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Protein

Delta-like protein

Gene

AAEL005082

Organism
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Putative Notch ligand involved in the mediation of Notch signaling.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinUniRule annotation

Keywords - Ligandi

CalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Delta-like proteinUniRule annotation
Gene namesi
ORF Names:AAEL005082Imported
OrganismiAedes aegypti (Yellowfever mosquito) (Culex aegypti)Imported
Taxonomic identifieri7159 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeCulicinaeAediniAedesStegomyia
Proteomesi
  • UP000008820 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1119 – 1142HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi7159.AAEL005082-PA.

Structurei

3D structure databases

ProteinModelPortaliQ17B84.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini201 – 245DSLInterPro annotationAdd BLAST45
Domaini246 – 279EGF-likeInterPro annotationAdd BLAST34
Domaini313 – 351EGF-likeInterPro annotationAdd BLAST39
Domaini457 – 493EGF-likeInterPro annotationAdd BLAST37
Domaini495 – 537EGF-likeInterPro annotationAdd BLAST43
Domaini539 – 574EGF-likeInterPro annotationAdd BLAST36
Domaini576 – 612EGF-likeInterPro annotationAdd BLAST37
Domaini614 – 649EGF-likeInterPro annotationAdd BLAST36
Domaini667 – 707EGF-likeInterPro annotationAdd BLAST41
Domaini709 – 745EGF-likeInterPro annotationAdd BLAST37
Domaini747 – 785EGF-likeInterPro annotationAdd BLAST39
Domaini787 – 823EGF-likeInterPro annotationAdd BLAST37
Domaini825 – 861EGF-likeInterPro annotationAdd BLAST37

Keywords - Domaini

EGF-like domainUniRule annotationSAAS annotation, RepeatUniRule annotationSAAS annotation, SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1217. Eukaryota.
ENOG410XP6K. LUCA.
HOGENOMiHOG000113124.
InParanoidiQ17B84.
KOiK06052.
OMAiMPGAPDK.
OrthoDBiEOG091G0A88.
PhylomeDBiQ17B84.

Family and domain databases

InterProiIPR001774. DSL.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR013111. EGF_extracell.
IPR009030. Growth_fac_rcpt_.
IPR026219. Jagged/Serrate.
IPR001007. VWF_dom.
[Graphical view]
PfamiPF01414. DSL. 1 hit.
PF00008. EGF. 6 hits.
PF07974. EGF_2. 1 hit.
PF07645. EGF_CA. 1 hit.
PF12661. hEGF. 2 hits.
[Graphical view]
PRINTSiPR02059. JAGGEDFAMILY.
SMARTiSM00051. DSL. 1 hit.
SM00181. EGF. 15 hits.
SM00179. EGF_CA. 9 hits.
SM00215. VWC_out. 1 hit.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 7 hits.
PS51051. DSL. 1 hit.
PS00022. EGF_1. 14 hits.
PS01186. EGF_2. 9 hits.
PS50026. EGF_3. 12 hits.
PS01187. EGF_CA. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q17B84-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSGTAKLIK VSSSGFFEMQ ILEIANTNSH LLSGYCCGLP ATKQRLQTTG
60 70 80 90 100
CPACATAFRL CLKEYQGTTS SSSGQQQLKS QKQQGSSSAA EALLLADEPQ
110 120 130 140 150
TAASSAMYGC AFGNASTPTL GGSSFVLSDS EVGRVTLPFT FRWTKSFTLI
160 170 180 190 200
LQALDMYNES YPIADRLIEE TSFSGVILPS HEWNTLDHTG KNARITYRVR
210 220 230 240 250
VQCADNYYNT TCTTFCRPRN DQFGHYTCGE QGNKVCLPGW QGANCEQAIC
260 270 280 290 300
KPGCDQIHGK CDQPGGCECR PGWRGPLCNE CMVYPGCRHG YCNGSAWQCI
310 320 330 340 350
CDTNWGGILC DQDLNYCGTH EPCMHGGTCE NTAPDQYRCT CAEGLSGTRC
360 370 380 390 400
EIVEHPCAPQ PCRNGGTCTL TGSGLGRGSA ADDKLAAAEA TSTTPIIVRG
410 420 430 440 450
MRGMSSMGKP FGRSSGSGGG GGDGSSSSKE PLLQPQPVKD FICSCAPGWT
460 470 480 490 500
GPTCEINIDE CAEGPCQNGG TCIDMVGKFR CECPPQWTGE TCNIDVDECE
510 520 530 540 550
TNVASGLGPC INAESCRNLP GSFQCSCLEG WGGPTCAQNL DDCVGRCKNG
560 570 580 590 600
ATCIDLVNDY HCACAVGYTG RDCSTDINEC ANFPCRNGGE CVDLIGNFKC
610 620 630 640 650
ICPLGYSGTL CEEAKDHCTS SPCIEGRCLN TPGGYYCHCP PGRAGKHCEY
660 670 680 690 700
LRTPCDSPPC LNDGCTMTNE TSGSTALTPC SGRGKCESST LGSSCVCQTG
710 720 730 740 750
FTGPFCQHNV NECFSNPCKN SGICIDGDAD YTCECPPGWT GKNCADRAVQ
760 770 780 790 800
CLPGQCLNGG SCILSPISGI SQCRCTLGWG GPFCNEPVDQ CQGQPCHNGG
810 820 830 840 850
TCESGPGWFR CLCARGFSGP DCRINVNECS PQPCLGGATC KDGIGGFTCL
860 870 880 890 900
CPVGRRGVRC EILLSDPSSV CSNTTTNSPY DPLVTSDSST PTAPIDESNC
910 920 930 940 950
NSCVCVNGKP RCSNMWCGLR NCLNKNLSNS ACESHQVCVP AAQESCLAPP
960 970 980 990 1000
CAPRGDCRTF EPSRRVAPPR IPAPIDCWPN QATLGTHCAR ISILMELNRL
1010 1020 1030 1040 1050
SRGTSVDGMC HLLRLQLGEK LVKSPSIDVT VFVVVMCDLK TGTNDTIEVT
1060 1070 1080 1090 1100
LSTPTDTSNS ASSPLTEAVR LLAEILSRQQ GVQNDSFQTD VAEAAPLTSI
1110 1120 1130 1140 1150
LEVKVETALI NETNAGSNYL IAVGFGIAIV ALCVGAFVAL VWRQKLQSHS
1160 1170 1180 1190 1200
GSGTNLTPHM DLSRSHEEEK SNNLQNEENF RRYANPLKGS ASSLRGAMEL
1210 1220 1230 1240 1250
SLNPAPEINQ IAGPSTVHRS QQLYPSCGND AEFEKDPEKQ KAANRNSHIL
1260 1270 1280 1290 1300
LHKTQNSDIT KNIVSSIESQ HKDFGKRSIN EHTAPGGVAM PPSTPSSASV
1310 1320 1330
VMPVNGAVVV SSVATAPSST APTAMIDSDV LTVHV
Length:1,335
Mass (Da):141,514
Last modified:July 25, 2006 - v1
Checksum:i6D3CD722248BB4FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH477325 Genomic DNA. Translation: EAT43482.1.
RefSeqiXP_001650292.1. XM_001650242.1.

