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Protein

Olfactory receptor

Gene

OR7A5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer
Biological processOlfactionUniRule annotationSAAS annotation, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:OR7A5Imported
ORF Names:hCG_2000909Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei23 – 47HelicalUniRule annotationAdd BLAST25
Transmembranei59 – 79HelicalUniRule annotationAdd BLAST21
Transmembranei91 – 120HelicalUniRule annotationAdd BLAST30
Transmembranei140 – 158HelicalUniRule annotationAdd BLAST19
Transmembranei197 – 219HelicalUniRule annotationAdd BLAST23
Transmembranei240 – 260HelicalUniRule annotationAdd BLAST21
Transmembranei272 – 292HelicalUniRule annotationAdd BLAST21

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 290G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST250

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IVB1. Eukaryota.
ENOG410YBQN. LUCA.
HOVERGENiHBG017625.

Family and domain databases

InterProiView protein in InterPro
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
PfamiView protein in Pfam
PF13853. 7tm_4. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q17RS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METGNQTHAQ EFLLLGFSAT SEIQFILFGL FLSMYLVTFT GNLLIILAIC
60 70 80 90 100
SDSHLHTPMY FFLSNLSFAD LCFTSTTVPK MLLNILTQNK FITYAGCLSQ
110 120 130 140 150
IFFFTSFGCL DNLLLTVMAY DRFVAICHPL HYTVIMNPQL CGLLVLGSWC
160 170 180 190 200
ISVMGSLLET LTVLRLSFCT KMEIPHFFCD LLEVLKLACS DTFINNVVIY
210 220 230 240 250
FATGVLGVIS FTGIFFSYYK IVFSILRISS AGRKHKAFST CGSHLSVVTL
260 270 280 290 300
FYGTGFGVYL SSAATPSSRT SLVASVMYTM VTPMLNPFIY SLRNTDMKRA
310 320
LGRLLSRATF FNGDITAGLS
Length:320
Mass (Da):35,532
Last modified:July 25, 2006 - v1
Checksum:i782A6D2608DC39A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC117212 mRNA. Translation: AAI17213.1.
CH471106 Genomic DNA. Translation: EAW84449.1.
UniGeneiHs.466053.

Similar proteinsi

Entry informationi

Entry nameiQ17RS1_HUMAN
AccessioniPrimary (citable) accession number: Q17RS1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: November 22, 2017
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.