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Q17YK6 (GLK_HELAH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucokinase

EC=2.7.1.2
Alternative name(s):
Glucose kinase
Gene names
Name:glk
Ordered Locus Names:Hac_0439
OrganismHelicobacter acinonychis (strain Sheeba) [Complete proteome] [HAMAP]
Taxonomic identifier382638 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length336 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP-Rule MF_00524

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00524.

Sequence similarities

Belongs to the bacterial glucokinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glucokinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 336336Glucokinase HAMAP-Rule MF_00524
PRO_1000050969

Regions

Nucleotide binding12 – 176ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q17YK6 [UniParc].

Last modified July 25, 2006. Version 1.
Checksum: B356F4AE0AA8DF75

FASTA33636,737
        10         20         30         40         50         60 
MPKTETYPRL LADIGGTNAR FGLEVASRQI ECIEVLRCED FESLSDAVRF YLSKHQESLK 

        70         80         90        100        110        120 
LCPIYGSFAV ATPIMGDFVQ MTNNHWTFSI ETTRQCLGLE RLLVVNDFVA QAFAISTMQE 

       130        140        150        160        170        180 
NDLAQVGGIK CEINAPKAVL GPGTGLGVST LIQNSDGSLK VLPGEGGHVS FAPFDDLEIL 

       190        200        210        220        230        240 
VWQYARSKFN HVSAERFLSG SGLVLIYEAL SKRKSMEKVA KLSKAELTPQ IISERALNGD 

       250        260        270        280        290        300 
YPLCRLTLDT FCSMLGTLAA DVALTLGARG GVYLCGGIIP RFIDYFKTSP FRARFETKGR 

       310        320        330 
MGAFLASIPV HVVLKKTPGL DGVGIALENY LLHDKI 

« Hide

References

[1]"Who ate whom? Adaptive Helicobacter genomic changes that accompanied a host jump from early humans to large felines."
Eppinger M., Baar C., Linz B., Raddatz G., Lanz C., Keller H., Morelli G., Gressmann H., Achtman M., Schuster S.C.
PLoS Genet. 2:1097-1110(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sheeba.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM260522 Genomic DNA. Translation: CAJ99270.1.
RefSeqYP_664269.1. NC_008229.1.

3D structure databases

ProteinModelPortalQ17YK6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING382638.Hac_0439.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ99270; CAJ99270; Hac_0439.
GeneID4177766.
KEGGhac:Hac_0439.
PATRIC20584815. VBIHelAci71660_0429.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0837.
HOGENOMHOG000274469.
KOK00845.
OMADWVEMTN.
OrthoDBEOG64BQ47.

Enzyme and pathway databases

BioCycHACI382638:GJAU-416-MONOMER.

Family and domain databases

HAMAPMF_00524. Glucokinase.
InterProIPR003836. Glucokinase.
[Graphical view]
PfamPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00749. glk. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLK_HELAH
AccessionPrimary (citable) accession number: Q17YK6
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 25, 2006
Last modified: June 11, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families