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Protein

RUN domain-containing protein 3A

Gene

RUNDC3A

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May act as an effector of RAP2A in neuronal cells.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
RUN domain-containing protein 3A
Gene namesi
Name:RUNDC3A
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 19

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 441441RUN domain-containing protein 3APRO_0000324154Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei210 – 2101PhosphothreonineBy similarity
Modified residuei227 – 2271PhosphoserineBy similarity
Modified residuei411 – 4111PhosphoserineBy similarity
Modified residuei414 – 4141PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ17QK1.
PRIDEiQ17QK1.

Interactioni

Subunit structurei

Interacts with the GTP-bound form of RAP2A.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000002119.

Structurei

3D structure databases

ProteinModelPortaliQ17QK1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini52 – 184133RUNPROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 293293Interaction with RAP2ABy similarityAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili262 – 31756Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the RUNDC3 family.Curated
Contains 1 RUN domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG4381. Eukaryota.
ENOG410XRAX. LUCA.
GeneTreeiENSGT00550000074558.
HOGENOMiHOG000143407.
HOVERGENiHBG052747.
InParanoidiQ17QK1.
OMAiKSNECLV.
OrthoDBiEOG70CR6K.
TreeFamiTF323904.

Family and domain databases

InterProiIPR004012. Run_dom.
[Graphical view]
PfamiPF02759. RUN. 1 hit.
[Graphical view]
SMARTiSM00593. RUN. 1 hit.
[Graphical view]
PROSITEiPS50826. RUN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q17QK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEASFVQTTM ALGLSSKKAS SRNVAVERRN LITVCRFSVK TLLEKYTTEP
60 70 80 90 100
IDDSSEEFVN FAAILEQILS HRFKGPVSWF SSDGQRGFWD YIRLACSKVP
110 120 130 140 150
NNCVSSIENM ENISTARAKG RAWIRVALME KRMSEYITTA LRDTRTTRRF
160 170 180 190 200
YDSGAIMMRE EATVLTGMLI GLSAIDFSFC LKGEVLDGKT PVVIDYTPYL
210 220 230 240 250
KFTQSYDYLT DEEERHSAES STSEDNSPEH PYLPLVTDED SWYSKWHKME
260 270 280 290 300
QKFRIVYAQK GYLEELVRLR ESQLKDLEAE NRRLQLQLEE AAAQNQREKR
310 320 330 340 350
ELEGVILELQ EQLTGLIPGD HAPLAQGSKD LTTRLVNQWP SLGTLSGAEG
360 370 380 390 400
ANNPKLYRRH SFMSTEPLSA EASLSSDSQR LGEGKRDEEP WGPIGKDPTP
410 420 430 440
SMLGLCGSLA SIPSCKSLAS FKSNECLVSD SPEGSPALSP S
Length:441
Mass (Da):49,462
Last modified:July 25, 2006 - v1
Checksum:iF9AAD1D27ABC1968
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC118315 mRNA. Translation: AAI18316.1.
RefSeqiNP_001069790.1. NM_001076322.1.
UniGeneiBt.34847.

Genome annotation databases

EnsembliENSBTAT00000002119; ENSBTAP00000002119; ENSBTAG00000001615.
GeneIDi614322.
KEGGibta:614322.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC118315 mRNA. Translation: AAI18316.1.
RefSeqiNP_001069790.1. NM_001076322.1.
UniGeneiBt.34847.

3D structure databases

ProteinModelPortaliQ17QK1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000002119.

Proteomic databases

PaxDbiQ17QK1.
PRIDEiQ17QK1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000002119; ENSBTAP00000002119; ENSBTAG00000001615.
GeneIDi614322.
KEGGibta:614322.

Organism-specific databases

CTDi10900.

Phylogenomic databases

eggNOGiKOG4381. Eukaryota.
ENOG410XRAX. LUCA.
GeneTreeiENSGT00550000074558.
HOGENOMiHOG000143407.
HOVERGENiHBG052747.
InParanoidiQ17QK1.
OMAiKSNECLV.
OrthoDBiEOG70CR6K.
TreeFamiTF323904.

Family and domain databases

InterProiIPR004012. Run_dom.
[Graphical view]
PfamiPF02759. RUN. 1 hit.
[Graphical view]
SMARTiSM00593. RUN. 1 hit.
[Graphical view]
PROSITEiPS50826. RUN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Brain cortex.

Entry informationi

Entry nameiRUN3A_BOVIN
AccessioniPrimary (citable) accession number: Q17QK1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: July 25, 2006
Last modified: June 8, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.