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Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Peptoclostridium difficile (strain 630) (Clostridium difficile)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Acts as a chaperone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPDIF272563:G12WB-2616-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaKUniRule annotation
Alternative name(s):
HSP70UniRule annotation
Heat shock 70 kDa proteinUniRule annotation
Heat shock protein 70UniRule annotation
Gene namesi
Name:dnaKUniRule annotation
Ordered Locus Names:CD630_24610
OrganismiPeptoclostridium difficile (strain 630) (Clostridium difficile)
Taxonomic identifieri272563 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaeClostridioides
Proteomesi
  • UP000001978 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000595421 – 615Chaperone protein DnaKAdd BLAST615

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei175Phosphothreonine; by autocatalysisUniRule annotation1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ182E8

Expressioni

Inductioni

By stress conditions e.g. heat shock.UniRule annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi272563.CD2461

Structurei

3D structure databases

ProteinModelPortaliQ182E8
SMRiQ182E8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CFG Bacteria
COG0443 LUCA
HOGENOMiHOG000228135
KOiK04043
OMAiISIKRHM

Family and domain databases

Gene3Di1.20.1270.10, 1 hit
2.60.34.10, 1 hit
HAMAPiMF_00332 DnaK, 1 hit
InterProiView protein in InterPro
IPR012725 Chaperone_DnaK
IPR018181 Heat_shock_70_CS
IPR029048 HSP70_C_sf
IPR029047 HSP70_peptide-bd_sf
IPR013126 Hsp_70_fam
PANTHERiPTHR19375 PTHR19375, 2 hits
PfamiView protein in Pfam
PF00012 HSP70, 1 hit
PRINTSiPR00301 HEATSHOCK70
SUPFAMiSSF100920 SSF100920, 1 hit
SSF100934 SSF100934, 1 hit
TIGRFAMsiTIGR02350 prok_dnaK, 1 hit
PROSITEiView protein in PROSITE
PS00297 HSP70_1, 1 hit
PS00329 HSP70_2, 1 hit
PS01036 HSP70_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q182E8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKIIGIDLG TTNSCVAVLE GGEAQIIANS EGMRTTPSVV AFTKDGERIV
60 70 80 90 100
GEPAKRQAVT NADKTITSIK THMGTDYKVN IDGKSYTPQE ISAIILQKLK
110 120 130 140 150
SDAESYLGQT VTEAVITVPA YFTDAQRQAT KDAGRIAGLD VKRIINEPTA
160 170 180 190 200
AALAYGMDKL DQEKKILVFD LGGGTFDVSI LEIGDGTFEV LATAGNNRLG
210 220 230 240 250
GDDFDQIVID YLAEEFKKAE GVDLRNDKMA LQRLKEAAEK AKKELSSTMS
260 270 280 290 300
SNINLPFITA TAEGPKHLNI DLSRAKFEEL TRGLVEKTME PTKTALQDAG
310 320 330 340 350
LSTGDIDDVL LVGGSTRIPA VQEAVKKFIG KEPHKGINPD ECVAAGASIQ
360 370 380 390 400
AGVLAGDVKD LLLLDVTPLS LGIETMGNVM TKIIERNTTI PTKKSQIFST
410 420 430 440 450
AADNQTAVDI HVLQGERSMA YDNTTLGRFQ LTDIPPAQRG IPQIEVTFDI
460 470 480 490 500
DANGIVNVSA KDLGTGKEQK ITITSNTNLS EAEIEQKIKE AEMNAEADKQ
510 520 530 540 550
KKEKIEAFNQ AESTIYQTEK TLNELGDKIS SGEKEDIEKA IADLKAVKDN
560 570 580 590 600
QDATAEELKK ATDEVMTKFQ KVSQEMYQKA AQEQQAAQGA EQAQDNGPKD
610
DNVVDADFKE VDEDK
Length:615
Mass (Da):66,468
Last modified:July 25, 2006 - v1
Checksum:iB322FD9AB0BF986E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA Translation: CAJ69348.1
RefSeqiWP_003430934.1, NZ_CP010905.2
YP_001088975.1, NC_009089.1

Genome annotation databases

EnsemblBacteriaiCAJ69348; CAJ69348; CD630_24610
GeneIDi31354059
4916451
KEGGicdf:CD630_24610
pdc:CDIF630_02707
PATRICifig|272563.120.peg.2600

Similar proteinsi

Entry informationi

Entry nameiDNAK_PEPD6
AccessioniPrimary (citable) accession number: Q182E8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 25, 2006
Last modified: May 23, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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