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Q185K5 (Q185K5_CLOD6) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannitol-1-phosphate 5-dehydrogenase HAMAP MF_00196

EC=1.1.1.17 HAMAP MF_00196
Gene names
Name:mtlD HAMAP MF_00196 EMBL CAJ69218.1
Ordered Locus Names:CD630_23310
OrganismClostridium difficile (strain 630) [Complete proteome] [HAMAP]
Taxonomic identifier272563 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length383 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH. HAMAP MF_00196 SAAS SAAS000669

Sequence similarities

Belongs to the mannitol dehydrogenase family. HAMAP MF_00196

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding4 – 1512NAD By similarity HAMAP MF_00196

Sequences

Sequence LengthMass (Da)Tools
Q185K5 [UniParc].

Last modified July 25, 2006. Version 1.
Checksum: C137DCF00F5E916F

FASTA38342,969
        10         20         30         40         50         60 
MKKAIQFGAG NIGRGFIGGL LVKSGYHVVF ADVNEYILNS INKDKKYTIH IRDVECIDEV 

        70         80         90        100        110        120 
IDNISAVSSI KEEIIDEIVQ AEIITTAVGP LVLTKIASTI AKGIKARKEK GLTSNLNIIA 

       130        140        150        160        170        180 
CENAIYASSS LKEEVLKYLN KEEVEYLEMY VGFPNCSVDR IVPPGKNENP LDVTVENFYE 

       190        200        210        220        230        240 
WNVEKQGFKG EIPTIVGMNL ADNLMAYIER KLFTLNTGHA ITAYIGYLKG YKTIEESIKD 

       250        260        270        280        290        300 
KFICDIVKSA MVESGEGLIK KYNFDSEVHY KYIDKILNRF KNPYLNDDVL RVGREPLRKL 

       310        320        330        340        350        360 
SDKDRLIKPL MTAKSYGLSV DNLILGIGAA LHYNNSEDTQ SVELQELIKS IGVKKAVAKI 

       370        380 
ANISNDEELL NNIEKSYIFM KNL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM180355 Genomic DNA. Translation: CAJ69218.1.
RefSeqYP_001088846.1. NC_009089.1.

3D structure databases

ProteinModelPortalQ185K5.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ185K5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4914174.
GenomeReviewsGene locus CD2331 in contig AM180355_GR.
KEGGcdf:CD2331.
NMPDRfig|1496.1.peg.2520.
PATRIC19443123. VBICloDif38397_2448.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0246.
HOGENOMHBG568825.
OMAFANTAVD.
ProtClustDBCLSK853027.

Family and domain databases

HAMAPMF_00196. Mannitol_dehydrog.
[Tree]
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR023028. Mannitol_1_phos_5_DH.
IPR000669. Mannitol_DH.
IPR013118. Mannitol_DH_C.
IPR023027. Mannitol_DH_CS.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KOK00009.
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
PRINTSPR00084. MTLDHDRGNASE.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
PROSITEPS00974. MANNITOL_DHGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ185K5_CLOD6
AccessionPrimary (citable) accession number: Q185K5
Entry history
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)