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Protein

Inositol-1-monophosphatase

Gene

5575141

Organism
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Myo-inositol phosphate + H2O = myo-inositol + phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Pathwayi: myo-inositol biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes myo-inositol from D-glucose 6-phosphate.UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Inositol-1-monophosphatase (5575141), Inositol-1-monophosphatase (5565872), Inositol-1-monophosphatase, Inositol-1-monophosphatase (5565741)
This subpathway is part of the pathway myo-inositol biosynthesis, which is itself part of Polyol metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes myo-inositol from D-glucose 6-phosphate, the pathway myo-inositol biosynthesis and in Polyol metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00823; UER00788.

Names & Taxonomyi

Protein namesi
Recommended name:
Inositol-1-monophosphataseUniRule annotation (EC:3.1.3.25UniRule annotation)
Gene namesi
Name:5575141Imported
ORF Names:AAEL000372Imported
OrganismiAedes aegypti (Yellowfever mosquito) (Culex aegypti)Imported
Taxonomic identifieri7159 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeCulicinaeAediniAedesStegomyia
Proteomesi
  • UP000008820 Componenti: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi7159.AAEL000372-PA.

Structurei

3D structure databases

ProteinModelPortaliQ17PJ1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the inositol monophosphatase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2951. Eukaryota.
COG0483. LUCA.
HOGENOMiHOG000282238.
InParanoidiQ17PJ1.
KOiK01092.
OMAiNNYAEFC.
OrthoDBiEOG091G0D21.
PhylomeDBiQ17PJ1.

Family and domain databases

CDDicd01639. IMPase. 1 hit.
InterProiView protein in InterPro
IPR033942. IMPase.
IPR020583. Inositol_monoP_metal-BS.
IPR020552. Inositol_monoPase_Li-sen.
IPR000760. Inositol_monophosphatase-like.
IPR020550. Inositol_monophosphatase_CS.
PANTHERiPTHR20854. PTHR20854. 1 hit.
PfamiView protein in Pfam
PF00459. Inositol_P. 1 hit.
PRINTSiPR00377. IMPHPHTASES.
PR00378. LIIMPHPHTASE.
PROSITEiView protein in PROSITE
PS00629. IMP_1. 1 hit.
PS00630. IMP_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q17PJ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLDLDECYE HVLGLVEQAG QIIASRNYGE KTVVEKSSNI DLLTETDQQV
60 70 80 90 100
ERLLMDGITE KYPDHKFIGE EETSAGKKAE LSDNPTWIID PVDGTMNFVH
110 120 130 140 150
SFPHSCISIA LLVNKQAEIG IIYNPMLNQK FTARRGKGAF MNEKAIRVSG
160 170 180 190 200
ETRLEHALAT TEFGTSRDEE RTAIVLENIG KLIRVVHGMR SLGSAALNMA
210 220 230 240 250
MVALGGADFN YECGIHAWDI AAGDLIVREA GGVCLDPAGG PLDLMSRRVL
260 270
CASSQELADK VVPLLTQYYP QPRD
Length:274
Mass (Da):30,066
Last modified:July 25, 2006 - v1
Checksum:iB549382EFE53A530
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH477191 Genomic DNA. Translation: EAT48626.1.
RefSeqiXP_001655518.1. XM_001655468.1.
UniGeneiAae.10844.

Genome annotation databases

EnsemblMetazoaiAAEL000372-RA; AAEL000372-PA; AAEL000372.
GeneIDi5575141.
KEGGiaag:AaeL_AAEL000372.
VectorBaseiAAEL000372-RA; AAEL000372-PA; AAEL000372.

Similar proteinsi

Entry informationi

Entry nameiQ17PJ1_AEDAE
AccessioniPrimary (citable) accession number: Q17PJ1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: August 30, 2017
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported