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Protein

Putative UDP-glucuronosyltransferase ugt-48

Gene

ugt-48

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Ligandi

Calmodulin-binding

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative UDP-glucuronosyltransferase ugt-48 (EC:2.4.1.17)
Short name:
UDPGT 48
Gene namesi
Name:ugt-48
Synonyms:ugt15
ORF Names:C18C4.3
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiC18C4.3; CE38487; WBGene00015965; ugt-48.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei489 – 509HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_000003605418 – 526Putative UDP-glucuronosyltransferase ugt-48Add BLAST509

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi58N-linked (GlcNAc...)1 Publication1
Glycosylationi305N-linked (GlcNAc...)Sequence analysis1
Glycosylationi513N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

EPDiQ18081.
PaxDbiQ18081.
PeptideAtlasiQ18081.
PRIDEiQ18081.

Expressioni

Gene expression databases

BgeeiWBGene00015965.

Interactioni

Subunit structurei

Interacts with cmd-1 in the presence of Ca2+.1 Publication

Protein-protein interaction databases

BioGridi43989. 2 interactors.
MINTiMINT-1047334.
STRINGi6239.C18C4.3.1.

Structurei

3D structure databases

ProteinModelPortaliQ18081.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1192. Eukaryota.
COG1819. LUCA.
GeneTreeiENSGT00840000130042.
HOGENOMiHOG000018977.
InParanoidiQ18081.
KOiK00699.
OMAiRWINTGE.
OrthoDBiEOG091G0720.
PhylomeDBiQ18081.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q18081-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLRILTFLA VCQVTTSHKI LMFSPTASKS HMISQGRIAD ELANAGHEVV
60 70 80 90 100
NFEPDFLNLT DKFVPCKKCR RWPVTGLNNY KFKKIQNGLS GDVFQQSSIW
110 120 130 140 150
SKIFNTDSDP YQDEYTNMCE EMVTNKELIE KLKKEKFDAY FGEQIHLCGM
160 170 180 190 200
GLAHLIGIKH RFWIASCTMS VSMRDSLGIP TPSSLIPFMS TLDATPAPFW
210 220 230 240 250
QRAKNFVLQM AHIRDEYRDV VLTNDMFKKN FGSDFPCVEF LAKTSDLIFV
260 270 280 290 300
STDELLEIQA PTLSNVVHIG GLGLSSEGGG LDEKFVKIME KGKGVILFSL
310 320 330 340 350
GTIANTTNLP PTIMENLMKI TQKFKDYEFI IKVDKFDRRS FDLAEGLSNV
360 370 380 390 400
LVVDWVPQTA VLAHPRLKAF ITHAGYNSLM ESAYAGVPVI LIPFMFDQPR
410 420 430 440 450
NGRSVERKGW GILRDRFQLI KDPDAIEGAI KEILVNPTYQ EKANRLKKLM
460 470 480 490 500
RSKPQSASER LVKMTNWVLE NDGVEELQYE GKHMDFFTFY NLDIIITAAS
510 520
IPVLIFIVLR ISNISIITSS PKNKKD
Length:526
Mass (Da):59,627
Last modified:March 21, 2006 - v3
Checksum:iC291099EE08F9FB5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080608 Genomic DNA. Translation: CCD65106.1.
RefSeqiNP_504464.2. NM_072063.5.
UniGeneiCel.23456.

Genome annotation databases

EnsemblMetazoaiC18C4.3.1; C18C4.3.1; WBGene00015965.
C18C4.3.2; C18C4.3.2; WBGene00015965.
GeneIDi178940.
KEGGicel:CELE_C18C4.3.
UCSCiC18C4.3.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080608 Genomic DNA. Translation: CCD65106.1.
RefSeqiNP_504464.2. NM_072063.5.
UniGeneiCel.23456.

3D structure databases

ProteinModelPortaliQ18081.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi43989. 2 interactors.
MINTiMINT-1047334.
STRINGi6239.C18C4.3.1.

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Proteomic databases

EPDiQ18081.
PaxDbiQ18081.
PeptideAtlasiQ18081.
PRIDEiQ18081.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC18C4.3.1; C18C4.3.1; WBGene00015965.
C18C4.3.2; C18C4.3.2; WBGene00015965.
GeneIDi178940.
KEGGicel:CELE_C18C4.3.
UCSCiC18C4.3.1. c. elegans.

Organism-specific databases

CTDi178940.
WormBaseiC18C4.3; CE38487; WBGene00015965; ugt-48.

Phylogenomic databases

eggNOGiKOG1192. Eukaryota.
COG1819. LUCA.
GeneTreeiENSGT00840000130042.
HOGENOMiHOG000018977.
InParanoidiQ18081.
KOiK00699.
OMAiRWINTGE.
OrthoDBiEOG091G0720.
PhylomeDBiQ18081.

Miscellaneous databases

PROiQ18081.

Gene expression databases

BgeeiWBGene00015965.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiUGT48_CAEEL
AccessioniPrimary (citable) accession number: Q18081
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: March 21, 2006
Last modified: November 2, 2016
This is version 115 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.