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Protein

RUN domain-containing protein 3A

Gene

RUNDC3A

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May act as an effector of RAP2A in neuronal cells.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
RUN domain-containing protein 3A
Gene namesi
Name:RUNDC3A
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 19

Organism-specific databases

VGNCiVGNC:34218 RUNDC3A

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003241541 – 441RUN domain-containing protein 3AAdd BLAST441

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei210PhosphothreonineBy similarity1
Modified residuei227PhosphoserineBy similarity1
Modified residuei411PhosphoserineBy similarity1
Modified residuei414PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ17QK1
PRIDEiQ17QK1

Expressioni

Gene expression databases

BgeeiENSBTAG00000001615

Interactioni

Subunit structurei

Interacts with the GTP-bound form of RAP2A.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ17QK1
SMRiQ17QK1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini52 – 184RUNPROSITE-ProRule annotationAdd BLAST133

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 293Interaction with RAP2ABy similarityAdd BLAST293

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili262 – 317Sequence analysisAdd BLAST56

Sequence similaritiesi

Belongs to the RUNDC3 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG4381 Eukaryota
ENOG410XRAX LUCA
GeneTreeiENSGT00550000074558
HOGENOMiHOG000143407
HOVERGENiHBG052747
InParanoidiQ17QK1
OMAiTRDEEPW
OrthoDBiEOG091G06Y5
TreeFamiTF323904

Family and domain databases

InterProiView protein in InterPro
IPR004012 Run_dom
IPR037213 Run_dom_sf
PfamiView protein in Pfam
PF02759 RUN, 1 hit
SMARTiView protein in SMART
SM00593 RUN, 1 hit
SUPFAMiSSF140741 SSF140741, 1 hit
PROSITEiView protein in PROSITE
PS50826 RUN, 1 hit

Sequencei

Sequence statusi: Complete.

Q17QK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEASFVQTTM ALGLSSKKAS SRNVAVERRN LITVCRFSVK TLLEKYTTEP
60 70 80 90 100
IDDSSEEFVN FAAILEQILS HRFKGPVSWF SSDGQRGFWD YIRLACSKVP
110 120 130 140 150
NNCVSSIENM ENISTARAKG RAWIRVALME KRMSEYITTA LRDTRTTRRF
160 170 180 190 200
YDSGAIMMRE EATVLTGMLI GLSAIDFSFC LKGEVLDGKT PVVIDYTPYL
210 220 230 240 250
KFTQSYDYLT DEEERHSAES STSEDNSPEH PYLPLVTDED SWYSKWHKME
260 270 280 290 300
QKFRIVYAQK GYLEELVRLR ESQLKDLEAE NRRLQLQLEE AAAQNQREKR
310 320 330 340 350
ELEGVILELQ EQLTGLIPGD HAPLAQGSKD LTTRLVNQWP SLGTLSGAEG
360 370 380 390 400
ANNPKLYRRH SFMSTEPLSA EASLSSDSQR LGEGKRDEEP WGPIGKDPTP
410 420 430 440
SMLGLCGSLA SIPSCKSLAS FKSNECLVSD SPEGSPALSP S
Length:441
Mass (Da):49,462
Last modified:July 25, 2006 - v1
Checksum:iF9AAD1D27ABC1968
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC118315 mRNA Translation: AAI18316.1
RefSeqiNP_001069790.1, NM_001076322.1
UniGeneiBt.34847

Genome annotation databases

EnsembliENSBTAT00000002119; ENSBTAP00000002119; ENSBTAG00000001615
GeneIDi614322
KEGGibta:614322

Similar proteinsi

Entry informationi

Entry nameiRUN3A_BOVIN
AccessioniPrimary (citable) accession number: Q17QK1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: July 25, 2006
Last modified: March 28, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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