Q17VY8 (Q17VY8_HELAH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cystathionine gamma-synthase EMBL CAK00188.1
EC=2.5.1.48 EMBL CAK00188.1

Gene names

Name:	metB EMBL CAK00188.1
Ordered Locus Names:	Hac_1464

Organism

Helicobacter acinonychis (strain Sheeba) [Complete proteome] [HAMAP]

Taxonomic identifier

382638 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter

Protein attributes

Sequence length	380 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU004507
Sequence similarities	Belongs to the trans-sulfuration enzymes family. RuleBase RU004079

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU004507
Molecular function	Transferase EMBL CAK00188.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular amino acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	cystathionine gamma-synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q17VY8 [UniParc]. Last modified July 25, 2006. Version 1. Checksum: FCC5AF77E67FC69A	FASTA	380	41,140
	10 20 30 40 50 60 MHMQTKLIHG GISEDATTGA VSVPIYQTST YRQDAIGRPK GYEYSRSGNP TRFALEELIA 70 80 90 100 110 120 DLEGGVKGFA FASGLAGIHA VFSLFQSGDH VLLGDDVYGG TFRLFDKVLS KNGLSCTIIE 130 140 150 160 170 180 TSDIPQIKKA IKPNTKALYL ESPSNPLLKI TDLKQCASLA KAHGLLTIVD NTFATPYYQN 190 200 210 220 230 240 PLLLGADIVV HSGTKYLGGH SDVVAGLVTT NNEALAQEIA FFQNAIGGVL GPQDSWLLQR 250 260 270 280 290 300 GIKTLGLRME AHQKNALCVA EFLEKHPKVE RVYYPGLPTH LNHDLAKAQM RGFSGMLSFT 310 320 330 340 350 360 LKNDNEATPF VENLKLFILG ESLGGVESLV GIPVLMTHAC IPKVQREAAG IRDGLVRLSV 370 380 GIEHEKDLLE DLEQAFAKLG

References

[1]

"Who ate whom? Adaptive Helicobacter genomic changes that accompanied a host jump from early humans to large felines." Eppinger M., Baar C., Linz B., Raddatz G., Lanz C., Keller H., Morelli G., Gressmann H., Achtman M., Schuster S.C. PLoS Genet. 2:1097-1110(2006) [PubMed: 16789826] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM260522 Genomic DNA. Translation: CAK00188.1.
RefSeq	YP_665187.1. NC_008229.1.
3D structure databases
ProteinModelPortal	Q17VY8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q17VY8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4176761.
GenomeReviews	Gene locus Hac_1464 in contig AM260522_GR.
KEGG	hac:Hac_1464.
NMPDR	fig|382638.8.peg.1418.
PATRIC	20586762. VBIHelAci71660_1385.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0626.
HOGENOM	HBG754729.
OMA	NQYEYSR.
PhylomeDB	Q17VY8.
ProtClustDB	PRK06176.
Family and domain databases
InterPro	IPR000277. Cys/Met-Metab_PyrdxlP-dep_enz. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K01760.
PANTHER	PTHR11808. Cys_Met_Meta_PP. 1 hit.
Pfam	PF01053. Cys_Met_Meta_PP. 1 hit. [Graphical view]
PIRSF	PIRSF001434. CGS. 1 hit.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITE	PS00868. CYS_MET_METAB_PP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q17VY8_HELAH

Accession

Primary (citable) accession number: Q17VY8

Entry history

Integrated into UniProtKB/TrEMBL:	July 25, 2006
Last sequence update:	July 25, 2006
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)