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Protein
Submitted name:

Two-component response regulator

Gene

CD630_32650

Organism
Peptoclostridium difficile (strain 630) (Clostridium difficile)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi126 – 225OmpR/PhoB-typePROSITE-ProRule annotationAdd BLAST100

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation, Two-component regulatory systemSAAS annotation

Enzyme and pathway databases

BioCyciPDIF272563:G12WB-3432-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Two-component response regulatorImported
Gene namesi
Ordered Locus Names:CD630_32650Imported
OrganismiPeptoclostridium difficile (strain 630) (Clostridium difficile)Imported
Taxonomic identifieri272563 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaeClostridioides
Proteomesi
  • UP000001978 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

STRINGi272563.CD3265.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2QZJX-ray2.89A/B/C/D/E/F2-126[»]
ProteinModelPortaliQ180B0.
SMRiQ180B0.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ180B0.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 117Response regulatoryInterPro annotationAdd BLAST114
Domaini126 – 225OmpR/PhoB-type DNA-bindingInterPro annotationAdd BLAST100

Phylogenomic databases

eggNOGiCOG0745. LUCA.
HOGENOMiHOG000034819.
OMAiYHTELIY.

Family and domain databases

CDDicd00383. trans_reg_C. 1 hit.
Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR011006. CheY-like_superfamily.
IPR001867. OmpR/PhoB-type_DNA-bd.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00072. Response_reg. 1 hit.
PF00486. Trans_reg_C. 1 hit.
SMARTiView protein in SMART
SM00448. REC. 1 hit.
SM00862. Trans_reg_C. 1 hit.
SUPFAMiSSF46894. SSF46894. 1 hit.
SSF52172. SSF52172. 1 hit.
PROSITEiView protein in PROSITE
PS51755. OMPR_PHOB. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.

Sequencei

Sequence statusi: Complete.

Q180B0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQTKILIIDG DKDNCQKLKG FLEEKGISID LAYNCEEAIG KIFSNKYDLI
60 70 80 90 100
FLEIILSDGD GWTLCKKIRN VTTCPIVYMT YINEDQSILN ALNSGGDDYL
110 120 130 140 150
IKPLNLEILY AKVKAILRRM NSYVNNNENN TKLEEYNRTS GVIKLEDKII
160 170 180 190 200
KLTPTENKLL NFFIENPEKT LTTKEIYEHV WMNEYLEDNY SVVVAVNGLR
210 220
KKIEKDYKNP QKIITIRGAG YYFNKE
Length:226
Mass (Da):26,204
Last modified:July 25, 2006 - v1
Checksum:iB7FA915E8674F0BA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180355 Genomic DNA. Translation: CAJ70162.1.
RefSeqiWP_003432361.1. NC_009089.1.
YP_001089781.1. NC_009089.1.

Genome annotation databases

EnsemblBacteriaiCAJ70162; CAJ70162; CD630_32650.
GeneIDi31354886.
4915689.
KEGGicdf:CD630_32650.
pdc:CDIF630_03564.
PATRICifig|272563.120.peg.3450.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ180B0_PEPD6
AccessioniPrimary (citable) accession number: Q180B0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: July 5, 2017
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported