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Protein

Elongation factor Ts

Gene

tsf

Organism
Peptoclostridium difficile (strain 630) (Clostridium difficile)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-2349-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TsUniRule annotation
Short name:
EF-TsUniRule annotation
Gene namesi
Name:tsfUniRule annotation
Ordered Locus Names:CD630_21390
OrganismiPeptoclostridium difficile (strain 630) (Clostridium difficile)
Taxonomic identifieri272563 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium
Proteomesi
  • UP000001978 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 303303Elongation factor TsPRO_1000006079Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272563.CD2139.

Structurei

3D structure databases

ProteinModelPortaliQ185S9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni82 – 854Involved in Mg(2+) ion dislocation from EF-TuUniRule annotation

Sequence similaritiesi

Belongs to the EF-Ts family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CU7. Bacteria.
COG0264. LUCA.
HOGENOMiHOG000220986.
KOiK02357.
OMAiATYIHNA.

Family and domain databases

Gene3Di3.30.479.20. 3 hits.
HAMAPiMF_00050. EF_Ts. 1 hit.
InterProiIPR001816. Transl_elong_EFTs/EF1B.
IPR014039. Transl_elong_EFTs/EF1B_dimer.
IPR018101. Transl_elong_Ts_CS.
IPR009060. UBA-like.
[Graphical view]
PANTHERiPTHR11741. PTHR11741. 1 hit.
PfamiPF00889. EF_TS. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54713. SSF54713. 2 hits.
TIGRFAMsiTIGR00116. tsf. 1 hit.
PROSITEiPS01126. EF_TS_1. 1 hit.
PS01127. EF_TS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q185S9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANITAQMVK ELRESTGAGM MDCKKALQEA EGNMEKAVDL LREKGLSKAA
60 70 80 90 100
KKAGRVAAEG LVAIEMNDDN TVASMVEVNS ETDFVAKNED FKVFVKDAAC
110 120 130 140 150
MALATDKEDI ASLLGETHKE GITLQEVLNN RVAKIGEKLD FRRFAKVVTN
160 170 180 190 200
GQVAGYIHGG GKIGVLVEME TEARDAKVLE LGKDVAMQVA AMNPKYVSRD
210 220 230 240 250
EVDAEYIAHE TEVLTQQALN EGKPANIVEK MVKGRLEKEL KEVCLLEQTF
260 270 280 290 300
VKNPDITVKQ LVADVAKAVG SDIKVVKVVR FEVGEGIQKR EENFAEEVAK

QLK
Length:303
Mass (Da):33,140
Last modified:July 25, 2006 - v1
Checksum:iA957376BAF89E8D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ69024.1.
RefSeqiWP_003424535.1. NZ_CP010905.1.
YP_001088653.1. NC_009089.1.

Genome annotation databases

EnsemblBacteriaiCAJ69024; CAJ69024; CD630_21390.
GeneIDi4913119.
KEGGicdf:CD630_21390.
pdc:CDIF630_02370.
PATRICi19442731. VBICloDif38397_2252.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ69024.1.
RefSeqiWP_003424535.1. NZ_CP010905.1.
YP_001088653.1. NC_009089.1.

3D structure databases

ProteinModelPortaliQ185S9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272563.CD2139.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ69024; CAJ69024; CD630_21390.
GeneIDi4913119.
KEGGicdf:CD630_21390.
pdc:CDIF630_02370.
PATRICi19442731. VBICloDif38397_2252.

Phylogenomic databases

eggNOGiENOG4105CU7. Bacteria.
COG0264. LUCA.
HOGENOMiHOG000220986.
KOiK02357.
OMAiATYIHNA.

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-2349-MONOMER.

Family and domain databases

Gene3Di3.30.479.20. 3 hits.
HAMAPiMF_00050. EF_Ts. 1 hit.
InterProiIPR001816. Transl_elong_EFTs/EF1B.
IPR014039. Transl_elong_EFTs/EF1B_dimer.
IPR018101. Transl_elong_Ts_CS.
IPR009060. UBA-like.
[Graphical view]
PANTHERiPTHR11741. PTHR11741. 1 hit.
PfamiPF00889. EF_TS. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54713. SSF54713. 2 hits.
TIGRFAMsiTIGR00116. tsf. 1 hit.
PROSITEiPS01126. EF_TS_1. 1 hit.
PS01127. EF_TS_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiEFTS_PEPD6
AccessioniPrimary (citable) accession number: Q185S9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 25, 2006
Last modified: September 7, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.