Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Acetyl-coenzyme A synthetase

Gene

acs-19

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-CEL-71384 Ethanol oxidation

Names & Taxonomyi

Protein namesi
Recommended name:
Acetyl-coenzyme A synthetaseUniRule annotation (EC:6.2.1.1UniRule annotation)
Gene namesi
Name:acs-19Imported
ORF Names:C36A4.9Imported, CELE_C36A4.9Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiC36A4.9a ; CE03076 ; WBGene00007969 ; acs-19

PTM / Processingi

Proteomic databases

EPDiQ18496
PaxDbiQ18496
PeptideAtlasiQ18496

Expressioni

Gene expression databases

BgeeiWBGene00007969
ExpressionAtlasiQ18496 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi6239.C36A4.9a.1

Structurei

3D structure databases

ProteinModelPortaliQ18496
SMRiQ18496
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 99ACAS_NInterPro annotationAdd BLAST60
Domaini106 – 553AMP-bindingInterPro annotationAdd BLAST448
Domaini562 – 640AMP-binding_CInterPro annotationAdd BLAST79

Sequence similaritiesi

Belongs to the ATP-dependent AMP-binding enzyme family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1175 Eukaryota
COG0365 LUCA
GeneTreeiENSGT00760000119178
HOGENOMiHOG000229981
InParanoidiQ18496
KOiK01895
OMAiDHWWHDL
OrthoDBiEOG091G039C
PhylomeDBiQ18496

Family and domain databases

CDDicd05966 ACS, 1 hit
InterProiView protein in InterPro
IPR011904 Ac_CoA_lig
IPR032387 ACAS_N
IPR025110 AMP-bd_C
IPR020845 AMP-binding_CS
IPR000873 AMP-dep_Synth/Lig
PfamiView protein in Pfam
PF16177 ACAS_N, 1 hit
PF00501 AMP-binding, 1 hit
PF13193 AMP-binding_C, 1 hit
TIGRFAMsiTIGR02188 Ac_CoA_lig_AcsA, 1 hit
PROSITEiView protein in PROSITE
PS00455 AMP_BINDING, 1 hit

Sequencei

Sequence statusi: Complete.

Q18496-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDVRVKFNL ANDGEGLDED IFLPPAPLLA GAHCAGLQSY HDLYRSSIND
60 70 80 90 100
ADEFWRTVSS ELHFEQGTSK GLEWNFDSKA GNVFVKFMDG AKTNISYNCL
110 120 130 140 150
ERNIKRGYGN KIAYIFEGNE PTDTSTWTYN ELHAQVVQFS AVLRSHGVKR
160 170 180 190 200
GDVVALYLPM IPELAVAMLA CARIGAMHSV VFAGFSAESL AARVVDARCR
210 220 230 240 250
VLVTADGVFR GAKPIGLKSI ADAAAVLASQ EDVKVEAIIM VEHLKRVTKP
260 270 280 290 300
DGVELPKVDY TDITVIYDSE MLKCAGVDSP VEWMDSEDPL FILYTSGSTG
310 320 330 340 350
KPKGIQHTTA GYMTYAYATT KYTFDAQEDD VYWCTADCGW ITGHSYLLYG
360 370 380 390 400
PLMNGLKGIW YEGVPTYPTP SRMWDVTDKY GVTKLYTSPT AARALMALGN
410 420 430 440 450
QWLESSSRKT LKVIGTVGEP INPAAWMWLY KQVGLSNVSI VDTYWQTETG
460 470 480 490 500
GHMITCLPGA TPMKPGAAAM PFFGASPVLL DAEGRVIEGP GEGSLCFDRA
510 520 530 540 550
WPGMMRGIYG DEQRFVKTYL APFNGYYFTG DGARRDEDGY LWITGRVDDL
560 570 580 590 600
MNVSGHLLST AEIESALVAH EKVAEAAVVA APHDIKGSFP YAFVTLNVGE
610 620 630 640 650
RINEKLVAEL KKLVREKIGA LAVPDVIQEA PGLPKTRSGK VTRRILRKIA
660 670 680
EGSESGIGDT TTLVDESVIK QLISGRSARA
Length:680
Mass (Da):74,350
Last modified:November 1, 1996 - v1
Checksum:i8ABA18382CF4C1AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA Translation: CAA91274.1
PIRiT19768
RefSeqiNP_001021205.1, NM_001026034.3
UniGeneiCel.17802

Genome annotation databases

EnsemblMetazoaiC36A4.9a.1; C36A4.9a.1; WBGene00007969
C36A4.9a.2; C36A4.9a.2; WBGene00007969
GeneIDi175500
KEGGicel:CELE_C36A4.9
UCSCiC36A4.9a.3 c. elegans

Similar proteinsi

Entry informationi

Entry nameiQ18496_CAEEL
AccessioniPrimary (citable) accession number: Q18496
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health