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Q17ZY4 (PRAC_CLOD6) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Proline racemase

EC=5.1.1.4
Gene names
Ordered Locus Names:CD630_32370
OrganismClostridium difficile (strain 630) [Complete proteome] [HAMAP]
Taxonomic identifier272563 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceae

Protein attributes

Sequence length335 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Strong B-cell mitogen. Plays an important role in the regulation of intra- and extracellular amino acid pools, allowing the bacterium to profit from host precursors and enzymatic pathways By similarity.

Catalytic activity

L-proline = D-proline.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the proline racemase family.

Ontologies

Keywords
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionproline racemase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 335335Proline racemase
PRO_0000354023

Sites

Active site911Proton acceptor By similarity
Active site2551Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q17ZY4 [UniParc].

Last modified July 25, 2006. Version 1.
Checksum: C1C7BD9E6E3FAB86

FASTA33536,221
        10         20         30         40         50         60 
MKFSRSIQAI DSHTAGEATR IVVGGIPNIK GNSMPEKKEY LEENLDYLRT AIMLEPRGHN 

        70         80         90        100        110        120 
DMFGSVMTQP CCPDADFGII FMDGGGYLNM CGHGTIGAMT AAIETGVVPA VEPVTHVVME 

       130        140        150        160        170        180 
APAGIIRGDV TVVDGKAKEV SFLNVPAFLY KEGVEVDLPG VGTVKFDISF GGSFFAIIHA 

       190        200        210        220        230        240 
SQLGLKIEPQ NAGKLTELAM KLRDIINEKI EIQHPTLAHI KTVDLVEIYD EPTHPEATYK 

       250        260        270        280        290        300 
NVVIFGQGQV DRSPCGTGTS AKLATLHAKG ELKVGEKFVY ESILGTLFKG EIVEETKVAD 

       310        320        330 
FNAVVPKITG SAYITGFNHF VIDEEDPLKH GFILK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM180355 Genomic DNA. Translation: CAJ70135.1.
RefSeqYP_001089754.1. NC_009089.1.

3D structure databases

ProteinModelPortalQ17ZY4.
SMRQ17ZY4. Positions 3-335.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272563.CD3237.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ70135; CAJ70135; CD630_32370.
GeneID4916393.
KEGGcdf:CD630_32370.
PATRIC19445013. VBICloDif38397_3390.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3938.
HOGENOMHOG000084336.
KOK01777.
OMAFGGNFYA.
OrthoDBEOG6SNDV3.
ProtClustDBPRK13969.

Enzyme and pathway databases

BioCycCDIF272563:GJFE-3480-MONOMER.
BRENDA5.1.1.4. 1473.

Family and domain databases

InterProIPR008794. Pro_racemase_fam.
[Graphical view]
PfamPF05544. Pro_racemase. 1 hit.
[Graphical view]
PIRSFPIRSF029792. Pro_racemase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePRAC_CLOD6
AccessionPrimary (citable) accession number: Q17ZY4
Entry history
Integrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: July 25, 2006
Last modified: April 16, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families