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Q17GS9 (ARM_AEDAE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Armadillo segment polarity protein
Gene names
Name:arm
ORF Names:AAEL002887
OrganismAedes aegypti (Yellowfever mosquito) (Culex aegypti) [Reference proteome]
Taxonomic identifier7159 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeCulicinaeAediniAedesStegomyia

Protein attributes

Sequence length832 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

May associate with CadN and participate in the transmission of developmental information. Can associate with alpha-catenin. Accumulates through wg signaling; arm function in wg signal transduction is required early in development for determination of neuroblast fate. Arm and Abl proteins function cooperatively at adherens junctions in both the CNS and epidermis By similarity. UniProtKB P18824

Subcellular location

Cytoplasm By similarity. Cell membrane; Peripheral membrane protein; Cytoplasmic side By similarity. Cell junctionadherens junction By similarity. Note: Inner surface of cell membrane and adherens junction By similarity. UniProtKB P18824

Sequence similarities

Belongs to the beta-catenin family.

Contains 9 ARM repeats.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 832832Armadillo segment polarity protein
PRO_0000312833

Regions

Repeat146 – 18540ARM 1
Repeat188 – 22841ARM 2
Repeat230 – 26940ARM 3
Repeat272 – 31140ARM 4
Repeat356 – 39540ARM 5
Repeat397 – 43438ARM 6
Repeat483 – 52442ARM 7
Repeat594 – 63441ARM 8
Repeat636 – 67540ARM 9

Sequences

Sequence LengthMass (Da)Tools
Q17GS9 [UniParc].

Last modified July 25, 2006. Version 1.
Checksum: 6331B575249EE484

FASTA83290,307
        10         20         30         40         50         60 
MSYQMPQNRT MSHNPYNSSD MPMPSAKEQT LMWQQNSYLG DSGIHSGAVT QVPSLSGKDD 

        70         80         90        100        110        120 
DMEDDPLMFD MDQGFSQNFT QDQVDDMNQQ LSQTRSQRVR AAMFPETLEE GIEIPSTQFD 

       130        140        150        160        170        180 
PQQPTAVQRL SEPSQMLKHA VVNLINYQDD ADLATRAIPE LIKLLNDEDQ VVVSQAAMMV 

       190        200        210        220        230        240 
HQLSKKEASR HAIMNSPQMV AALVRALSQS NDLETTKGAV GTLHNLSHHR QGLLAIFKSG 

       250        260        270        280        290        300 
GIPALVKLLS SPVESVLFYA ITTLHNLLLH QDGSKMAVRL AGGLQKMVAL LQRNNVKFLA 

       310        320        330        340        350        360 
IVTDCLQILA YGNQESKLII LASTGPSELV RIMRSYDYEK LLWTTSRVLK VLSVCSSNKP 

       370        380        390        400        410        420 
AIVEAGGMQA LAMHLGNPSQ RLVQNCLWTL RNLSDAATKV DGLETLLSGL VTVLGSSDVN 

       430        440        450        460        470        480 
VVTCAAGILS NLTCNNQRNK VTVCQVGGVE ALVGTIINAG DREEITEPAV CALRHLTSRH 

       490        500        510        520        530        540 
PESESAQNIV RNGYGLPVIV KLLNPPSRWP LIKAVIGLIR NLALCPSNAA PLREHGAIHL 

       550        560        570        580        590        600 
LVRLLFKAFQ DTQRQRSSVA TNGSQPPGAY ADGVRMEEIV EGTVGALHIL SKEELNRQLI 

       610        620        630        640        650        660 
RQQNVISIFV QLLFYNDIEN IQRVAAGVLC ELAVDKEVAE MIEAEGATAP LTELLNSANE 

       670        680        690        700        710        720 
GVATYAAAVL FKMSEDKSMD YKKRFSSELT TLPVFRDDTM WNNGELGIGP DLQDILSPDQ 

       730        740        750        760        770        780 
AYEGLYGQGP PSVHSSHGGR AFQQGYDTLP IDSMQGLEIG GGGNAGPAGS NPNAGNNPGA 

       790        800        810        820        830 
GGPPSGQPTS PYAMDMDVGE MDASELTFDH LDVMPSPPQD NNQVAAWYDT DL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH477256 Genomic DNA. Translation: EAT45858.1.
RefSeqXP_001662670.1. XM_001662620.1.
UniGeneAae.7915.

3D structure databases

ProteinModelPortalQ17GS9.
SMRQ17GS9. Positions 147-676.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING7159.AAEL002887-PA.

Proteomic databases

PRIDEQ17GS9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaAAEL002887-RA; AAEL002887-PA; AAEL002887.
GeneID5576477.
KEGGaag:AaeL_AAEL002887.
VectorBaseAAEL002887. Aedes aegypti.

Phylogenomic databases

eggNOGNOG297695.
HOGENOMHOG000230958.
KOK02105.
OMAQLSQTRS.
OrthoDBEOG7X9G6B.
PhylomeDBQ17GS9.

Family and domain databases

Gene3D1.25.10.10. 1 hit.
InterProIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
IPR013284. Beta-catenin.
IPR002553. Clathrin/coatomer_adapt-like_N.
[Graphical view]
PfamPF01602. Adaptin_N. 1 hit.
PF00514. Arm. 3 hits.
[Graphical view]
PRINTSPR01869. BCATNINFAMLY.
SMARTSM00185. ARM. 11 hits.
[Graphical view]
SUPFAMSSF48371. SSF48371. 1 hit.
PROSITEPS50176. ARM_REPEAT. 9 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameARM_AEDAE
AccessionPrimary (citable) accession number: Q17GS9
Entry history
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: July 25, 2006
Last modified: February 19, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families