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Protein
Submitted name:

ASpartyl Protease

Gene

hrg-7

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei90PROSITE-ProRule annotation1
Active sitei318PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAspartyl proteasePROSITE-ProRule annotation, Hydrolase, Protease

Protein family/group databases

MEROPSiA01.A76.

Names & Taxonomyi

Protein namesi
Submitted name:
ASpartyl ProteaseImported
Gene namesi
Name:hrg-7Imported
Synonyms:asp-10Imported
ORF Names:C15C8.3Imported, CELE_C15C8.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiC15C8.3a; CE05287; WBGene00007605; hrg-7.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_500418673817 – 428Sequence analysisAdd BLAST412

Proteomic databases

EPDiQ18020.
PaxDbiQ18020.
PeptideAtlasiQ18020.

Expressioni

Gene expression databases

BgeeiWBGene00007605.
ExpressionAtlasiQ18020. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiQ18020. 1 interactor.
STRINGi6239.C15C8.3a.2.

Structurei

3D structure databases

ProteinModelPortaliQ18020.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini72 – 425Peptidase A1InterPro annotationAdd BLAST354

Sequence similaritiesi

Belongs to the peptidase A1 family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1339. Eukaryota.
ENOG410XNV7. LUCA.
GeneTreeiENSGT00760000118929.
HOGENOMiHOG000197681.
InParanoidiQ18020.
OMAiFYPAWML.
OrthoDBiEOG091G07VO.
PhylomeDBiQ18020.

Family and domain databases

CDDicd05471. pepsin_like. 1 hit.
Gene3Di2.40.70.10. 2 hits.
InterProiView protein in InterPro
IPR001461. Aspartic_peptidase_A1.
IPR034164. Pepsin-like_dom.
IPR033121. PEPTIDASE_A1.
IPR021109. Peptidase_aspartic_dom_sf.
PANTHERiPTHR13683. PTHR13683. 1 hit.
PfamiView protein in Pfam
PF00026. Asp. 1 hit.
PRINTSiPR00792. PEPSIN.
SUPFAMiSSF50630. SSF50630. 2 hits.
PROSITEiView protein in PROSITE
PS51767. PEPTIDASE_A1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q18020-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTFIALLAL LTVVSAEVHQ FNIGYRPNMR QRMNAKGKLA EYEKERNELL
60 70 80 90 100
SKKSLQLASS SSPVIDYEDM AYMVQISLGS PAQNFVLFID SGSSNLWVPD
110 120 130 140 150
ITCAGGKDAT CGSYCKSTPY DACLTFCQEE CCTKTVEGVK VLSTTDACQS
160 170 180 190 200
KHRFNSSLSS SYVTNGQKFD MTYNTGEVKG FFGVDTFCFT NTSVCATGQV
210 220 230 240 250
FGQATTIGEA FAKQPEDGII GLGWPALAVN QQTPPLFNLM NQGKLDQPYF
260 270 280 290 300
VVYLANIGPT SQINGGAFTV GGLDTTHCSS NVDWVPLSTQ TFWQFKLGGV
310 320 330 340 350
SSGSYSQAPN SGWQAAADTA ASFIGAPKSV VTSLAKAVGA TYVPLTGAFF
360 370 380 390 400
MDCDAVVPDI VFTINGKTYN MPSTSFVVSA GPGPCMFAFY ELTAGGFYPA
410 420
WMLGPPFMRA YCHVHDMKSG RLGLAKVL
Length:428
Mass (Da):45,993
Last modified:November 1, 1996 - v1
Checksum:i2E1378E9F59CD14E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CAA99777.1.
PIRiT19309.
RefSeqiNP_001256448.1. NM_001269519.1.
UniGeneiCel.36122.

Genome annotation databases

EnsemblMetazoaiC15C8.3a; C15C8.3a; WBGene00007605.
GeneIDi182635.
KEGGicel:CELE_C15C8.3.
UCSCiC15C8.3. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ18020_CAEEL
AccessioniPrimary (citable) accession number: Q18020
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 22, 2017
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported