Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q18081

- UGT48_CAEEL

UniProt

Q18081 - UGT48_CAEEL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Putative UDP-glucuronosyltransferase ugt-48

Gene

ugt-48

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.

GO - Molecular functioni

  1. glucuronosyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative UDP-glucuronosyltransferase ugt-48 (EC:2.4.1.17)
Short name:
UDPGT 48
Gene namesi
Name:ugt-48
Synonyms:ugt15
ORF Names:C18C4.3
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome V

Organism-specific databases

WormBaseiC18C4.3; CE38487; WBGene00015965; ugt-48.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717Sequence AnalysisAdd
BLAST
Chaini18 – 526509Putative UDP-glucuronosyltransferase ugt-48PRO_0000036054Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi58 – 581N-linked (GlcNAc...)1 Publication
Glycosylationi305 – 3051N-linked (GlcNAc...)Sequence Analysis
Glycosylationi513 – 5131N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ18081.

Interactioni

Protein-protein interaction databases

BioGridi43989. 2 interactions.
MINTiMINT-1047334.
STRINGi6239.C18C4.3.1.

Structurei

3D structure databases

ProteinModelPortaliQ18081.
SMRiQ18081. Positions 227-449.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei489 – 50921HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG320140.
GeneTreeiENSGT00760000119404.
HOGENOMiHOG000018977.
InParanoidiQ18081.
KOiK00699.
OMAiHEVVNFE.
OrthoDBiEOG7FJH06.
PhylomeDBiQ18081.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q18081-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLLRILTFLA VCQVTTSHKI LMFSPTASKS HMISQGRIAD ELANAGHEVV
60 70 80 90 100
NFEPDFLNLT DKFVPCKKCR RWPVTGLNNY KFKKIQNGLS GDVFQQSSIW
110 120 130 140 150
SKIFNTDSDP YQDEYTNMCE EMVTNKELIE KLKKEKFDAY FGEQIHLCGM
160 170 180 190 200
GLAHLIGIKH RFWIASCTMS VSMRDSLGIP TPSSLIPFMS TLDATPAPFW
210 220 230 240 250
QRAKNFVLQM AHIRDEYRDV VLTNDMFKKN FGSDFPCVEF LAKTSDLIFV
260 270 280 290 300
STDELLEIQA PTLSNVVHIG GLGLSSEGGG LDEKFVKIME KGKGVILFSL
310 320 330 340 350
GTIANTTNLP PTIMENLMKI TQKFKDYEFI IKVDKFDRRS FDLAEGLSNV
360 370 380 390 400
LVVDWVPQTA VLAHPRLKAF ITHAGYNSLM ESAYAGVPVI LIPFMFDQPR
410 420 430 440 450
NGRSVERKGW GILRDRFQLI KDPDAIEGAI KEILVNPTYQ EKANRLKKLM
460 470 480 490 500
RSKPQSASER LVKMTNWVLE NDGVEELQYE GKHMDFFTFY NLDIIITAAS
510 520
IPVLIFIVLR ISNISIITSS PKNKKD
Length:526
Mass (Da):59,627
Last modified:March 21, 2006 - v3
Checksum:iC291099EE08F9FB5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FO080608 Genomic DNA. Translation: CCD65106.1.
RefSeqiNP_504464.2. NM_072063.5.
UniGeneiCel.23456.

Genome annotation databases

EnsemblMetazoaiC18C4.3.1; C18C4.3.1; WBGene00015965.
C18C4.3.2; C18C4.3.2; WBGene00015965.
GeneIDi178940.
KEGGicel:CELE_C18C4.3.
UCSCiC18C4.3.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FO080608 Genomic DNA. Translation: CCD65106.1 .
RefSeqi NP_504464.2. NM_072063.5.
UniGenei Cel.23456.

3D structure databases

ProteinModelPortali Q18081.
SMRi Q18081. Positions 227-449.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 43989. 2 interactions.
MINTi MINT-1047334.
STRINGi 6239.C18C4.3.1.

Protein family/group databases

CAZyi GT1. Glycosyltransferase Family 1.

Proteomic databases

PaxDbi Q18081.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai C18C4.3.1 ; C18C4.3.1 ; WBGene00015965 .
C18C4.3.2 ; C18C4.3.2 ; WBGene00015965 .
GeneIDi 178940.
KEGGi cel:CELE_C18C4.3.
UCSCi C18C4.3.1. c. elegans.

Organism-specific databases

CTDi 178940.
WormBasei C18C4.3 ; CE38487 ; WBGene00015965 ; ugt-48.

Phylogenomic databases

eggNOGi NOG320140.
GeneTreei ENSGT00760000119404.
HOGENOMi HOG000018977.
InParanoidi Q18081.
KOi K00699.
OMAi HEVVNFE.
OrthoDBi EOG7FJH06.
PhylomeDBi Q18081.

Miscellaneous databases

NextBioi 903208.

Family and domain databases

InterProi IPR002213. UDP_glucos_trans.
[Graphical view ]
PANTHERi PTHR11926. PTHR11926. 1 hit.
Pfami PF00201. UDPGT. 1 hit.
[Graphical view ]
PROSITEi PS00375. UDPGT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.
  2. "Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis elegans and suggests an atypical translocation mechanism for integral membrane proteins."
    Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T., Taoka M., Takahashi N., Isobe T.
    Mol. Cell. Proteomics 6:2100-2109(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-58, IDENTIFICATION BY MASS SPECTROMETRY.
    Strain: Bristol N2.

Entry informationi

Entry nameiUGT48_CAEEL
AccessioniPrimary (citable) accession number: Q18081
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: March 21, 2006
Last modified: October 29, 2014
This is version 97 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3