Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Peptoclostridium difficile (strain 630) (Clostridium difficile)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a chaperone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-2679-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaKUniRule annotation
Alternative name(s):
HSP70UniRule annotation
Heat shock 70 kDa proteinUniRule annotation
Heat shock protein 70UniRule annotation
Gene namesi
Name:dnaKUniRule annotation
Ordered Locus Names:CD630_24610
OrganismiPeptoclostridium difficile (strain 630) (Clostridium difficile)
Taxonomic identifieri272563 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium
Proteomesi
  • UP000001978 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 615615Chaperone protein DnaKPRO_1000059542Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei175 – 1751Phosphothreonine; by autocatalysisUniRule annotation

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ182E8.

Expressioni

Inductioni

By stress conditions e.g. heat shock.UniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi272563.CD2461.

Structurei

3D structure databases

ProteinModelPortaliQ182E8.
SMRiQ182E8. Positions 1-506.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228135.
KOiK04043.
OMAiEMMYKDA.
OrthoDBiEOG6JMMSV.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q182E8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKIIGIDLG TTNSCVAVLE GGEAQIIANS EGMRTTPSVV AFTKDGERIV
60 70 80 90 100
GEPAKRQAVT NADKTITSIK THMGTDYKVN IDGKSYTPQE ISAIILQKLK
110 120 130 140 150
SDAESYLGQT VTEAVITVPA YFTDAQRQAT KDAGRIAGLD VKRIINEPTA
160 170 180 190 200
AALAYGMDKL DQEKKILVFD LGGGTFDVSI LEIGDGTFEV LATAGNNRLG
210 220 230 240 250
GDDFDQIVID YLAEEFKKAE GVDLRNDKMA LQRLKEAAEK AKKELSSTMS
260 270 280 290 300
SNINLPFITA TAEGPKHLNI DLSRAKFEEL TRGLVEKTME PTKTALQDAG
310 320 330 340 350
LSTGDIDDVL LVGGSTRIPA VQEAVKKFIG KEPHKGINPD ECVAAGASIQ
360 370 380 390 400
AGVLAGDVKD LLLLDVTPLS LGIETMGNVM TKIIERNTTI PTKKSQIFST
410 420 430 440 450
AADNQTAVDI HVLQGERSMA YDNTTLGRFQ LTDIPPAQRG IPQIEVTFDI
460 470 480 490 500
DANGIVNVSA KDLGTGKEQK ITITSNTNLS EAEIEQKIKE AEMNAEADKQ
510 520 530 540 550
KKEKIEAFNQ AESTIYQTEK TLNELGDKIS SGEKEDIEKA IADLKAVKDN
560 570 580 590 600
QDATAEELKK ATDEVMTKFQ KVSQEMYQKA AQEQQAAQGA EQAQDNGPKD
610
DNVVDADFKE VDEDK
Length:615
Mass (Da):66,468
Last modified:July 25, 2006 - v1
Checksum:iB322FD9AB0BF986E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ69348.1.
RefSeqiWP_003430934.1. NZ_CP010905.1.
YP_001088975.1. NC_009089.1.

Genome annotation databases

EnsemblBacteriaiCAJ69348; CAJ69348; CD630_24610.
GeneIDi4916451.
KEGGicdf:CD630_24610.
pdc:CDIF630_02707.
PATRICi19443393. VBICloDif38397_2583.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ69348.1.
RefSeqiWP_003430934.1. NZ_CP010905.1.
YP_001088975.1. NC_009089.1.

3D structure databases

ProteinModelPortaliQ182E8.
SMRiQ182E8. Positions 1-506.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272563.CD2461.

Proteomic databases

PRIDEiQ182E8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ69348; CAJ69348; CD630_24610.
GeneIDi4916451.
KEGGicdf:CD630_24610.
pdc:CDIF630_02707.
PATRICi19443393. VBICloDif38397_2583.

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228135.
KOiK04043.
OMAiEMMYKDA.
OrthoDBiEOG6JMMSV.

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-2679-MONOMER.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 630.

Entry informationi

Entry nameiDNAK_PEPD6
AccessioniPrimary (citable) accession number: Q182E8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 25, 2006
Last modified: November 11, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.