Q185K5 (Q185K5_CLOD6) Unreviewed, UniProtKB/TrEMBL
Last modified
December 14, 2011.
Version 43.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Mannitol-1-phosphate 5-dehydrogenase HAMAP MF_00196 EC=1.1.1.17 HAMAP MF_00196 | ||||
| Gene names |
| ||||
| Organism | Clostridium difficile (strain 630) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 272563 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium |
Protein attributes
| Sequence length | 383 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH. HAMAP MF_00196 SAAS SAAS000669 |
| Sequence similarities | Belongs to the mannitol dehydrogenase family. HAMAP MF_00196 |
Ontologies
| Keywords | |
|---|---|
| Ligand | NAD HAMAP MF_00196 SAAS SAAS000669 |
| Molecular function | Oxidoreductase HAMAP MF_00196 SAAS SAAS023028 EMBL CAJ69218.1 |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Molecular function | coenzyme binding Inferred from electronic annotation. Source: InterPro mannitol-1-phosphate 5-dehydrogenase activityInferred from electronic annotation. Source: HAMAP nucleotide bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Regions | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Nucleotide binding | 4 – 15 | 12 | NAD By similarity HAMAP MF_00196 | ||||||
Sequences
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References
| [1] | "The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome." Sebaihia M., Wren B.W., Mullany P., Fairweather N.F., Minton N., Stabler R., Thomson N.R., Roberts A.P., Cerdeno-Tarraga A.M., Wang H., Holden M.T.G., Wright A., Churcher C., Quail M.A., Baker S., Bason N., Brooks K., Chillingworth T. Parkhill J.Nat. Genet. 38:779-786(2006) [PubMed: 16804543] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 630. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AM180355 Genomic DNA. Translation: CAJ69218.1. |
| RefSeq | YP_001088846.1. NC_009089.1. |
3D structure databases | |
| ProteinModelPortal | Q185K5. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q185K5. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 4914174. |
| GenomeReviews | Gene locus CD2331 in contig AM180355_GR. |
| KEGG | cdf:CD2331. |
| NMPDR | fig|1496.1.peg.2520. |
| PATRIC | 19443123. VBICloDif38397_2448. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0246. |
| HOGENOM | HBG568825. |
| OMA | FANTAVD. |
| ProtClustDB | CLSK853027. |
Family and domain databases | |
| HAMAP | MF_00196. Mannitol_dehydrog. [Tree] |
| InterPro | IPR008927. 6-PGluconate_DH_C-like. IPR013328. DH_multihelical. IPR023028. Mannitol_1_phos_5_DH. IPR000669. Mannitol_DH. IPR013118. Mannitol_DH_C. IPR023027. Mannitol_DH_CS. IPR013131. Mannitol_DH_N. IPR016040. NAD(P)-bd_dom. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit. |
| KO | K00009. |
| Pfam | PF01232. Mannitol_dh. 1 hit. PF08125. Mannitol_dh_C. 1 hit. [Graphical view] |
| PRINTS | PR00084. MTLDHDRGNASE. |
| SUPFAM | SSF48179. 6DGDH_C_like. 1 hit. |
| PROSITE | PS00974. MANNITOL_DHGENASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | Q185K5_CLOD6 | ||||||||
| Accession | Primary (citable) accession number: Q185K5 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

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