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Protein
Submitted name:

Putative histidine triad (HIT) protein

Gene

CD630_24470

Organism
Peptoclostridium difficile (strain 630) (Clostridium difficile)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi3 – 31ZincCombined sources
Metal bindingi6 – 61ZincCombined sources
Metal bindingi45 – 451Zinc; via pros nitrogenCombined sources
Metal bindingi97 – 971Zinc; via pros nitrogenCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-bindingCombined sources, ZincCombined sources

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-2665-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative histidine triad (HIT) proteinImported
Gene namesi
Ordered Locus Names:CD630_24470Imported
OrganismiPeptoclostridium difficile (strain 630) (Clostridium difficile)Imported
Taxonomic identifieri272563 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium
Proteomesi
  • UP000001978 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi272563.CD2447.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4EGUX-ray0.95A/B1-116[»]
ProteinModelPortaliQ182D4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 113110HITInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4105K59. Bacteria.
COG0537. LUCA.
HOGENOMiHOG000061064.
KOiK02503.
OMAiCNPYPDG.
OrthoDBiEOG69GZSV.

Family and domain databases

Gene3Di3.30.428.10. 1 hit.
InterProiIPR001310. Histidine_triad_HIT.
IPR011146. HIT-like.
[Graphical view]
PANTHERiPTHR23089. PTHR23089. 1 hit.
PfamiPF01230. HIT. 1 hit.
[Graphical view]
PRINTSiPR00332. HISTRIAD.
SUPFAMiSSF54197. SSF54197. 1 hit.
PROSITEiPS51084. HIT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q182D4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDCIFCKIAN GEIPSTKVYE DDRVLAFNDL NPVAPYHILV VPKKHYDSLI
60 70 80 90 100
DIPDKEMDIV SHIHVVINKI AKEKGFDQTG FRVINNCGSD GGQEVKHLHY
110
HILAGKKLPN YEAGQN
Length:116
Mass (Da):13,057
Last modified:July 25, 2006 - v1
Checksum:iDDD2A8A85F5B2B1C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ69334.1.
RefSeqiWP_003430911.1. NZ_CP010905.1.
YP_001088961.1. NC_009089.1.

Genome annotation databases

EnsemblBacteriaiCAJ69334; CAJ69334; CD630_24470.
GeneIDi4914557.
KEGGicdf:CD630_24470.
pdc:CDIF630_02692.
PATRICi19443363. VBICloDif38397_2568.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ69334.1.
RefSeqiWP_003430911.1. NZ_CP010905.1.
YP_001088961.1. NC_009089.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4EGUX-ray0.95A/B1-116[»]
ProteinModelPortaliQ182D4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272563.CD2447.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ69334; CAJ69334; CD630_24470.
GeneIDi4914557.
KEGGicdf:CD630_24470.
pdc:CDIF630_02692.
PATRICi19443363. VBICloDif38397_2568.

Phylogenomic databases

eggNOGiENOG4105K59. Bacteria.
COG0537. LUCA.
HOGENOMiHOG000061064.
KOiK02503.
OMAiCNPYPDG.
OrthoDBiEOG69GZSV.

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-2665-MONOMER.

Family and domain databases

Gene3Di3.30.428.10. 1 hit.
InterProiIPR001310. Histidine_triad_HIT.
IPR011146. HIT-like.
[Graphical view]
PANTHERiPTHR23089. PTHR23089. 1 hit.
PfamiPF01230. HIT. 1 hit.
[Graphical view]
PRINTSiPR00332. HISTRIAD.
SUPFAMiSSF54197. SSF54197. 1 hit.
PROSITEiPS51084. HIT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 630Imported.
  2. "0.95A Resolution Structure of a Histidine Triad Protein from Clostridium difficile."
    Anderson S.M., Wawrzak Z., Kudritska M., Peterson S.N., Anderson W.F., Savchenko A.
    Submitted (APR-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (0.95 ANGSTROMS) IN COMPLEX WITH ZINC.

Entry informationi

Entry nameiQ182D4_PEPD6
AccessioniPrimary (citable) accession number: Q182D4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: May 11, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.