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Protein

Putative sporulation transcription regulator WhiA

Gene

whiA

Organism
Peptoclostridium difficile (strain 630) (Clostridium difficile)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be required for sporulation.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi280 – 31334H-T-H motifUniRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-3651-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative sporulation transcription regulator WhiAUniRule annotation
Gene namesi
Name:whiAUniRule annotation
Ordered Locus Names:CD630_33970
OrganismiPeptoclostridium difficile (strain 630) (Clostridium difficile)
Taxonomic identifieri272563 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium
Proteomesi
  • UP000001978 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 315315Putative sporulation transcription regulator WhiAPRO_0000376464Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272563.CD3397.

Family & Domainsi

Sequence similaritiesi

Belongs to the WhiA transcriptional regulatory family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CIE. Bacteria.
COG1481. LUCA.
HOGENOMiHOG000040187.
KOiK09762.
OrthoDBiEOG68WR87.

Family and domain databases

Gene3Di3.10.28.10. 1 hit.
HAMAPiMF_01420. HTH_type_WhiA.
InterProiIPR027434. Homing_endonucl.
IPR004042. Intein_endonuc.
IPR018478. Sporu_reg_WhiA_N_dom.
IPR003802. Sporulation_regulator_WhiA.
IPR023054. Sporulation_regulator_WhiA_C.
[Graphical view]
PfamiPF02650. HTH_WhiA. 1 hit.
PF10298. WhiA_N. 1 hit.
[Graphical view]
SUPFAMiSSF55608. SSF55608. 1 hit.
PROSITEiPS50819. INTEIN_ENDONUCLEASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q180P5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFSTETKNE LARVISGNEC CNIAELSALV KSGGSIQIVG YKKLNLKITT
60 70 80 90 100
ELNSIARKVF KLLKKNFNIN TTISVNKNQM LKRNNSYVLM VTSEMGSEML
110 120 130 140 150
LKKLGILEDK EGFFTINKIS ENLIKHEGCK RAFIRGAFLG GGSISDPEKN
160 170 180 190 200
YHMEFVTNNE EFADSLKELI NSLGFNSKIV ARKNNHVVYI KESEQISDLL
210 220 230 240 250
SIIGGHHALL SLQNTKIVKE MRNNVNRIVN CETANLSKTV NAAVRQVENI
260 270 280 290 300
KLIQETIGIS SLPENLQEIA KIRIEYEDMT LKELGEMLEP PIGKSGVNHR
310
LRKIEEIATD LKKKS
Length:315
Mass (Da):35,341
Last modified:May 26, 2009 - v2
Checksum:iF13097F1D8F1D226
GO

Sequence cautioni

The sequence CAJ70300.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ70300.1. Different initiation.
RefSeqiWP_003436252.1. NZ_CP010905.1.
WP_011861960.1. NC_009089.1.
YP_001089917.1. NC_009089.1.

Genome annotation databases

EnsemblBacteriaiCAJ70300; CAJ70300; CD630_33970.
GeneIDi4915774.
KEGGicdf:CD630_33970.
pdc:CDIF630_03702.
PATRICi19445353. VBICloDif38397_3560.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ70300.1. Different initiation.
RefSeqiWP_003436252.1. NZ_CP010905.1.
WP_011861960.1. NC_009089.1.
YP_001089917.1. NC_009089.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272563.CD3397.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ70300; CAJ70300; CD630_33970.
GeneIDi4915774.
KEGGicdf:CD630_33970.
pdc:CDIF630_03702.
PATRICi19445353. VBICloDif38397_3560.

Phylogenomic databases

eggNOGiENOG4105CIE. Bacteria.
COG1481. LUCA.
HOGENOMiHOG000040187.
KOiK09762.
OrthoDBiEOG68WR87.

Enzyme and pathway databases

BioCyciCDIF272563:GJFE-3651-MONOMER.

Family and domain databases

Gene3Di3.10.28.10. 1 hit.
HAMAPiMF_01420. HTH_type_WhiA.
InterProiIPR027434. Homing_endonucl.
IPR004042. Intein_endonuc.
IPR018478. Sporu_reg_WhiA_N_dom.
IPR003802. Sporulation_regulator_WhiA.
IPR023054. Sporulation_regulator_WhiA_C.
[Graphical view]
PfamiPF02650. HTH_WhiA. 1 hit.
PF10298. WhiA_N. 1 hit.
[Graphical view]
SUPFAMiSSF55608. SSF55608. 1 hit.
PROSITEiPS50819. INTEIN_ENDONUCLEASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 630.

Entry informationi

Entry nameiWHIA_PEPD6
AccessioniPrimary (citable) accession number: Q180P5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 26, 2009
Last sequence update: May 26, 2009
Last modified: July 6, 2016
This is version 69 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.