Q17CQ8 (ZGPAT_AEDAE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Zinc finger CCCH-type with G patch domain-containing protein

Gene names

ORF Names:

AAEL004458

Organism

Aedes aegypti (Yellowfever mosquito) (Culex aegypti) [Reference proteome]

Taxonomic identifier

7159 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicimorpha › Culicoidea › Culicidae › Culicinae › Aedini › Aedes › Stegomyia

Protein attributes

Sequence length	512 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transcription repressor By similarity.
Subcellular location	Nucleus By similarity.
Sequence similarities	Contains 1 C3H1-type zinc finger. Contains 1 G-patch domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Domain	Zinc-finger
Ligand	DNA-binding Metal-binding Zinc
Molecular function	Repressor
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 512	512	Zinc finger CCCH-type with G patch domain-containing protein		PRO_0000385198
Regions
	Domain	308 – 354	47	G-patch
	Zinc finger	159 – 186	28	C3H1-type

Sequences

	Sequence		Length	Mass (Da)
	Q17CQ8 [UniParc]. Last modified July 25, 2006. Version 1. Checksum: EC4D317BDB56427E	FASTA	512	57,487
	10 20 30 40 50 60 MSGSQDLNDS IRIYNEQLAQ VEQALEGTSS GPERESLINL KSDLEELVKL TLETVQHENG 70 80 90 100 110 120 DDLNAAASGS NEDDEFALFM REINALDDPG SVDAKPPKPD EVSVDEQEPF KDLVGSKCSA 130 140 150 160 170 180 PHIHKWGSKS YHNALICSLD ASDLDDVAAK VLFINPTHQE MVPCAYFLEG DCKFNDEMCR 190 200 210 220 230 240 FSHGELISIN ELKEYREPRF ELLRKKGCKV LAKNRNRIWS KGTIQTADFE TKTCKIQMDE 250 260 270 280 290 300 GRHEVELQFE NVLPLEGDDV PSSDSESNSD SDEENEDDVV SLQQAQIIER SLLNPAPDQR 310 320 330 340 350 360 LGDWEKHTKG IGSKIMLKMG YVVGAGLGSK GEGIVVPVSA QVLPQGRSLD YCMQLREQAN 370 380 390 400 410 420 GDKNLFSVEK KLQREKRIQE KRDAKNYAAN KSKKDVFNFL NSEIFGSSNG SSSSSGSKKP 430 440 450 460 470 480 AAKDNQMDLP SCSSKNLNIA SLKLSEQMRR LELDIDRLSH SLTRHQPGSK MHSNLQKQIA 490 500 510 EKRREISEIK KTEYSISREQ QLRNDKRKMT VF

References

[1]

"Genome sequence of Aedes aegypti, a major arbovirus vector." Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J., Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P. , Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J., Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W., Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O., Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W. Science 316:1718-1723(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LVPib12.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH477305 Genomic DNA. Translation: EAT44138.1.
RefSeq	XP_001649219.1. XM_001649169.1.
UniGene	Aae.12719.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	AAEL004458-RA; AAEL004458-PA; AAEL004458.
GeneID	5564857.
KEGG	aag:AaeL_AAEL004458.
VectorBase	AAEL004458. Aedes aegypti.
Phylogenomic databases
eggNOG	NOG241375.
HOGENOM	HOG000122451.
OMA	AWGTLEY.
OrthoDB	EOG444J1N.
PhylomeDB	Q17CQ8.
Family and domain databases
InterPro	IPR000467. G_patch_dom. IPR000571. Znf_CCCH. [Graphical view]
Pfam	PF01585. G-patch. 1 hit. [Graphical view]
SMART	SM00443. G_patch. 1 hit. SM00356. ZnF_C3H1. 1 hit. [Graphical view]
PROSITE	PS50174. G_PATCH. 1 hit. PS50103. ZF_C3H1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ZGPAT_AEDAE

Accession

Primary (citable) accession number: Q17CQ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	July 25, 2006
Last modified:	April 3, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)