Q180W4 (Q180W4_CLOD6) Unreviewed, UniProtKB/TrEMBL
Last modified
December 14, 2011.
Version 45.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Holo-[acyl-carrier-protein] synthase HAMAP MF_00101 Short name=Holo-ACP synthase HAMAP MF_00101 EC=2.7.8.7 HAMAP MF_00101 Alternative name(s): 4'-phosphopantetheinyl transferase AcpS HAMAP MF_00101 | ||||
| Gene names |
| ||||
| Organism | Clostridium difficile (strain 630) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 272563 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium |
Protein attributes
| Sequence length | 126 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein By similarity. HAMAP MF_00101 |
| Catalytic activity | CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein]. HAMAP MF_00101 |
| Cofactor | Magnesium By similarity. HAMAP MF_00101 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00101. |
| Sequence similarities | Belongs to the P-Pant transferase superfamily. AcpS family. HAMAP MF_00101 |
Ontologies
| Keywords | |
|---|---|
| Biological process | Fatty acid biosynthesis HAMAP MF_00101 Lipid synthesis |
| Cellular component | Cytoplasm HAMAP MF_00101 |
| Ligand | Magnesium HAMAP MF_00101 Metal-binding HAMAP MF_00101 |
| Molecular function | Transferase HAMAP MF_00101 EMBL CAJ70369.1 |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | fatty acid biosynthetic process Inferred from electronic annotation. Source: HAMAP macromolecule biosynthetic processInferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | holo-[acyl-carrier-protein] synthase activity Inferred from electronic annotation. Source: HAMAP magnesium ion bindingInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Sites | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Metal binding | 9 | 1 | Magnesium By similarity HAMAP MF_00101 | ||||||
| Metal binding | 57 | 1 | Magnesium By similarity HAMAP MF_00101 | ||||||
Sequences
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References
| [1] | "The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome." Sebaihia M., Wren B.W., Mullany P., Fairweather N.F., Minton N., Stabler R., Thomson N.R., Roberts A.P., Cerdeno-Tarraga A.M., Wang H., Holden M.T.G., Wright A., Churcher C., Quail M.A., Baker S., Bason N., Brooks K., Chillingworth T. Parkhill J.Nat. Genet. 38:779-786(2006) [PubMed: 16804543] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 630. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AM180355 Genomic DNA. Translation: CAJ70369.1. |
| RefSeq | YP_001089986.1. NC_009089.1. |
3D structure databases | |
| ProteinModelPortal | Q180W4. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q180W4. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 4914800. |
| GenomeReviews | Gene locus CD3466 in contig AM180355_GR. |
| KEGG | cdf:CD3466. |
| NMPDR | fig|1496.1.peg.1120. |
| PATRIC | 19445501. VBICloDif38397_3631. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0736. |
| HOGENOM | HBG734479. |
| OMA | NSSAIAY. |
| ProtClustDB | PRK00070. |
Family and domain databases | |
| HAMAP | MF_00101. AcpS. [Tree] |
| InterPro | IPR008278. 4-PPantetheinyl_Trfase. IPR002582. ACPS. IPR004568. PPantethiene-prot_Trfase. [Graphical view] |
| Gene3D | G3DSA:3.90.470.20. G3DSA:3.90.470.20. 1 hit. |
| KO | K00997. |
| Pfam | PF01648. ACPS. 1 hit. [Graphical view] |
| ProDom | PD004282. PPantethiene-prot_Trfase. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| SUPFAM | SSF56214. 4-PPT_transf. 1 hit. |
| TIGRFAMs | TIGR00516. AcpS. 1 hit. TIGR00556. Pantethn_trn. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | Q180W4_CLOD6 | ||||||||
| Accession | Primary (citable) accession number: Q180W4 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

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