

Entry informationi

Entry nameiEFTS_PEPD6
AccessioniPrimary (citable) accession number: Q185S9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 25, 2006
Last modified: May 23, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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