Genome annotation databases

EnsemblMetazoaiAAEL005082-RA; AAEL005082-PA; AAEL005082.
GeneIDi5565937.
KEGGiaag:AaeL_AAEL005082.
VectorBaseiAAEL005082-RA; AAEL005082-PA; AAEL005082.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH477325 Genomic DNA. Translation: EAT43482.1.
RefSeqiXP_001650292.1. XM_001650242.1.

3D structure databases

ProteinModelPortaliQ17B84.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7159.AAEL005082-PA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiAAEL005082-RA; AAEL005082-PA; AAEL005082.
GeneIDi5565937.
KEGGiaag:AaeL_AAEL005082.
VectorBaseiAAEL005082-RA; AAEL005082-PA; AAEL005082.

Phylogenomic databases

eggNOGiKOG1217. Eukaryota.
ENOG410XP6K. LUCA.
HOGENOMiHOG000113124.
InParanoidiQ17B84.
KOiK06052.
OMAiMPGAPDK.
OrthoDBiEOG091G0A88.
PhylomeDBiQ17B84.

Family and domain databases

InterProiIPR001774. DSL.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR013111. EGF_extracell.
IPR009030. Growth_fac_rcpt_.
IPR026219. Jagged/Serrate.
IPR001007. VWF_dom.
[Graphical view]
PfamiPF01414. DSL. 1 hit.
PF00008. EGF. 6 hits.
PF07974. EGF_2. 1 hit.
PF07645. EGF_CA. 1 hit.
PF12661. hEGF. 2 hits.
[Graphical view]
PRINTSiPR02059. JAGGEDFAMILY.
SMARTiSM00051. DSL. 1 hit.
SM00181. EGF. 15 hits.
SM00179. EGF_CA. 9 hits.
SM00215. VWC_out. 1 hit.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 7 hits.
PS51051. DSL. 1 hit.
PS00022. EGF_1. 14 hits.
PS01186. EGF_2. 9 hits.
PS50026. EGF_3. 12 hits.
PS01187. EGF_CA. 6 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ17B84_AEDAE
AccessioniPrimary (citable) accession number: Q17B84
Entry historyi
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: November 30, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.