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Q180C9

- G6PI_PEPD6

UniProt

Q180C9 - G6PI_PEPD6

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Peptoclostridium difficile (strain 630) (Clostridium difficile)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (25 Jul 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei290 – 2901Proton donorUniRule annotation
    Active sitei311 – 3111UniRule annotation
    Active sitei425 – 4251UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciCDIF272563:GJFE-3529-MONOMER.
    UniPathwayiUPA00109; UER00181.
    UPA00138.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:CD630_32850
    OrganismiPeptoclostridium difficile (strain 630) (Clostridium difficile)
    Taxonomic identifieri272563 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium
    ProteomesiUP000001978: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 449449Glucose-6-phosphate isomerasePRO_1000013956Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272563.CD3285.

    Structurei

    3D structure databases

    ProteinModelPortaliQ180C9.
    SMRiQ180C9. Positions 4-448.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000100403.
    KOiK01810.
    OMAiQVIFIGN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q180C9-1 [UniParc]FASTAAdd to Basket

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    MGKINFDYSK ATEFFCQNEI DVMQPYVDVA HDMLHNKTGL GNTFLGWIDL    50
    PKNYDKEEFD RIKKSAEKIK SDSDVLLVIG IGGSYLGSRA AIDMVSHSFR 100
    NGLKKEQRKA PEVYFVGHNI SSTYIMDLLD IIEGKDISVN VISKSGTTTE 150
    PALAFRIFKD YLEKKYGKEE ARKRIYATTD ASKGALRQLA TEEGYETFVI 200
    PDDVGGRFSV LTAVGLLPIA AAGLDIDAMM KGANDAREAF QNPDLKSNDS 250
    YRYAVARTIL HRKGKDVELL VNYEPQLHYV SEWWKQLYGE SEGKENKGLF 300
    PASVDFSTDL HSMGQYIQDG KRLLFETVLN VENCKRNITI SSEEVDLDGL 350
    NYLAGKTVDF VNHKAFEGTL LAHTDGKVPN LVINIPQLDE YNFGYLVYFF 400
    EKACGISGYL LGVNPFDQPG VEAYKKNMFA LLGKPGYEKE KEELEKRLK 449
    Length:449
    Mass (Da):50,537
    Last modified:July 25, 2006 - v1
    Checksum:i15919E156688B036
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM180355 Genomic DNA. Translation: CAJ70182.1.
    RefSeqiYP_001089801.1. NC_009089.1.

    Genome annotation databases

    EnsemblBacteriaiCAJ70182; CAJ70182; CD630_32850.
    GeneIDi4913024.
    KEGGicdf:CD630_32850.
    PATRICi19445109. VBICloDif38397_3438.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM180355 Genomic DNA. Translation: CAJ70182.1 .
    RefSeqi YP_001089801.1. NC_009089.1.

    3D structure databases

    ProteinModelPortali Q180C9.
    SMRi Q180C9. Positions 4-448.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272563.CD3285.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAJ70182 ; CAJ70182 ; CD630_32850 .
    GeneIDi 4913024.
    KEGGi cdf:CD630_32850.
    PATRICi 19445109. VBICloDif38397_3438.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000100403.
    KOi K01810.
    OMAi QVIFIGN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    UPA00138 .
    BioCyci CDIF272563:GJFE-3529-MONOMER.

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 630.

    Entry informationi

    Entry nameiG6PI_PEPD6
    AccessioniPrimary (citable) accession number: Q180C9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: July 25, 2006
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3