Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q184E7 (VATA_CLOD6) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
V-type ATP synthase alpha chain

EC=3.6.3.14
Alternative name(s):
V-ATPase subunit A
Gene names
Name:atpA
Ordered Locus Names:CD630_29560
OrganismClostridium difficile (strain 630) [Complete proteome] [HAMAP]
Taxonomic identifier272563 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceae

Protein attributes

Sequence length592 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit By similarity. HAMAP-Rule MF_00309

Catalytic activity

ATP + H2O + H+(In) = ADP + phosphate + H+(Out). HAMAP-Rule MF_00309

Sequence similarities

Belongs to the ATPase alpha/beta chains family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 592592V-type ATP synthase alpha chain HAMAP-Rule MF_00309
PRO_0000322463

Regions

Nucleotide binding232 – 2398ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q184E7 [UniParc].

Last modified July 25, 2006. Version 1.
Checksum: EA32CAD099CE02F6

FASTA59265,526
        10         20         30         40         50         60 
MKTGTIVKVS GPLVVAEGMR DANMFDVVRV SDKHLIGEII EMHGDKASIQ VYEETSGLGP 

        70         80         90        100        110        120 
GEEVVSLGMP MSVELGPGLI STIYDGIQRP LEKMYDISGT NITKGVEVSS LDRTTKWEFK 

       130        140        150        160        170        180 
PKKSVGDKVV AGDIIGGVQE TAVVECKIMV PYGVKGTIKE IYSGEFTVED TVCVITDEKG 

       190        200        210        220        230        240 
NDIPVTMMQK WPVRKERPYR EKKTPDSLLV TGQRVIDTFF PITKGGVAAI PGPFGSGKTV 

       250        260        270        280        290        300 
TQHQLAKWAD ADIVVYIGCG ERGNEMTDVL LEFPELKDPR TGESLMQRTV LIANTSDMPV 

       310        320        330        340        350        360 
AAREASIYTG ITIAEYFRDM GYSVALMADS TSRWAEALRE MSGRLEEMPG EEGYPAYLGS 

       370        380        390        400        410        420 
RLAQFYERAG KVNCLGMDER EGTLTAIGAV SPPGGDTSEP VSQATLRIVK VFWGLDASLA 

       430        440        450        460        470        480 
YKRHFPAINW LTSYSLYQEK VDVWADKNVN DNFSAQRAQA MKLLQVESEL QEIVQLVGVD 

       490        500        510        520        530        540 
SLSDGDRLIL EVTRSIREDF LHQNSFHEVD TYTSLHKQYR MMGLILKFYK SAQDAIKQNV 

       550        560        570        580        590 
TINDIIKLSV LEKIGRAKYV EEGDIDAAYD SIEDEIDNEL ADLIKKRGAE EL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM180355 Genomic DNA. Translation: CAJ69848.1.
RefSeqYP_001089472.1. NC_009089.1.

3D structure databases

ProteinModelPortalQ184E7.
SMRQ184E7. Positions 60-589.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272563.CD2956.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ69848; CAJ69848; CD630_29560.
GeneID4913755.
KEGGcdf:CD630_29560.
PATRIC19444433. VBICloDif38397_3100.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1155.
HOGENOMHOG000161057.
KOK02117.
OMAVNTSNMP.
OrthoDBEOG6CP3V3.
ProtClustDBPRK04192.

Enzyme and pathway databases

BioCycCDIF272563:GJFE-3189-MONOMER.

Family and domain databases

Gene3D1.10.1140.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPMF_00309. ATP_synth_A_arch.
InterProIPR003593. AAA+_ATPase.
IPR020003. ATPase_a/bsu_AS.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR004100. ATPase_F1_a/bsu_N.
IPR024034. ATPase_F1_bsu/V1_C.
IPR027417. P-loop_NTPase.
IPR022878. V-ATPase_asu.
[Graphical view]
PfamPF00006. ATP-synt_ab. 1 hit.
PF00306. ATP-synt_ab_C. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF47917. SSF47917. 1 hit.
SSF50615. SSF50615. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameVATA_CLOD6
AccessionPrimary (citable) accession number: Q184E7
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: July 25, 2006
Last modified: April 16, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families