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Q17WB2 (Q17WB2_HELAH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyrroline-5-carboxylate reductase RuleBase RU003903
EC=1.5.1.2 RuleBase RU003903
Gene names
Name:proC EMBL CAK00064.1
Ordered Locus Names:Hac_1325
OrganismHelicobacter acinonychis (strain Sheeba) [Complete proteome] [HAMAP]
Taxonomic identifier382638 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter

Protein attributes

Sequence length257 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-proline + NAD(P)+ = 1-pyrroline-5-carboxylate + NAD(P)H. RuleBase RU003903

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1. RuleBase RU003903

Sequence similarities

Belongs to the pyrroline-5-carboxylate reductase family. RuleBase RU003903

Sequences

Sequence LengthMass (Da)Tools
Q17WB2 [UniParc].

Last modified July 25, 2006. Version 1.
Checksum: 8D8871EFFA8BEC75

FASTA25727,999
        10         20         30         40         50         60 
METLQLVGYG NMAQAILEGS HEILSKHFIL EITGRNPEKI APFLKEKNIQ AQIVSYPNAI 

        70         80         90        100        110        120 
DIHQKFVFLL FKPYNLKSFN YQGQAKSVLS ALAGVGFEAL KGAIDSLHYL KCMPNIASKF 

       130        140        150        160        170        180 
ALSSTAVCEK SVVPLISQKA LSIIESFGGC VRVGSEEQVD SSAATNGSVL AFLSLVASSL 

       190        200        210        220        230        240 
KDAGIREGLN ARDSLELVKM SFKGFAKLLE QERPEMITEQ ICTPKGVTIE GLSVLEKRGV 

       250 
RGAFMEACHE SVKKMRP

« Hide

References

[1]"Who ate whom? Adaptive Helicobacter genomic changes that accompanied a host jump from early humans to large felines."
Eppinger M., Baar C., Linz B., Raddatz G., Lanz C., Keller H., Morelli G., Gressmann H., Achtman M., Schuster S.C.
PLoS Genet. 2:1097-1110(2006) [PubMed: 16789826] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM260522 Genomic DNA. Translation: CAK00064.1.
RefSeqYP_665063.1. NC_008229.1.

3D structure databases

ProteinModelPortalQ17WB2.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ17WB2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4176563.
GenomeReviewsGene locus Hac_1325 in contig AM260522_GR.
KEGGhac:Hac_1325.
NMPDRfig|382638.8.peg.1285.
PATRIC20586494. VBIHelAci71660_1252.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0345.
HOGENOMHBG726602.
OMAACHESVK.
ProtClustDBPRK11880.

Family and domain databases

InterProIPR008927. 6-PGluconate_DH_C-like.
IPR016040. NAD(P)-bd_dom.
IPR004455. NADP_OxRdtase_F420.
IPR000304. Pyrroline-COOH_reductase.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00286.
PANTHERPTHR11645. P5CR. 1 hit.
PfamPF03807. F420_oxidored. 1 hit.
[Graphical view]
PIRSFPIRSF000193. Pyrrol-5-carb_rd. 1 hit.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMsTIGR00112. ProC. 1 hit.
PROSITEPS00521. P5CR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ17WB2_HELAH
AccessionPrimary (citable) accession number: Q17WB2
Entry history
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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